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Clinical features of post-COVID-19 period. Results of the international register “Dynamic analysis of comorbidities in SARS-CoV-2 survivors (AKTIV SARS-CoV-2)”. Data from 6-month follow-up

  G. P. Arutyunov,   E. I. Tarlovskaya,   A. G. Arutyunov,   Yu. N. Belenkov,   A. O. Konradi,   Yu. M. Lopatin,   A. P. Rebrov,   S. N. Tereshchenko,   A. I. Chesnikova,   H. G. Hayrapetyan, A. P. Babin,   I. G. Bakulin,   N. V. Bakulina,   L. A. Balykova,   A. S. Blagonravova,   M. V. Boldina,   A. R. Vaisberg,   A. S. Galyavich,   V. V. Gomonova,   N. Yu. Grigorieva,   I. V. Gubareva,   I. V. Demko, A. V. Evzerikhina,   A. V. Zharkov,   U. K. Kamilova,   Z. F. Kim,   T. Yu. Kuznetsova,   N. V. Lareva,   E. V. Makarova,   S. V. Malchikova,   S. V. Nedogoda,   M. M. Petrova,   I. G. Pochinka,   K. V. Protasov,   D. N. Protsenko,   D. Yu. Ruzanau,   S. A. Sayganov,   A. Sh. Sarybaev,   N. M. Selezneva,   A. B. Sugraliev,   I. V. Fomin,   O. V. Khlynova,   O. Yu. Chizhova,   I. I. Shaposhnik, D. A. Shchukarev,   A. K. Abdrahmanova, S. A. Avetisian,   H. G. Avoyan, K. K. Azarian, G. T. Aimakhanova, D. A. Ayipova, A. Ch. Akunov,   M. K. Alieva,   A. V. Aparkina,   O. R. Aruslanova,   E. Yu. Ashina,   O. Yu. Badina,   O. Yu. Barisheva,   T. I. Batluk, A. S. Batchayeva,   R. A. Bashkinov,   A. M. Bitieva,   I. U. Bikhteyev,   N. A. Borodulina,   M. V. Bragin, A. M. Budu,   G. A. Bykova, K. R. Vagapova,   D. D. Varlamova,   N. N. Vezikova,   E. A. Verbitskaya,   O. E. Vilkova,   E. A. Vinnikova,   V. V. Vustina,   E. A. Gаlova,   V. V. Genkel, E. I. Gorshenina,   E. V. Grigorieva,   E. Yu. Gubareva, G. M. Dabylova, I. A. Demchenko, O. Yu. Dolgikh, M. Y. Duyshobayev,   D. S. Evdokimov,   K. E. Egorova,   A. N. Ermilova, A. E. Zheldybayeva, N. V. Zarechnova,   Yu. D. Zimina,   S. Yu. Ivanova,   E. Yu. Ivanchenko,   M. V. Ilina,   M. V. Kazakovtseva, E. V. Kazymova,   Yu. S. Kalinina, N. A. Kamardina,   A. M. Karachenova,   I. A. Karetnikov,   N. A. Karoli,   M. K. Karsiev,   D. S. Кaskaeva,   K. F. Kasymova, Zh. B. Kerimbekova,   A. Sh. Kerimova, E. S. Kim,   N. V. Kiseleva, D. A. Klimenko,   A. V. Klimova,   O. V. Kovalishena, E. V. Kolmakova, T. P. Kolchinskaya,   M. I. Kolyadich,   O. V. Kondriakova,   M. P. Konoval,   D. Yu. Konstantinov,   E. A. Konstantinova, V. A. Kordukova, E. V. Koroleva,   A. Yu. Kraposhina, T. V. Kriukova,   A. S. Kuznetsova,   T. Yu. Kuzmina, K. V. Kuzmichev,   Ch. K. Kulchoroeva,   T. V. Kuprina, I. M. Kouranova, L. V. Kurenkova,   N. Yu. Kurchugina,   N. A. Kushubakova,   V. I. Levankova,   N. A. Lyubavina,   N. A. Magdeyeva, K. V. Mazalov,   V. I. Majseenko,   A. S. Makarova,   A. M. Maripov,   A. A. Marusina,   E. S. Melnikov,   N. B. Moiseenko,   F. N. Muradova, R. G. Muradyan, Sh. N. Musaelian, A. O. Myshak,   E. S. Nekaeva,   N. M. Nikitina, B. B. Ogurlieva,   A. A. Odegova,   Yu. M. Omarova,   N. A. Omurzakova, Sh. O. Ospanova,   E. V. Pahomova, L. D. Petrov,   S. S. Plastinina, V. A. Pogrebetskaya,   D. V. Polyakov,   D. S. Polyakov, E. V. Ponomarenko,   L. L. Popova,   N. A. Prokofeva, I. A. Pudova, N. A. Rakov, A. N. Rakhimov, N. A. Rozanova, S. Serikbolkyzy,   A. A. Simonov,   V. V. Skachkova,   D. V. Soloveva,   I. A. Soloveva, I. M. Sukhomlinova,   A. G. Sushilova, D. R. Tagayeva,   Yu. V. Titojkina,   E. P. Tikhonova, D. S. Tokmin,   A. A. Tolmacheva,   M. S. Torgunakova,   K. V. Trenogina, N. A. Trostianetckaia,   D. A. Trofimov,   M. A. Trubnikova,   A. A. Tulichev, A. T. Tursunova,   N. D. Ulanova,   O. V. Fatenkov,   O. V. Fedorishina,   T. S. Fil, I. Yu. Fomina, I. S. Fominova, I. A. Frolova,   S. M. Tsvinger,   V. V. Tsoma, M. B. Cholponbaeva,   T. I. Chudinovskikh, O. A. Shevchenko, T. V. Sheshina,   E. A. Shishkina,   K. Yu. Shishkov, S. Yu. Sherbakov, E. A. Yausheva

https://doi.org/10.15829/1560-4071-2021-4708

Abstract

Aim. To study the clinical course specifics of coronavirus disease 2019 (COVID-19) and comorbid conditions in COVID-19 survivors 3, 6, 12 months after recovery in the Eurasian region according to the AKTIV register.


Material and methods.The AKTIV register was created at the initiative of the Eurasian Association of Therapists. The AKTIV register is divided into 2 parts: AKTIV 1 and AKTIV 2. The AKTIV 1 register currently includes 6300 patients, while in AKTIV 2 — 2770. Patients diagnosed with COVID-19 receiving in- and outpatient treatment have been anonymously included on the registry. The following 7 countries participated in the register: Russian Federation, Republic of Armenia, Republic of Belarus, Republic of Kazakhstan, Kyrgyz Republic, Republic of Moldova, Republic of Uzbekistan. This closed multicenter register with two nonoverlapping branches (in- and outpatient branch) provides 6 visits: 3 in-person visits during the acute period and 3 telephone calls after 3, 6, 12 months. Subject recruitment lasted from June 29, 2020 to October 29, 2020. Register will end on October 29, 2022. A total of 9 fragmentary analyzes of the registry data are planned. This fragment of the study presents the results of the post-hospitalization period in COVID-19 survivors after 3 and 6 months.


Results. According to the AKTIV register, patients after COVID-19 are characterized by long-term persistent symptoms and frequent seeking for unscheduled medical care, including rehospitalizations. The most common causes of unplanned medical care are uncontrolled hypertension (HTN) and chronic coronary artery disease (CAD) and/or decompensated type 2 diabetes (T2D). During 3- and 6-month follow-up after hospitalization, 5,6% and 6,4% of patients were diagnosed with other diseases, which were more often presented by HTN, T2D, and CAD. The mortality rate of patients in the post-hospitalization period was 1,9% in the first 3 months and 0,2% for 4-6 months. The highest mortality rate was observed in the first 3 months in the group of patients with class II-IV heart failure, as well as in patients with cardiovascular diseases and cancer. In the pattern of death causes in the post-hospitalization period, following cardiovascular causes prevailed (31,8%): acute coronary syndrome, stroke, acute heart failure.


Conclusion. According to the AKTIV register, the health status of patients after COVID-19 in a serious challenge for healthcare system, which requires planning adequate health system capacity to provide care to patients with COVID-19 in both acute and post-hospitalization period.

About the Authors

G. P. Arutyunov
Association "Eurasian Association of Therapists"; Pirogov Russian National Research Medical University
Russian Federation

MD, PhD, professor, corresponding member of the Russian Academy of Sciences, President; Head of the Department of Internal Medicine, Honored Doctor of the Russian Federation 



E. I. Tarlovskaya
Association "Eurasian Association of Therapists"; Privolzhsky Research Medical University
Russian Federation

MD, PhD, Professor, Chairperson of the Eurasian Association of Therapists branch in Nizhny Novgorod; head of the Department of therapy and cardiology



A. G. Arutyunov
Association "Eurasian Association of Therapists"; Pirogov Russian National Research Medical University
Russian Federation

MD, PhD, Professor, Secretary General of the Eurasian Association of Therapists 



Yu. N. Belenkov
The First Moscow state medical University I. M. Sechenov
Russian Federation

Аcademician of RAS, MD, PhD, head of Department of hospital therapy №1 medical faculty 



A. O. Konradi
"Almazov National Medical Research Centre” of the Ministry of Health of the Russian Federation
Russian Federation

Сorresponding member of the Russian Academy of Sciences. MD, PhD, Professor, Deputy General Director of scientific work 



Yu. M. Lopatin
Volgograd State Medical University
Russian Federation

MD, PhD, Professor, Head of the Departrment of Cardiology and Functional Diagnostics, Faculty of Advanced Training for Doctors



A. P. Rebrov
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

PhD, MD, Professor at the Department of the Internal Medicine



S. N. Tereshchenko
"NMIC cardiology" of the Ministry of health of the Russian Federation
Russian Federation

MD, PhD, Professor, head of the Department of myocardial diseases and heart failure 



A. I. Chesnikova
Rostov State Medical University
Russian Federation

MD, PhD, Professor, Professor in the Department of Internal Medicine No.1



H. G. Hayrapetyan
Erebouni Cardiology Center
Armenia

MD, PhD, professor, Head of Cardiology Center, Head of Cardiology Department



A. P. Babin
Nicolae Testemitanu State University of Medicine and Pharmacy
Moldova, Republic of

MD, PhD, Associate Professor, Head of the Department of Family Medicine



I. G. Bakulin
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

MD, PhD, professor, Dean of the General Medicine Faculty, Head of the department of Propedeutics of Internal Diseases, Gastroenterology and Dietology named after S.M. Ryss, Internal Medicine Adviser to the Ministry of Health (the Northwestern federal district of Russia) 



N. V. Bakulina
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

MD, PhD, Professor, Head of the department of Internal Diseases, Clinical Pharmacology and Nephrology



L. A. Balykova
Ogarev Mordovia State University
Russian Federation

MD, PhD, professor, Director of the Medicine Institute, corresponding member of the Russian Academy of Sciences



A. S. Blagonravova
Privolzhsky Research Medical University
Russian Federation

MD, PhD, Vice rector for research, professor of epidemiology, microbiology and evidence based medicine



M. V. Boldina
Privolzhsky Research Medical University
Russian Federation

PhD, associate Professor of the Department of therapy and cardiology



A. R. Vaisberg
Privolzhsky Research Medical University
Russian Federation

PhD, Associate Professor, Department of Therapy and Cardiology



A. S. Galyavich
The Republican Center for Cardiovascular Diseases of State Autonomous Institution of Health "Interregional Clinical Diagnostic Center"; SBEI HPE "Kazan State Medical University"
Russian Federation

MD, PhD, professor,Chief Cardiologist of the Republic of Tatarstan, Corresponding Member of the Academy of Sciences of the Republic of Tatarstan, Head of the Republican Center for Cardiovascular Diseases of State Autonomous Institution of Health "Interregional Clinical Diagnostic Center"; Head of the Department of Faculty Therapy



V. V. Gomonova
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

Deputy Chief Physician



N. Yu. Grigorieva
National Research Lobachevsky State University of Nizhni Novgorod
Russian Federation

MD, PhD, associate Professor, head of the Department of clinical medicine



I. V. Gubareva
Samara State Medical University
Russian Federation

MD, PhD,  Associated Professor, head of Internal Diseases Department



I. V. Demko
Krasnoyarsk state medical University named after Professor V. F. Voino-Yasenetsky; Regional state budgetary healthcare institution "Regional Clinical Hospital" (RSBHI RCH)
Russian Federation

MD, PhD, professor, Head of the Department of Hospital Therapy and Immunology with Postgraduate Education; Head of the Department of Pulmonary Allergology Center,
pulmonologist, allergist-immunologist  



A. V. Evzerikhina
Krasnogorsk city hospital № 1
Russian Federation

PhD, deputy chief physician



A. V. Zharkov
Kirovsk Interdisrict Hospital
Russian Federation

PhD, chief physician



U. K. Kamilova
The Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation
Uzbekistan

MD, PhD, Professor, Deputy Director of Scientific Work



Z. F. Kim
Medical Center "GAUZ GKB №7"
Russian Federation

PhD, associate professor, deputy chief physician



T. Yu. Kuznetsova
Petrozavodsk State University
Russian Federation

MD, PhD, associated professor, head of the department of Faculty Therapy, Phthisiology, Infectious Diseases and Epidemiology, deputy director for postgraduate education



N. V. Lareva
Chita State Medical Academy of Medicine
Russian Federation

MD, PhD, professor, head of the department of Therapy at the Faculty of Advanced Training and Professional Continuing Education



E. V. Makarova
Privolzhsky Research Medical University; "Nizhny Novgorod Research Institute of Hygiene and Occupational Pathology" of Rospotrebnadzor
Russian Federation

MD, PhD, Associate Professor, Head of the Department of Propaedeutics of internal diseases; Senior Researcher



S. V. Malchikova
Kirov State Medical University
Russian Federation

MD, PhD, associate professor, ptofessor of the Department of Clinical Therapy



S. V. Nedogoda
Volgograd State Medical University
Russian Federation

MD, PhD, professor, vice-rector for clinical work and regional health development, head of the Department of Internal Medicine



M. M. Petrova
Krasnoyarsk State Medical University. prof. V.F. Voino-Yasenetsky
Russian Federation

MD, PhD, professor, head of the Department of Polyclinic Therapy and Family Medicine with a Course of Postgraduate Education 



I. G. Pochinka
Privolzhsky Research Medical University; City Clinical Hospital №13 of Nizhniy Novgorod
Russian Federation

MD, PhD, associate professor at the Department of Enocrinology and Internal Medicine; head of the Department of Cardiology №1



K. V. Protasov
Irkutsk State Medical Academy of Postgraduate Education
Russian Federation

MD, PhD, professor, deputy director of research



D. N. Protsenko
Moscow City Clinical Hospital №40; Pirogov Russian National Research Medical University
Russian Federation

PhD, chief physician of The City Clinical Hospital №40; head of the anesthesiology and resuscitation department of the school of continuing medical education



D. Yu. Ruzanau
Educational Institution «Gomel State Medical University»
Belarus

PhD, associate professor, vice-rector for clinical work, professor at the Department of Phthisiology and Pulmonology



S. A. Sayganov
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

MD, PhD, rector, professor, head of the Department of Hospital Therapy and Cardiology



A. Sh. Sarybaev
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

MD, PhD, professor, Head of the National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov



N. M. Selezneva
Ogarev Mordovia State University
Russian Federation

PhD, associate professor at the Department of Hospital Therapy



A. B. Sugraliev
Asfendiyarov Kazakh National Medical University
Kazakhstan

PhD, associate professor, head of the Department of Internal Diseases with a Course of Propaedeutics



I. V. Fomin
Privolzhsky Research Medical University
Russian Federation

MD, PhD, associate professor, head of the department of hospital therapy



O. V. Khlynova
Perm State Medical University named after E.A. Vagner
Russian Federation

MD, PhD, Professor, corresponding member of the Russian Academy of Sciences, Head of the Department of Hospital Therapy



O. Yu. Chizhova
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

MD, PhD, professor at the department of Propedeutics of Internal Diseases, Gastroenterology and Dietology named after S.M. Ryss



I. I. Shaposhnik
South-Ural State Medical University
Russian Federation

MD, PhD, professor, head of the department of the propaedeutics of internal diseases



D. A. Shchukarev
Kirovsk Interdisrict Hospital
Russian Federation

head of department of infectious deseases



A. K. Abdrahmanova
Kazakh University of Continuing Education; Clinical Infectious Diseases Hospital named after I. Zhekenovа
Kazakhstan

PhD, head of the Department of Infectious Diseases, chief physician



S. A. Avetisian
Yerevan State Medical University
Armenia

clinical resident at cardiology department



H. G. Avoyan
Erebouni Cardiology Center
Armenia

cardiologist



K. K. Azarian
Erebouni Cardiology Center
Armenia

cardiologist



G. T. Aimakhanova
Asfendiyarov Kazakh National Medical University
Kazakhstan

PhD, Associate Professor at the Department of Internal Diseases with a course of propaedeutics



D. A. Ayipova
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

head of the department of nephrology



A. Ch. Akunov
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

PhD, head of the Department of urgent cardiology and reanmation-2 



M. K. Alieva
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

therapist



A. V. Aparkina
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

PhD, assistant at the Department of  Hospital Therapy, Medical Faculty



O. R. Aruslanova
Perm Regional Clinical Cardiological Dispensary
Russian Federation

PhD, cardiovascular surgeon



E. Yu. Ashina
Privolzhsky Research Medical University
Russian Federation

assistant at the Department of Propedeutics of Internal Diseases



O. Yu. Badina
The Volga District Medical Centre, Federal Medical and Biological Agency of Russia
Russian Federation

Head of the Infectious Diseases Department



O. Yu. Barisheva
Petrozavodsk State University
Russian Federation

MD, PhD, associated professor, professor of department of hospital therapy



T. I. Batluk
Association “Eurasian Association of Therapists”; Pirogov Russian National Research Medical University
Russian Federation

PhD, Medical adviser; Assistant Lecturer, Department of Internal Medicine Propaedeutics, Pediatric Faculty



A. S. Batchayeva
Pirogov Russian National Research Medical University
Russian Federation

clinical laboratory diagnostician



R. A. Bashkinov
Association “Eurasian Association of Therapists”; North-Western State Medical University named after I.I. Mechnikov
Russian Federation

Medical adviser; postgraduate student of the department of therapy, rheumatology, examination of temporary disability and quality of medical care named after E. E. Eichwald 2019-2022



A. M. Bitieva
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

cardiologist



I. U. Bikhteyev
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

student



N. A. Borodulina
Perm Regional Clinical Cardiological Dispensary
Russian Federation

cardiologist



M. V. Bragin
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

student



A. M. Budu
Clinical City Hospital №1, Kishinev City
Moldova, Republic of

head at the Department of Therapy



G. A. Bykova
Perm State Medical University named after E.A. Vagner
Russian Federation

PhD, associate professor at the Department of Hospital Care, pulmonologist



K. R. Vagapova
FSBI “Polyclinic №1” of the Administrative Directorate of the President of the Russian Federation
Russian Federation

endocrinologist



D. D. Varlamova
Petrozavodsk State University
Russian Federation

2-year student



N. N. Vezikova
Petrozavodsk State University
Russian Federation

Professor, MD, PhD, head of department of hospital therapy



E. A. Verbitskaya
Krasnoyarsk Regional Hospital
Russian Federation

therapist



O. E. Vilkova
National Research Lobachevsky State University of Nizhni Novgorod
Russian Federation

PhD, Senior Lecturer at the Department of Clinical Medicine 



E. A. Vinnikova
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

attending physician



V. V. Vustina
Perm Regional Clinical Hospital
Russian Federation

PhD, cardiologist



E. A. Gаlova
Privolzhsky Research Medical University
Russian Federation

PhD, deputy director for science of the University clinic



V. V. Genkel
South-Ural State Medical University
Russian Federation

PhD, associated professor at the Department of Propedeutics of Internal Medicine 



E. I. Gorshenina
Ogarev Mordovia State University
Russian Federation

PhD, associate professor at the Department of Hospital Care



E. V. Grigorieva
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

PhD, associate professor at the Department of  Hospital Therapy, Medical Faculty



E. Yu. Gubareva
Samara State Medical University
Russian Federation

PhD, assistant of the Department of Faculty Therapy, physician at Functional Diagnostics Department



G. M. Dabylova
Asfendiyarov Kazakh National Medical University
Kazakhstan

assistant of the Department of Internal Diseases with the Course of Propaedeutics  



I. A. Demchenko
Samara State Medical University
Russian Federation

laboratory assistant at the Department of Faculty Therapy, intern doctor



O. Yu. Dolgikh
State Budgetary Institution of Healthcare of the Samara Region "Chapaevskaya Central City Hospital"
Russian Federation

PhD, chief physician



M. Y. Duyshobayev
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

physician at the department of urgent cardiology and reanmation-2



D. S. Evdokimov
North-Western State Medical University named after I. I. Mechnikov
Russian Federation

postgraduate student at the Department of Faculty Therapy 2020-2023 Place of employment: Senior Laboratory Assistant, Department of Faculty Therapy



K. E. Egorova
Republic hospital n.a. V.A. Baranov
Russian Federation

Gastroenterologist of nephrology department



A. N. Ermilova
Association “Eurasian Association of Therapists”; Psychiatric clinical hostpital named after P. Gannushkin
Russian Federation

senior medical advisor, psychiatrist



A. E. Zheldybayeva
Asfendiyarov Kazakh National Medical University
Kazakhstan

assistant of the Department of Internal Diseases with the course of propaedeutics  



N. V. Zarechnova
The Volga District Medical Centre, Federal Medical and Biological Agency of Russia
Russian Federation

deputy chief physician at Clinical Hospital №2



Yu. D. Zimina
City Clinical Hospital No.25
Russian Federation

therapist



S. Yu. Ivanova
State Budgetary Medical Institution Republic of Karelia Hospital for Veterans
Russian Federation

deputy chief physician



E. Yu. Ivanchenko
Privolzhsky Research Medical University
Russian Federation

PhD, associate professor at the department of therapy and cardiology



M. V. Ilina
Kirovsk Interdistrict Hospital
Russian Federation

therapist



M. V. Kazakovtseva
Kirov State Medical University
Russian Federation

PhD, associate professor of the Department of Clinical Therapy



E. V. Kazymova
Private Healthcare Institution "Clinical Hospital RZHD Meditsyna at Samara railway station"
Russian Federation

deputy chief physician



Yu. S. Kalinina
Krasnoyarsk State Medical University. prof. V.F. Voino-Yasenetsky
Russian Federation

assistant at the Department of Нospital Therapy and Immunology with Postgraduate Education Course



N. A. Kamardina
The Volga District Medical Centre, Federal Medical and Biological Agency of Russia
Russian Federation

cardiologist



A. M. Karachenova
Chita State Medical Academy of Medicine
Russian Federation

therapist, pulmonologist



I. A. Karetnikov
Irkutsk regional clinical hospital of Conferred Order of Merit
Russian Federation

deputy chief phisician



N. A. Karoli
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

MD, PhD, professor at the Department of  Hospital Therapy, Medical Faculty



M. K. Karsiev
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

attending physician



D. S. Кaskaeva
Krasnoyarsk State Medical University. prof. V.F. Voino-Yasenetsky
Russian Federation

PhD, associate professor of the Department of Outpatient Therapy and Family Medicine with a Course of Postgraduate Education



K. F. Kasymova
Krasnoyarsk State Medical University named after prof. V.F. Voino-Yasenetsky
Russian Federation

resident of Department of Нospital Therapy and Immunology with Postgraduate Education Course



Zh. B. Kerimbekova
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

junior researcher at the department of mountain medicine and pulmonary hypertension



A. Sh. Kerimova
Moscow City Clinical Hospital №40
Russian Federation

assistant of a chief physician



E. S. Kim
GAUZ GKB №7
Russian Federation

administrator



N. V. Kiseleva
Nizhniy Novgorod City Hospital №40
Russian Federation

therapist



D. A. Klimenko
Samara State Medical University
Russian Federation

laboratory assistant at the Department of Faculty Therapy, intern doctor



A. V. Klimova
Moscow City State Outpatient Hospital №134; Pirogov Russian National Research Medical University
Russian Federation

general practitioner; postgraduate student at the Department of the Internal Medicine



O. V. Kovalishena
Privolzhsky Research Medical University
Russian Federation

MD, PhD, head of the Department of Epidemiology, Microbiology and Evidence-Based Medicine, director of the Research Institute of Preventive Medicine of the University Clinic



E. V. Kolmakova
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

PhD, associate professor at the Department of Internal Diseases, Clinical Pharmacology and Nephrology



T. P. Kolchinskaya
Municipal Autonomous Healthcare Institution of the Order of the Red Banner of Labour "City Clinical Hospital №1" of Chelyabinsk city
Russian Federation

deputy chief physician on outpatient therapy



M. I. Kolyadich
South-Ural State Medical University; Municipal Autonomous Healthcare Institution of the Order of the Red Banner of Labour "City Clinical Hospital №1", Chelyabinsk city
Russian Federation

PhD, associate professor of the Department of Propedeutics of Internal Medicine; deputy chief physician



O. V. Kondriakova
Samara State Medical University
Russian Federation

6-year student



M. P. Konoval
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

therapist



D. Yu. Konstantinov
Samara State Medical University
Russian Federation

MD, PhD, associate professor, head of the Department of Infectious Diseases 



E. A. Konstantinova
Samara State Medical University
Russian Federation

PhD, associate professor at the Department of Infectious Diseases



V. A. Kordukova
Privolzhsky Research Medical University
Russian Federation

resident in pulmonology



E. V. Koroleva
"City clinical hospital №5" of Nizhniy Novgorod
Russian Federation

physician of the department of cardiology №2



A. Yu. Kraposhina
Krasnoyarsk state medical University named after Professor V. F. Voino-Yasenetsky; Regional state budgetary healthcare institution "Regional Clinical Hospital" (RSBHI RCH)
Russian Federation

PhD, associate professor at the Department of Hospital Therapy and Immunology with Postgraduate Education; pulmonologist



T. V. Kriukova
Association "Eurasian Association of Therapists"
Russian Federation

project manager



A. S. Kuznetsova
South-Ural State Medical University
Russian Federation

PhD, associate professor of the Department of Clinical Therapy



T. Yu. Kuzmina
Krasnoyarsk State Medical University. prof. V.F. Voino-Yasenetsky
Russian Federation

PhD, associate professor at the Depatment of Infecction Diseases and Epidemiology



K. V. Kuzmichev
Nizhniy Novgorod City Hospital №13
Russian Federation

resident



Ch. K. Kulchoroeva
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

junior researcher



T. V. Kuprina
Petrozavodsk State University
Russian Federation

postgraduated student



I. M. Kouranova
Gorodetskaya Central City Hospital of Nizhniy Novgorod Region
Russian Federation

deputy chief phhysician



L. V. Kurenkova
Republic hospital n.a. S.V. Katkov
Russian Federation

attending physician



N. Yu. Kurchugina
Samara State Medical University
Russian Federation

4-year student



N. A. Kushubakova
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

junior researcher



V. I. Levankova
Petrozavodsk City polyclinic No. 1
Russian Federation

deputy chief physician for therapy



N. A. Lyubavina
Privolzhsky Research Medical University
Russian Federation

PhD, associated professor



N. A. Magdeyeva
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

PhD, associate professor at the Department of  Hospital Therapy, Medical Faculty



K. V. Mazalov
The Volga District Medical Centre, Federal Medical and Biological Agency of Russia
Russian Federation

head of the Department of Cardiology



V. I. Majseenko
Educational Institution «Gomel State Medical University»
Belarus

assistant lecturer at the Department of Phthisiopulmonology with the course of the Faculty of Professional Development and Retraining



A. S. Makarova
Irkutsk State Medical Academy of Postgraduate Education
Russian Federation

postgraduate student of the department of cardiology and functional diagnostics 



A. M. Maripov
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

head of Department of Pulmonary Hypertension and High altitude medicine of NCCIM, leading researcher



A. A. Marusina
Kirovsk Interdistrict Hospital
Russian Federation

therapist



E. S. Melnikov
Association "Eurasian Association of Therapists"; North-Western State Medical University named after I. I. Mechnikov
Russian Federation

medical advisor; postgraduate student of the department of therapy, rheumatology, examination of temporary disability and quality of medical care named after E. E. Eichwald 2020-2023



N. B. Moiseenko
National Research Lobachevsky State University of Nizhni Novgorod
Russian Federation

student



F. N. Muradova
Privolzhsky Research Medical University
Russian Federation

postgraduate student of the Department of Therapy and Cardiology



R. G. Muradyan
Global Medical System clinics and hospitals
Russian Federation

general practitioner



Sh. N. Musaelian
Yerevan State Medical University
Armenia

clinical resident at cardiology department



A. O. Myshak
Group of companies "Medinvestgroup"
Russian Federation

data analyst



E. S. Nekaeva
Privolzhsky Research Medical University
Russian Federation

Head of the Department of the Reception and Consultation, therapist at the Privolzhsky Research Medical University



N. M. Nikitina
Saratov State Medical University named after V.I. Razumovsky
Russian Federation

MD, PhD, professor at the Department of  Hospital Therapy, Medical Faculty



B. B. Ogurlieva
Pirogov Russian National Research Medical University; Moscow City Clinical Hospital #4
Russian Federation

research assistant; сardiologist



A. A. Odegova
Kirov State Medical University
Russian Federation

PhD, asistant of the Department of Clinical Therapy



Yu. M. Omarova
Privolzhsky Research Medical University
Russian Federation

postgraduate student of the Department of Therapy and Cardiology



N. A. Omurzakova
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

MD, PhD, deputy director



Sh. O. Ospanova
Asfendiyarov Kazakh National Medical University
Kazakhstan

assistant at the Department of Internal Diseases with the Course of Propaedeutics  



E. V. Pahomova
GBUZ RK "Republican tuberculosis dispensary"
Russian Federation

phthisiatrician of the Department of Pulmonary Tuberculosis for Adults



L. D. Petrov
Health Center of Briceni
Moldova, Republic of

director



S. S. Plastinina
Privolzhsky Research Medical University
Russian Federation

PhD, assistant professor at the Internal Medicine Department



V. A. Pogrebetskaya
SBHI of Nizhniy Novgorod Region "City Clinical Hospital #38"
Russian Federation

deputy chief physician



D. V. Polyakov
Pirogov Russian National Research Medical University
Russian Federation

PhD, associate professor of the department of  internal medicine



D. S. Polyakov
Privolzhsky Research Medical University
Russian Federation

PhD, assistant professor at the Department of Therapy and Cardiology



E. V. Ponomarenko
Medical center «Zimamed»
Russian Federation

cardiologist



L. L. Popova
Samara State Medical University
Russian Federation

MD, PhD, professor at the Department of Infectious Diseases



N. A. Prokofeva
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

PhD, head of the department of therapy №2



I. A. Pudova
Privolzhsky Research Medical University; Nizhniy Novgorod city Outpatient Hospital #4
Russian Federation

assistant at the Department of Faculty and Polyclinic Therapy; chief physician



N. A. Rakov
Privolzhsky Research Medical University
Russian Federation

attending physician



A. N. Rakhimov
The Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation
Uzbekistan

junior researcher 



N. A. Rozanova
Krasnogorsk city hospital № 1
Russian Federation

nurse



S. Serikbolkyzy
Asfendiyarov Kazakh National Medical University
Kazakhstan

assistant of the Department of Internal Diseases with the Course of Propaedeutics  



A. A. Simonov
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

therapist



V. V. Skachkova
Perm Regional Clinical Hospital
Russian Federation

attending physician



D. V. Soloveva
National Research Lobachevsky State University of Nizhni Novgorod
Russian Federation

resident



I. A. Soloveva
Krasnoyarsk State Medical University. prof. V.F. Voino-Yasenetsky; Regional state budgetary healthcare institution "Regional Clinical Hospital" (RSBHI RCH)
Russian Federation

MD, PhD, associate professor; pulmonologist, allergologist-immunologist



I. M. Sukhomlinova
Saint-Petersburg hospital for veterans
Russian Federation

therapist



A. G. Sushilova
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

resident



D. R. Tagayeva
The Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation
Uzbekistan

junior researcher 



Yu. V. Titojkina
Ogarev Mordovia State University
Russian Federation

resident



E. P. Tikhonova
Krasnoyarsk State Medical University. prof. V.F. Voino-Yasenetsky
Russian Federation

MD, PhD, professor, head of the Department of Infectious Diseases and Epidemiology with a Course of Postgraduate Education



D. S. Tokmin
Labs of the Future
Russian Federation

head of analytics



A. A. Tolmacheva
Novosibirsk State Medical University; SBHCI of Novosibirsk region "Clinical Polyclinic #27"
Russian Federation

postgraduate student, assistant of the department of Faculty Therapy n.a. Zalesskiy G.D., therapist



M. S. Torgunakova
Krasnoyarsk State Medical University. prof. V.F. Voino-Yasenetsky
Russian Federation

resident of Department of Нospital Therapy and Immunology with Postgraduate Education Course



K. V. Trenogina
Perm Regional Clinical Hospital
Russian Federation

PhD, cardiologist



N. A. Trostianetckaia
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

PhD, cardiologist



D. A. Trofimov
Kazan State Medical University; Medical Center "GAUZ GKB №7"
Russian Federation

student, nurse (Department of Cardiology №4)



M. A. Trubnikova
Association "Eurasian Association of Therapists"; LLC “Fresenius Medical Care Kuban”
Russian Federation

medical advisor; nephrologist



A. A. Tulichev
Privolzhsky Research Medical University; SBHI of Nizhniy Novgorod region City Clinical Hospital #3
Russian Federation

PhD, assistant of Department of Internal Medicine Propedeutics;  head of the Emergency Room



A. T. Tursunova
Asfendiyarov Kazakh National Medical University
Kazakhstan

assistant of the Department of Internal Diseases with the Course of Propaedeutics  



N. D. Ulanova
Nizhniy Novgorod City Hospital #13
Russian Federation

resident



O. V. Fatenkov
Samara State Medical University
Russian Federation

MD, PhD, assistant professor, director,  head of the Department of Faculty Therapy, cheef freelance therapist of the Ministry of Healthcare of Samara Region



O. V. Fedorishina
Irkutsk State Medical Academy of Postgraduate Education
Russian Federation

PhD, associate professor at the department of cardiology and functional diagnostics



T. S. Fil
North-Western State Medical University named after I.I. Mechnikov
Russian Federation

PhD, head of the department of gastroenterology, therapist



I. Yu. Fomina
Privolzhsky Research Medical University; SBHI of Nizhniy Novgorod region City Outpatient Hospital #1
Russian Federation

PhD, associate professor at the Department of Faculty and Outpatient Therapy; chief physician 



I. S. Fominova
Clinical Hospital #4 of Republic Mordovia
Russian Federation

neurologist



I. A. Frolova
The Volga District Medical Centre, Federal Medical and Biological Agency of Russia
Russian Federation

cardiologist



S. M. Tsvinger
Chita State Medical Academy of Medicine
Russian Federation

PhD, rheumatologist, associate professor at the department of ambulatory care with courses of  medical rehabilitation



V. V. Tsoma
Volgograd State Medical University
Russian Federation

PhD, associate professor, Department of Internal Medicine, Institute of Continuing Medical Education, head of Additional Professional Education Department, chief freelance pulmonologist of the Health Committee of the Volgograd Region



M. B. Cholponbaeva
National Center of Cardiology and Internal Medicine named after prof. M. Mirrakhimov
Kyrgyzstan

junior researcher



T. I. Chudinovskikh
Kirov State Medical University
Russian Federation

PhD, assistant of the Department​ of Hospital Therapy



O. A. Shevchenko
SBHI of Samara Region "Samara City Polyclinic #3"
Russian Federation

general practitioner



T. V. Sheshina
National Research Lobachevsky State University of Nizhni Novgorod
Russian Federation

assistant at the department of clinical medicine



E. A. Shishkina
Perm State Medical University named after E.A. Vagner
Russian Federation

MD, PhD, associate professor at the Hopspital Therapy and Cardiology Department



K. Yu. Shishkov
Samara State Medical University
Russian Federation

6-year student



S. Yu. Sherbakov
Kazan State Medical Academy
Russian Federation

resident in anaesthesiology and resuscitation



E. A. Yausheva
Ruzaevka city RZHD-Medicine hospital
Russian Federation

endocrinologist



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Arutyunov G.P., Tarlovskaya E.I., Arutyunov A.G., Belenkov Yu.N., Konradi A.O., Lopatin Yu.M., Rebrov A.P., Tereshchenko S.N., Chesnikova A.I., Hayrapetyan H.G., Babin A.P., Bakulin I.G., Bakulina N.V., Balykova L.A., Blagonravova A.S., Boldina M.V., Vaisberg A.R., Galyavich A.S., Gomonova V.V., Grigorieva N.Yu., Gubareva I.V., Demko I.V., Evzerikhina A.V., Zharkov A.V., Kamilova U.K., Kim Z.F., Kuznetsova T.Yu., Lareva N.V., Makarova E.V., Malchikova S.V., Nedogoda S.V., Petrova M.M., Pochinka I.G., Protasov K.V., Protsenko D.N., Ruzanau D.Yu., Sayganov S.A., Sarybaev A.Sh., Selezneva N.M., Sugraliev A.B., Fomin I.V., Khlynova O.V., Chizhova O.Yu., Shaposhnik I.I., Shchukarev D.A., Abdrahmanova A.K., Avetisian S.A., Avoyan H.G., Azarian K.K., Aimakhanova G.T., Ayipova D.A., Akunov A.Ch., Alieva M.K., Aparkina A.V., Aruslanova O.R., Ashina E.Yu., Badina O.Yu., Barisheva O.Yu., Batluk T.I., Batchayeva A.S., Bashkinov R.A., Bitieva A.M., Bikhteyev I.U., Borodulina N.A., Bragin M.V., Budu A.M., Bykova G.A., Vagapova K.R., Varlamova D.D., Vezikova N.N., Verbitskaya E.A., Vilkova O.E., Vinnikova E.A., Vustina V.V., Gаlova E.A., Genkel V.V., Gorshenina E.I., Grigorieva E.V., Gubareva E.Yu., Dabylova G.M., Demchenko I.A., Dolgikh O.Yu., Duyshobayev M.Y., Evdokimov D.S., Egorova K.E., Ermilova A.N., Zheldybayeva A.E., Zarechnova N.V., Zimina Yu.D., Ivanova S.Yu., Ivanchenko E.Yu., Ilina M.V., Kazakovtseva M.V., Kazymova E.V., Kalinina Yu.S., Kamardina N.A., Karachenova A.M., Karetnikov I.A., Karoli N.A., Karsiev M.K., Кaskaeva D.S., Kasymova K.F., Kerimbekova Zh.B., Kerimova A.Sh., Kim E.S., Kiseleva N.V., Klimenko D.A., Klimova A.V., Kovalishena O.V., Kolmakova E.V., Kolchinskaya T.P., Kolyadich M.I., Kondriakova O.V., Konoval M.P., Konstantinov D.Yu., Konstantinova E.A., Kordukova V.A., Koroleva E.V., Kraposhina A.Yu., Kriukova T.V., Kuznetsova A.S., Kuzmina T.Yu., Kuzmichev K.V., Kulchoroeva Ch.K., Kuprina T.V., Kouranova I.M., Kurenkova L.V., Kurchugina N.Yu., Kushubakova N.A., Levankova V.I., Lyubavina N.A., Magdeyeva N.A., Mazalov K.V., Majseenko V.I., Makarova A.S., Maripov A.M., Marusina A.A., Melnikov E.S., Moiseenko N.B., Muradova F.N., Muradyan R.G., Musaelian Sh.N., Myshak A.O., Nekaeva E.S., Nikitina N.M., Ogurlieva B.B., Odegova A.A., Omarova Yu.M., Omurzakova N.A., Ospanova Sh.O., Pahomova E.V., Petrov L.D., Plastinina S.S., Pogrebetskaya V.A., Polyakov D.V., Polyakov D.S., Ponomarenko E.V., Popova L.L., Prokofeva N.A., Pudova I.A., Rakov N.A., Rakhimov A.N., Rozanova N.A., Serikbolkyzy S., Simonov A.A., Skachkova V.V., Soloveva D.V., Soloveva I.A., Sukhomlinova I.M., Sushilova A.G., Tagayeva D.R., Titojkina Yu.V., Tikhonova E.P., Tokmin D.S., Tolmacheva A.A., Torgunakova M.S., Trenogina K.V., Trostianetckaia N.A., Trofimov D.A., Trubnikova M.A., Tulichev A.A., Tursunova A.T., Ulanova N.D., Fatenkov O.V., Fedorishina O.V., Fil T.S., Fomina I.Yu., Fominova I.S., Frolova I.A., Tsvinger S.M., Tsoma V.V., Cholponbaeva M.B., Chudinovskikh T.I., Shevchenko O.A., Sheshina T.V., Shishkina E.A., Shishkov K.Yu., Sherbakov S.Yu., Yausheva E.A. Clinical features of post-COVID-19 period. Results of the international register “Dynamic analysis of comorbidities in SARS-CoV-2 survivors (AKTIV SARS-CoV-2)”. Data from 6-month follow-up. Russian Journal of Cardiology. 2021;26(10):4708. https://doi.org/10.15829/1560-4071-2021-4708

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