CARDIOPROTECTION POTENTIAL IN CORONARY HEART DISEASE TREATMENT
Abstract
Aim. To investigate effectiveness and safety of trimetazidine MB in the complex treatment of stable angina. In total, 90 patients were examined – 57 women and 33 men aged 48-70 years (mean age 61,4 ± 6,03 years). All participants received trimetazidine MB (Deprenorm MB) for 3 months (35 mg twice per day). The treatment was associated with reduced angina attack incidence and decreased dose of isosorbide dinitrate, taken during angina attacks. Functional class (FC) of angina was also reduced. Conclusion. Deprenorm MB could be recommended for complex treatment of the patients with coronary heart disease and stable effort angina, who already receive standard anti-anginal therapy.
About the Authors
N. A. Shostak
Кафедра факультетской терапии им. акад. А.И. Нестерова ГОУ ВПО РГМУ Росздрава, Москва
Russian Federation
Russian Federation
O. G. Smolenskaya
кафедра внутренних болезней №1 с курсом эндокринологии и клинической фармакологии ГОУ ВПР УГМА Росздрава, Екатеринбург
Russian Federation
Russian Federation
A. V. Panov
ФГУ ФЦСКиЭ им. В.А. Алмазова Росмедтехнологий, Санкт-Петербург
Russian Federation
Russian Federation
A. A. Klimenko
Кафедра факультетской терапии им. акад. А.И. Нестерова ГОУ ВПО РГМУ Росздрава, Москва
Russian Federation
Russian Federation
D. Yu. Andriyashkina
Кафедра факультетской терапии им. акад. А.И. Нестерова ГОУ ВПО РГМУ Росздрава, Москва
Russian Federation
Russian Federation
N. A. Tverdova
Кафедра факультетской терапии им. акад. А.И. Нестерова ГОУ ВПО РГМУ Росздрава, Москва
Russian Federation
Russian Federation
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Review
For citations:
Shostak N.A., Smolenskaya O.G., Panov A.V., Klimenko A.A., Andriyashkina D.Yu., Tverdova N.A. CARDIOPROTECTION POTENTIAL IN CORONARY HEART DISEASE TREATMENT. Russian Journal of Cardiology. 2009;(6):25-28. (In Russ.)
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