CLINICAL AND HEMODYNAMIC INTERRELATIONS OF ARRHYTHMIA COURSE IN CHILDREN OF 0 TO 7 YEARS OLD

Aim. To study clinical and hemodynamic parallels in preschool children with arrhythmias in different age groups.

Material and methods. Totally 195 children studied with idiopathic arrhythmias at the age of 0 to 7 y. o. — 82 with WPW syndrome, 55 with atrial tachiarrhythmias, 7 with AVNRT, 13 — with ventricular tachis (VT), 38 with ventricular and supraventricular onsets (isolated, group and their combination). Age groups: 1 — children 1 y. o. (n=72; 37%); 2 — 1-3 y. o. (n=37; 19%); 3 — 3-7 y. o. (n=87; 44%). All patients underwent standart laboratory assessment, electrocardiography in 12 standard leads, Holter monitoring, echocardiography.

Results. In analysis of tachicardias course variants there was prevalence of of paroxysmal tachicardia in children of 3 to 7 y. o. (p=0,001) and permanent tachicardia in children less than 1 y. o. (p<0,001). Frequency of episodes in paroxysmal tachicardias in 1 y. o. children was higher than in those from 1 to 3 y. o. (p=0,028) and 3-7 y. o. children (p<0,001). In assessment of echocardiography of arrhythmic children depended on age there was significant prevalence of ACMP in older children comparing to the younger (p=0,002). Signs of heart failure were more common in children of 1 y. o. comparing to those of 1-3 and 3-7 y. o. (F=44,117; p=<0,001).

Conclusion. So the arrhythmogenic heart remodeling mostly common for the children of 3 to 7 y. o. In less 1 year infants with arrhythmias clinical signs of HF are followed by diastolic disorders that develop before ACMP development, that is traditionally regarded as systolic dysfunction. Into the factors that influence these hemodynamic relations we include high mean heartrate, tendency of tachicardias to recurrent and permanent course, high frequency of attacks in paroxysmal tachicardias in infants before 1 year old.

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