Lipid metabolism in patients with vegetative-dyshormonal cardiopathy of various genesis

Abstract

The study was aimed at investigating lipid profile dynamics inpatients with vegetative-dyshormonal cardiopathy (VDC) of various genesis, and assessing the need for lipid-lowering therapy in this coronary heart disease-free group. Lipid levels were measured in 34 participants with VDC, pathological climax and menopause, 30 women with fibromyoma uteri, 32 - with premenstrual syndrome, and 39 - with post-castration syndrome. In all four groups, mean total cholesterol (TCH) level was higher than its Russian norm (5 mmol/l), and mean alpha-CH level was higher than the female norm of 1,2 mmol/l. Calculated on the basis of mean TCH and alpha-CH levels, atherogenicity index was below 3 in all four groups. Mild changes in low-density lipoprotein CH were observed in each group, with the minimal manifestation in premenstrual syndrome participants. Non-pharmaceutical therapy should be administered to all VDC patients; the decision on pharmaceutical treatment should be made individually.