HIGH PREVALENCE OF METABOLIC SYNDROME IN SIBERIAN MEN WITH CORONARY ATHEROSCLEROSIS
Abstract
In 42-70-year-old Siberian men with coronary atherosclerosis, verified by coronary angiography, the prevalence of metabolic syndrome (MS) was as high as 89%, which suggests an important role of MS in atherosclerosis development in the Siberian region. In pre-existing coronary atherosclerosis, biomarkers of inflammation and destruction (highly sensitive C-reactive protein, inflammatory cytokines, and destructive metalloproteinases) correlated with MS components, reflecting the pathophysiological role of inflammation in MS development.
About the Authors
M. I. Voevoda
Научно-исследовательский институт терапии СО РАМН
Russian Federation
Russian Federation
Yu. I. Ragino
Научно-исследовательский институт терапии СО РАМН
Russian Federation
Russian Federation
A. M. Chernyavsky
Новосибирский НИИ патологии кровообращения Росздрава, Новосибирск
Russian Federation
Russian Federation
S. Yu. Tsymbal
Новосибирский НИИ патологии кровообращения Росздрава, Новосибирск
Russian Federation
Russian Federation
E. V. Semaeva
Новосибирский НИИ патологии кровообращения Росздрава, Новосибирск
Russian Federation
Russian Federation
Ya. V. Polonskaya
Научно-исследовательский институт терапии СО РАМН
Russian Federation
Russian Federation
M. V. Ivanova
Научно-исследовательский институт терапии СО РАМН
Russian Federation
Russian Federation
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Review
For citations:
Voevoda M.I., Ragino Yu.I., Chernyavsky A.M., Tsymbal S.Yu., Semaeva E.V., Polonskaya Ya.V., Ivanova M.V. HIGH PREVALENCE OF METABOLIC SYNDROME IN SIBERIAN MEN WITH CORONARY ATHEROSCLEROSIS. Russian Journal of Cardiology. 2010;(1):65-69. (In Russ.)
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