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Российский кардиологический журнал

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ЭНДОТОКСИНЕМИЯ И АТЕРОСКЛЕРОЗ

Аннотация

Изучается гипотеза вовлечения бактериальных липолоисахаридов наразвитие и прогрессирование атеросклероза. Специальный акцент седлан на частоте эндотоксинемии, времени продолжения действия биоактивного эндотоксина в тканях, связи междлу атеросклерозом и инфекциями, вызванными грам-отрицательными бактериями, плазменными и клеточными мишенями, а также проатерогенным действием эндотоксина. Высказано и детально обсуждено предположение о возможной роли комплексов ЛПС-липопротеин. Представлены литературные данные по эффектам эндотоксина на метаболизм липопротеинов и образование пенистых клеток. 

Об авторах

Я. Ш. Шварц
НИИТ СО РАМН, НИИКИ СО РАМН, Новосибирск
Россия


М. И. Душкин
НИИТ СО РАМН, НИИКИ СО РАМН, Новосибирск
Россия


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Для цитирования:


Шварц Я.Ш., Душкин М.И. ЭНДОТОКСИНЕМИЯ И АТЕРОСКЛЕРОЗ. Российский кардиологический журнал. 2001;(4):83-92.

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Schwarz Y.S., Dushkin M.I. ENDOTOXINEMIA AND ATHEROSCLEROSIS. Russian Journal of Cardiology. 2001;(4):83-92. (In Russ.)

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