Aortic dissection in a patient with Turner syndrome: a case report

Introduction. Turner syndrome is a genetic disorder caused by complete or partial monosomy of the X chromosome. This disease is characterized by polymorphism of congenital malformations, with predominant involvement of the endocrine and cardiovascular systems. Patients with Turner syndrome demonstrate higher morbidity and mortality rates compared to the general population, which requires comprehensive interdisciplinary approach to their management.

Brief description. The article presents a case of a patient with verified Turner syndrome (45,X karyotype), who was diagnosed with intravital aortic dissection (DeBakey type III), which became possible due to a comprehensive examination. The work describes in detail the characteristic phenotypic manifestations, clinical performance and course, analysis of risk factors, applied diagnostic and treatment methods.

Discussion. The key task of managing patients with hereditary connective tissue disorders is to maintain a high level of clinical alertness among physicians of all specialties. It is critically important not only to recognize the specific risks associated with the genetic syndrome, but also to carefully assess potential trigger factors that can provoke vascular events. Expedited clinical suspicion and verification of life-threatening emergencies, including aortic dissection, require the selection of emergent therapeutic interventions and could reduce mortality.

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