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Cardiovascular disease prevalence in climacteric women with manifested knee osteoarthrosis

Abstract

The aim of the study was to assess cardiovascular disease (CVD) prevalence in climacteric women with knee osteoarthrosis (OA) and joint functional deficiency. The case-control study included 117 women with clinical and X-ray signs of knee OA. The control group included 117 OA-free women. Anthropometry, lipid metabolism parameters, prevalence of arterial hypertension, coronary heart disease (CHD)), chronic heart failure, acute stroke and transient ischemic attack were assessed. Women with OA had greater body mass index, waist circumference, climacteric syndrome severity, and decreased levels of high-density lipoproteins. Knee OA was associated with increased prevalence of AH (odds ratio, OR,2,18; 95 % CI 1,24-3, 84), metabolic syndrome (OR = 3, 44; 95 % CI 1, 95-6, 07), and stable effort angina (OR = 2, 47; 95 % CI 1, 08-5, 69). In all climacteric women with OA, individual cardiovascular risk should be assessed.

About the Authors

N. V. Izmozherova
Уральская государственная медицинская академия
Russian Federation


A. A. Popov
Уральская государственная медицинская академия
Russian Federation


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For citations:


Izmozherova N.V., Popov A.A. Cardiovascular disease prevalence in climacteric women with manifested knee osteoarthrosis. Russian Journal of Cardiology. 2006;(5):60-63. (In Russ.)

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ISSN 1560-4071 (Print)
ISSN 2618-7620 (Online)