PROGNOSTIC ROLE OF C-REACTIVE PROTEIN AND CARDIAC EVENT RISK
Abstract
This review focuses on endothelium interaction with inflammatory mediators. C-reactive protein (CRP) plays a role in inflammation activation, endothelin-1 production increase, and lipid peroxidation enhancement, which results in endothelial dysfunction. The other consequences include vasoconstriction, blood pressure increase, thrombosis, and, finally, cardiovascular events.
About the Authors
O. V. Milyutina
Кировская государственная медицинская академия Росздрава, кафедра внутренних болезней, Киров
Russian Federation
Competing Interests: ассистент
Russian Federation
Competing Interests: ассистент
E. N. Chicherina
Кировская государственная медицинская академия Росздрава, кафедра внутренних болезней, Киров
Russian Federation
Russian Federation
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Review
For citations:
Milyutina O.V., Chicherina E.N. PROGNOSTIC ROLE OF C-REACTIVE PROTEIN AND CARDIAC EVENT RISK. Russian Journal of Cardiology. 2011;(1):71-73. (In Russ.)
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