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GIANT CELL MYOCARDITIS IN HIV INFECTION: A FATAL TANDEM

https://doi.org/10.15829/1560-4071-2018-2-129-133

Abstract

Giant cell myocarditis (GCM) is a rare autoimmune disease with the leading role of T-cell disorder in its pathogenesis. The associations are known of this disease with various autoimmunities, tumors, drug hypersensitivity. In the literary data there are just single cases of HCM development in HIV infected patients. The article presents clinical case and provides some discussion on the pathogenesis of HCM, making to think of HIV infection as one of possible causes of its development.

About the Authors

S. Yu. Nikulina
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


P. A. Shesternya
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


A. K. Kirichenko
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


A. A. Chernova
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


D. A. Brusentsov
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


V. A. Shulman
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


References

1. UNAIDS report: Global AIDS update 2016. Available from: http://www.unaids.org/sites/default/files/media_asset/global-AIDS-update-2016_en.pdf.

2. Yakushin SS, Filippov EV. HIV infection and cardiovascular complications. The clinician 2011; 2: 6-12. (In Russ.) Якушин С. С., Филиппов Е. В. ВИЧ-инфекция и сердечнососудистые осложнения. Клиницист 2011, 2: 6-12.

3. Lumsden RH, Bloomfield GS. The causes of HIV-associated cardiomyopathy: a tale of two worlds. BioMed Research International 2016. https://www.hindawi.com/journals/ bmri/2016/8196560/.

4. Shostak NA, Klimenko AA, Shemenkova VS, et al. Non-rheumatic myocarditides. The clinician 2015; 3: 46-51. (In Russ.) Шостак Н. А., Клименко А. А., Шеменкова В. С. и др. Неревматические миокардиты. Клиницист 2015, 3: 46-51.

5. Shaboodien G, Maske C, Wainwright H, et al. Prevalence of myocarditis and cardiotropic virus infection in Africans with HIV-associated cardiomyopathy, idiopathic dilated cardiomyopathy and heart transplant recipients: a pilot study: cardiovascular topic. Cardiovascular Journal of Africa 2013; 6: 218-23.

6. Caforio ALP, Pankuweit S, Arbustini E, et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. European Heart Journal 2013; 34: 2636-48.

7. Guidelines for the management of myocarditis. Eurasian Heart Journal 2015; 3: 5-17. (In Russ.) Клинические рекомендации по диагностике и лечению миокардитов. Евразийский кардиологический журнал 2015; 3: 5-17.

8. Noutsias M, Tschöpe C. Giant cell myocarditis: still a conundrum. The need for a worldwide registry. European Journal of Heart Failure 2016; 12: 1459-61. DOI: 10.1002/ejhf.648

9. Pavlikova EP, Petrochenkova MV, Teraz YaM, et al. Giant cell myocarditis with fulminant pericarditis in HIV infection. Terapevticheskiy arkhiv 2007; 11: 45-8. (In Russ.) Павликова Е. П., Петроченкова М. В., Тераз Я. М. и др. Гигантоклеточный миокардит с перикардитом фульминантного течения на фоне ВИЧ-инфекции. Терапевтический архив 2007, 11: 45-8.

10. Ikeda Y, Inomata T, Nishinarita R, et al. Giant cell myocarditis associated with multiple autoimmune disorders following highly active antiretroviral therapy for human immunodeficiency virus type 1 infection. International Journal of Cardiology 2016; 1: 79-81. DOI: 10.1016/j.ijcard.2016.01.061

11. Kandolin R, Lehtonen J, Salmenkivi K, et al. Diagnosis, treatment and outcome of giantcell myocarditis in the era of combined immunosuppression. Circulation: Heart Failure 2013; 6: 15-22.

12. Ekström K, Lehtonen J, Kandolin R, et al. Incidence, risk factors and outcome of lifethreatening ventricular arrhythmias in giant cell myocarditis. Circulation: Arrhythmia and Electrophysiology 2016; 9: e004559.

13. Gilotra NA, Minkove N, Bennett MK, et al. Lack of relationship between serum cardiac troponin I level and giant cell myocarditis diagnosis and outcomes. Journal of Cardiac Failure 2016; 7: 583-5. DOI: 10.1016/j.cardfail.2015.12.022

14. Stiermaier T, Föhrenbach F, Klingel K, et al. Biventricular endomyocardial biopsy in patients with suspected myocarditis: Feasibility, complication rate and additional diagnostic value. International Journal of Cardiology 2017; 230: 364-70. DOI: 10.1016/j.ijcard.2016.12.103

15. Kiselnik D, Wolak A, Abu-Shakra M, et al. Acute myocarditis and myopathy as presenting manifestations of human immunodeficiency virus infection. The Israel Medical Association Journal 2015; 8: 524-5.


Review

For citations:


Nikulina S.Yu., Shesternya P.A., Kirichenko A.K., Chernova A.A., Brusentsov D.A., Shulman V.A. GIANT CELL MYOCARDITIS IN HIV INFECTION: A FATAL TANDEM. Russian Journal of Cardiology. 2018;(2):129-133. (In Russ.) https://doi.org/10.15829/1560-4071-2018-2-129-133

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)