SLEEP APNOEA SYNDROME EFFECTS ON CLINICAL COURSE AND QUALITY OF LIFE IN PATIENTS WITH CORONARY HEART DISEASE
Abstract
Aim. The sleep apnoea syndrome (SAS) is a widely prevalent but under-studied condition which might aggravate the clinical course of various diseases. This study aimed to assess the influence of SAS on the clinical course of coronary heart disease (CHD) and quality of life (QoL) of CHD patients. Material and methods. The study included 186 patients with various CHD forms and 24 controls with angiographically confirmed absence of CHD. The patients were divided into groups of effort angina, post-infarction cardiosclerosis without chronic heart failure (CHF), and with Functional Class (FC) II–III CHF (NYHA classification). All participants underwent cardiorespiratory monitoring and QoL assessment (WHOQOL-BREF and SAQL questionnaires). Based on the SAS severity, two subgroups with low (0–10 per hour) and high (11–30 per hour) index of apnoeahypopnoea (AHI) were defined. Results. SAS affected the clinical course and QoL to the greatest extent in patients with CHF. Among effort angina patients, this effect was weaker, while no negative impact of SAS was registered in patients with post-infarction cardiosclerosis without CHF. Conclusion. The management of CHD patients should incorporate the screening for possible SAS and target SAS, if present, as one of the factors aggravating the clinical course of the main pathology.
About the Author
O. Yu. Shaidyuk
N.I. Pirogov Russian Research Medical University, Moscow
Russian Federation
Russian Federation
References
1. Young T., Peppard E. P., Gottlieb D. J. Epidemiology of Obstructive sleep apnea. Am J Respir Crit Care Med; 2002; 165:1217–39.
2. Menon L., Rudraraju P., Danial V. et al. Prevalence of symptoms of obstructive sleep apnea in patients attending an inner City Primary Care Clinic. Int J Pub Health, 2011; 1.DOI:10.5580/198a.
3. Loke Y.K., Brown J. W. L., Kwok CS et al. Association of obstructive sleep apnea with risk of serious cardiovascular events. Circulation Outcomes, 2012; July 24.DOI:10.1161.
4. Vozoris N. T. Sleep apnea-plus: prevalence, risk factors and association with cardiovascular diseases using US population-level data. Sleep Med, 2012 Jun; 13 (6):636–44.
5. Jacobsen J. H., Shi L., Mokhlesi B. Factors associated with excessive daytime sleepiness in patients with severe obstructive sleep apnea. Sleep Breath, 2012 Jun; DOI:10.1007.
6. Cherniack N.S. Sleep apnea and insomnia: sleep apnea plus or minus. Respiration, 2005; 72:458–9.
7. Jaffe L.M., Kjekshus J., Gottlieb SS. Importance and management of chronic sleep apnea in cardiology. Eur Heart J, 2012; DOI: 10.1093.
8. The National Guidelines on Diagnostics and Treatment of Chronic Heart Failure, Mareev V. Yu, Ageev F. T., Arutyunov G.P. et al. (ed.). Serdechnaya Nedostatochnost, 2010; 11 (1)-57. Russian (Диагностика и лечение хронической сердечной недостаточности: национальные рекомендации. Под ред. Мареева В.Ю., Агеева Ф. Т., Арутюнова Г. П. и др. Сердечная недостаточность, 2010; т. 11 (1)-57).
9. Ram S., Seirawan H., Clark G. T. et al. Prevalence and impact of sleep disorders and sleep habits in the US. Sleep Breath, 2010; 14:63–70.
10. Murphy B., Herrman H., Hawthorne G. et al. Australian WHOQoL instruments: User’s manual and interpretation guide. Australian WHOQoL Field Study Centre, 2000.
Review
For citations:
Shaidyuk O.Yu. SLEEP APNOEA SYNDROME EFFECTS ON CLINICAL COURSE AND QUALITY OF LIFE IN PATIENTS WITH CORONARY HEART DISEASE. Russian Journal of Cardiology. 2012;(5):70-74. (In Russ.)
Views:
521
Email this article 