INTRACORONARY AUTOLOGOUS BONE MARROW STEM CELL THERAPY IN DIASTOLIC HEART FAILURE
Abstract
A female patient T., 67 years, had a 30-year anamnesis of heart failure, HF (NYHA Functional Class III) with normal left ventricular ejection fraction and Stage II arterial hypertension. After thyroidectomy in 1987, the patient received L-thyroxin. The patient also received long-term standard antihypertensive therapy and HF treatment. Due to ineffective therapy and increased dyspnoea, radionuclide ventriculography was performed, suggesting restrictive cardiomyopathy. Intracoronary injection of autologous bone marrow stem cells was performed. Four months later, an improvement in clinical status (NYHA FC I) was associated with improved diastolic function at ventriculography. Immunological analysis confirmed a virus infection.
About the Authors
V. I. Shumakov
ФГУ ФЦ Трансплантологии и Искусственных Органов РОСЗДРАВА им В.И. Шумакова, Москва
Russian Federation
Russian Federation
E. N. Ostroumov
ФГУ ФЦ Трансплантологии и Искусственных Органов РОСЗДРАВА им В.И. Шумакова, Москва
Russian Federation
Russian Federation
T. V. Gubenko
ФГУ ФЦ Трансплантологии и Искусственных Органов РОСЗДРАВА им В.И. Шумакова, Москва
Russian Federation
Russian Federation
A. Temnov
ФГУ ФЦ Трансплантологии и Искусственных Органов РОСЗДРАВА им В.И. Шумакова, Москва
Russian Federation
Russian Federation
S. V. Gureev
ФГУ ФЦ Трансплантологии и Искусственных Органов РОСЗДРАВА им В.И. Шумакова, Москва
Russian Federation
Russian Federation
N. A. Onishchenko
ФГУ ФЦ Трансплантологии и Искусственных Органов РОСЗДРАВА им В.И. Шумакова, Москва
Russian Federation
Russian Federation
V. S. Suskova
ФГУ ФЦ Трансплантологии и Искусственных Органов РОСЗДРАВА им В.И. Шумакова, Москва
Russian Federation
Russian Federation
N. N. Abramova
ФГУ ФЦ Трансплантологии и Искусственных Органов РОСЗДРАВА им В.И. Шумакова, Москва
Russian Federation
Russian Federation
E. N. Kazakov
ФГУ ФЦ Трансплантологии и Искусственных Органов РОСЗДРАВА им В.И. Шумакова, Москва
Russian Federation
Russian Federation
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Review
For citations:
Shumakov V.I., Ostroumov E.N., Gubenko T.V., Temnov A., Gureev S.V., Onishchenko N.A., Suskova V.S., Abramova N.N., Kazakov E.N. INTRACORONARY AUTOLOGOUS BONE MARROW STEM CELL THERAPY IN DIASTOLIC HEART FAILURE. Russian Journal of Cardiology. 2009;(3):46-52. (In Russ.)
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