СРАВНИТЕЛЬНАЯ ФАРМАКОЭКОНОМИЧЕСКАЯ ОЦЕНКА ЭНОКСАПАРИНА И НЕФРАКЦИОНИРОВАННОГО ГЕПАРИНА ПРИ ОСТРОМ КОРОНАРНОМ СИНДРОМЕ БЕЗ ПОДЪЕМА СЕГМЕНТА ST
Аннотация
Острый коронарный синдром (ОКС) – форма ишемической болезни, объединяющая острый инфаркт миокарда с подъемом сегмента ST (ОКС с подъемом сегмента ST), острый инфаркт миокарда без подъема сегмента ST и нестабильную стенокардию (ОКС без подъема сегмента ST). Эти состояния объединены в единый синдром в связи с высоким риском развития острого инфаркта миокарда и острой коронарной смерти у этой группы больных, что и определяет особую актуальность лечения ОКС. Применение антикоагулянтов, в частности, эноксапарина или нефракционированного гепарина является базисным компонентом медикаментозного лечения ОКС без подъема сегмента ST (ОКСбпST). Целью настоящего исследования являлось выявление антикоагулянта, обладающего клиническими и фармако-экономическими преимуществами при консервативном лечении ОКСбпST.
Об авторах
А. В. Сыров
Клинический госпиталь МСЧ ГУВД
Россия
сотрудник
Россия
сотрудник
С. К. Зырянов
Клинический госпиталь МСЧ ГУВД
Россия
профессор кафедры
Россия
профессор кафедры
Ю. Б. Белоусов
Российский государственный медицинский университет, кафедра
клинической фармакологии, Москва
Россия
зав. кафедрой и курсом, член-корреспондент РАМН, профессор, д.м.н.
Россия
зав. кафедрой и курсом, член-корреспондент РАМН, профессор, д.м.н.
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Рецензия
Для цитирования:
Сыров А.В., Зырянов С.К., Белоусов Ю.Б. СРАВНИТЕЛЬНАЯ ФАРМАКОЭКОНОМИЧЕСКАЯ ОЦЕНКА ЭНОКСАПАРИНА И НЕФРАКЦИОНИРОВАННОГО ГЕПАРИНА ПРИ ОСТРОМ КОРОНАРНОМ СИНДРОМЕ БЕЗ ПОДЪЕМА СЕГМЕНТА ST. Российский кардиологический журнал. 2010;(2):59-66.
For citation:
Syrov A.V., Zyryanov S.K., Belousov Yu.B. PHARMACO-ECONOMIC COMPARISON OF ENOXAPARIN AND UNFRACTIONATED HEPARIN IN ACUTE CORONARY SYNDROME WITHOUT ST SEGMENT ELEVATION. Russian Journal of Cardiology. 2010;(2):59-66. (In Russ.)
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