Age-related changes in vascular structure and function among obese women
Abstract
The study aimed at investigating age-related changes in vascular structure and function among obese women. In total, 83 obese females and 45 women with normal weight were divided into four age subgroups. Duplex ultrasound of common carotid arteries (CCA) and brachial arteries was performed; endothelium-dependent vasodilatation (EDVD) was studied in reactive hyperemia test. Significant increase in CCA intima-media thickness (IMT), CCA IM diameter, and EDVD reduction was observed in obese women from all age groups, compared to non-obese females. There was a strong positive correlation between IMT and age-related IM diameter increase, and a weaker, but still significant correlation between IMT and body mass index or waist/hip ratio. EDVD negatively correlated with age and waist/hip ratio.
About the Authors
D. P. Kotova
Российская медицинская академия последипломного образования Росздрава
Russian Federation
Russian Federation
A. G. Avtandilov
Российская медицинская академия последипломного образования Росздрава
Russian Federation
Russian Federation
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Review
For citations:
Kotova D.P., Avtandilov A.G. Age-related changes in vascular structure and function among obese women. Russian Journal of Cardiology. 2008;(4):20-24. (In Russ.)
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