White coat hypertension in non-differentiated connective tissue dysplasia: constitutional characteristics and endothelial-platelet dysfunction
Abstract
In total, 15 patients with nоn-differentiated connective tissue dysplasia (CTD) and white coat hypertension (WCH), 10 WCH-free individuals, and 10 healthy volunteers aged 18-30 years were examined. CTD and WCH patients had greater body weight and body mass index than DCT individuals without WCH. CTD and WCH combination was associated with increased levels of adrenalin and ADP-induced platelet aggregation, endothelin-1, as well as with reduced 6-keto-prostaglandin F1α (6-keto-PGF1α) concentration. In CTD without WCH, collagen-induced platelet aggregation and Willebrand factor activity were decreased.
About the Authors
N. N. Gladkikh
Ставропольская государственная медицинская академия МЗ и СР РФ
Russian Federation
Russian Federation
A. V. Yagoda
Ставропольская государственная медицинская академия МЗ и СР РФ
Russian Federation
Russian Federation
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Review
For citations:
Gladkikh N.N., Yagoda A.V. White coat hypertension in non-differentiated connective tissue dysplasia: constitutional characteristics and endothelial-platelet dysfunction. Russian Journal of Cardiology. 2007;(2):61-65. (In Russ.)
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