Heart rate variability and central hemodynamic parameters in patients with post3infarctial cardiosclerosis and chronic heart failure
Abstract
Autonomic regulation in patients with post-infarctial cardiosclerosis (PICS) and chronic heart failure (CHF) was investigated. Eighty-eight patients with PICS were examined. Various cardiovascular tests, heart rate variability, and central hemodynamic parameters were assessed with integral rheography method at rest and during orthotest in Groups 1 and 2. Group 1 included patients with PICS and CHF, Group 2 - with PICS only. Compared with Group 2, Group 1 had more pronounced abnormalities of sympathic and parasympathic autonomic nervous system (ANS), lower heart rate variability, autonomic shift to sympathic hypertonus, and less balanced reaction to orthotest. Such a dynamics of heart rate variability and hemodynamic parameters at rest as well as during orthotest in patients with PICS and CHF is an evidence of more advanced disturbancies of autonomic regulation and hemodynamics in this clinical group.
About the Authors
A. D. Ibatov
Московская медицинская академия им. И.М.Сеченова
Russian Federation
Russian Federation
M. G. Poltavskaya
Московская медицинская академия им. И.М.Сеченова
Russian Federation
Russian Federation
A. L. Syrkin
Московская медицинская академия им. И.М.Сеченова
Russian Federation
Russian Federation
References
1. Вариабельность сердечного ритма. Стандарты измерения, физиологической интерпретации и клинического использования. Рабочая группа Европейского Кардиологического Общества и Северо-Американского общества стимуляции и электрофизиологии (Рекомендации).//Вестник аритмологии. 1999. № 11. С. 53-78.
2. Вегетативные расстройства: Клиника, лечение, диагностика/Под ред. А.М. Вейна. М.: Медицинское информационное агентство, 2000. 725 с.
3. Мареев В.Ю. Оценка функционального состояния и прогноза больных с сердечной недостаточностью. Роль HOLTER-мониторирования и ЭКГ//Труды Первого международного научного форума «Кардиология-99» 28-31 января 1999. ЗАО «МОРАГ ЭКСПО», 1999. 110-113 с.
4. Eckberg D.L., Drabinsky M., Braunwald E. Detective cardiac parasympathetic control in patients with heart disease//N. Engl. J. Med. 1971. V. 285. P. 877-882 p.
5. Esler M., Kaye D., Lambert G., et al. Adrenergic nervous system in heart failure. Am. J. Cardiol. 1997; 80: 71-141.
6. Ferguson D.W., Abboud F.M., Mark A.L. Selective impairment of baroreflex-mediated vasoconstrictor responses in patients with ventricular dysfunction. Circulation. 1984; 69: 451.
7. Francis G.S., Goldsmith S.R., Levine T.V., et al. The neurohumoral axis in congestive heart failure. Ann. Intern. Med. 1984; 101: 370.
8. Heart disease: a textbook of cardiovascular medicine/ed. by E. Braunwald, D.P. Zipes, P. Libby. W.B. Saunders company; 2001. 6th ed. Vol. 1. 1086 p.
9. Levine Т.В. Francis G.S., Goldsmith S.R., et al. Dissociation of response of the renin-angiotensin system and sympathetic nervous system to a vasodilatator stimulus in congestive heart failure. Int. J. Cardiol. 1986; 12: 165.
10. Vogel J.H.K., Chidsey C.A. Cardiac adrenergic activity in experimental heart failure assessed with beta-receptor blockade. Am. J. Cardiol. 1969; 24: 198-205.
Review
For citations:
Ibatov A.D., Poltavskaya M.G., Syrkin A.L. Heart rate variability and central hemodynamic parameters in patients with post3infarctial cardiosclerosis and chronic heart failure. Russian Journal of Cardiology. 2004;(3):26-30. (In Russ.)
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