<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2025-6405</article-id><article-id custom-type="edn" pub-id-type="custom">NIAIKY</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-6405</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЩЕСТВЕННОЕ ЗДОРОВЬЕ И ОРГАНИЗАЦИЯ ЗДРАВООХРАНЕНИЯ</subject></subj-group></article-categories><title-group><article-title>Организация медицинской помощи при остром коронарном синдроме в рамках федерального проекта «Борьба с сердечно-сосудистыми заболеваниями»: результаты и перспективы</article-title><trans-title-group xml:lang="en"><trans-title>Management of health care for acute coronary syndrome within the federal project "Control of Cardiovascular Diseases": results and prospects</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1358-110X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камкин</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kamkin</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Камкин Евгений Геннадьевич — к.м.н., зам. Министра здравоохранения Российской Федерации</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">info@minzdrav.gov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5222-1620</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каракулина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Karakulina</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каракулина Екатерина Валерьевна — к.м.н., директор департамента организации медицинской помощи и санаторно-­курортного дела</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">info@minzdrav.gov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-4819-4405</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гульшина</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gulshina</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гульшина Валерия Александровна — к.б.н., зам. директора департамента организации медицинской помощи и санаторно-­курортного дела</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">info@minzdrav.gov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-0869-2456</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Москалёв</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Moskalev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москалев Андрей Александрович — начальник отдела реализации региональных программ организации медицинской помощи и санаторно-­курортного дела</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">info@minzdrav.gov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-9300-7210</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анисимова</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Anisimova</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анисимова Наталья Сергеевна — к.м.н., зам. начальника отдела реализации региональных программ организации медицинской помощи и санаторно-­курортного дела</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">info@minzdrav.gov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-8509-0488</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазыгула</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazygula</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мазыгула Елена Петровна — к.м.н., руководитель Координационного центра по реализации федерального проекта "Борьба с сердечно-­сосудистыми заболеваниями"</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">mazygula@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иващенко</surname><given-names>Р. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivaschenko</surname><given-names>R. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иващенко Регина Маратовна — зам. руководителя Координационного центра по реализации федерального проекта "Борьба с сердечно-­сосудистыми заболеваниями"</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">reginab_md@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-0064-0192</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чекулаев</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chekulaev</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чекулаев Александр Сергеевич — зав. отделом методической поддержки и координации мероприятий федерального проекта "Борьба с сердечно-сосудистыми заболеваниями"</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">a.chekulaev@internet.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6533-5950</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Звартау</surname><given-names>Н. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvartau</surname><given-names>N. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Звартау Надежда Эдвиновна — к.м.н., зам. генерального директора по работе с регионами, доцент кафедры факультетской терапии с клиникой Института медицинского образования</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">zvartau_ne@almazovcentre.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5656-3978</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлев</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovlev</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлев Алексей Николаевич — к.м.н., начальник службы по развитию регионального здравоохранения Управления по реализации федеральных проектов, зав. научно-­исследовательской лабораторией острого коронарного синдрома, доцент кафедры анестезиологии и реаниматологии лечебного факультета Института медицинского образования</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">yakovlev_an@almazovcentre.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7652-2962</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Виллевальде</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Villevalde</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виллевальде Светлана Вадимовна — д.м.н., профессор, начальник службы анализа и перспективного планирования Управления по реализации федеральных проектов, зав. кафедрой кардиологии факультета послевузовского и дополнительного образования Института медицинского образования</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">villevalde_sv@almazovcentre.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5130-5192</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedeva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Медведева Елена Александровна — к.м.н., зав. отделом стратегического развития кардиологической службы в регионах Управления по реализации федеральных проектов</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">medvedeva_e_a@almazovcentre.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7278-6581</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Недбаева</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Nedbaeva</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Недбаева Дарья Николаевна — специалист отдела мониторинга и анализа показателей регионального здравоохранения Службы по развитию регионального здравоохранения Управления по реализации федеральных проектов</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">nedbaeva_dn@almazovcentre.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9836-7841</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федоренко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorenko</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Федоренко Алексей Александрович — зам. начальника службы по развитию регионального здравоохранения Управления по реализации федеральных проектов</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">fedorenko_aa@almazovcentre.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2428-2375</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Даутов</surname><given-names>Д. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Dautov</surname><given-names>D. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Даутов Дмитрий Рафагатьевич — врач-кардиолог отдела информационного обеспечения и телемедицины Управления по реализации федеральных проектов</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">ddautov97@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2929-0980</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шляхто</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shlyakhto</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шляхто Евгений Владимирович — д.м.н., профессор, академик РАН, генеральный директор, главный внештатный специалист кардиолог Минздрава России Северо-­Западного, Северо-Кавказского, Приволжского и Южного федеральных округов, Херсонской и Запорожской областей</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">fmrc@almazovcentre.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Министерство здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ Центральный научно-исследовательский институт организации и информатизации здравоохранения Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute for Healthcare Organization and Informatization</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ Национальный медицинский исследовательский центр им. В. А. Алмазова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>10</day><month>10</month><year>2025</year></pub-date><volume>30</volume><issue>9</issue><fpage>6405</fpage><lpage>6405</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Камкин Е.Г., Каракулина Е.В., Гульшина В.А., Москалёв А.А., Анисимова Н.С., Мазыгула Е.П., Иващенко Р.М., Чекулаев А.С., Звартау Н.Э., Яковлев А.Н., Виллевальде С.В., Медведева Е.А., Недбаева Д.Н., Федоренко А.А., Даутов Д.Р., Шляхто Е.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Камкин Е.Г., Каракулина Е.В., Гульшина В.А., Москалёв А.А., Анисимова Н.С., Мазыгула Е.П., Иващенко Р.М., Чекулаев А.С., Звартау Н.Э., Яковлев А.Н., Виллевальде С.В., Медведева Е.А., Недбаева Д.Н., Федоренко А.А., Даутов Д.Р., Шляхто Е.В.</copyright-holder><copyright-holder xml:lang="en">Kamkin E.G., Karakulina E.V., Gulshina V.A., Moskalev A.A., Anisimova N.S., Mazygula E.P., Ivaschenko R.M., Chekulaev A.S., Zvartau N.E., Yakovlev A.N., Villevalde S.V., Medvedeva E.A., Nedbaeva D.N., Fedorenko A.A., Dautov D.R., Shlyakhto E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/6405">https://russjcardiol.elpub.ru/jour/article/view/6405</self-uri><abstract><p>Инфаркт миокарда (ИМ) продолжает сохранять статус одного из ключевых жизнеугрожающих сердечно-сосудистых заболеваний с высоким бременем заболеваемости и смертности, включая население трудоспособного возраста. В рамках федерального проекта "Борьба с сердечно-сосудистыми заболеваниями" в Российской Федерации в 2019-2024гг была проведена масштабная модернизация системы оказания медицинской помощи при остром коронарном синдроме и ИМ: расширена сеть региональных сосудистых центров, оптимизирована маршрутизация пациентов, что позволило увеличить охват чрескожным коронарным вмешательством при ИМ с подъемом сегмента ST с 56% до 77%, а при ИМбпST — с 21% до 48%, и достичь снижения смертности от ИМ на 100 тыс. населения на 19,6%, а больничной летальности от ИМ — на 32%. Однако сохраняются межрегиональные различия, в связи с чем необходима дальнейшая работа над повышением доступности и своевременности реперфузионной терапии. В рамках федерального проекта "Борьба с сердечнососудистыми заболеваниями" Национального проекта "Продолжительная и активная жизнь" будет происходить мониторинг целевого показателя охвата реперфузионной терапией больных ИМ, госпитализированных в первые сутки от начала заболевания, уровень которого должен достичь 95% к 2030г. Реализация дополнительных мероприятий позволит сократить дифференциацию показателей между регионами, снизить смертность от болезней системы кровообращения и достичь национальных целей по увеличению продолжительности жизни.</p></abstract><trans-abstract xml:lang="en"><p>Myocardial infarction (MI) continues to retain the status of one of the key lifethreatening cardiovascular diseases with a high morbidity and mortality, including the working-age population. As part of the federal project "Control of Cardiovascular Diseases" in the Russian Federation in 2019-2024, a large-scale modernization of healthcare system for acute coronary syndrome and MI was carried out. The network of regional vascular centers was expanded and patient routing was optimized, which made it possible to increase the coverage of percutaneous coronary intervention for ST-segment elevation MI from 56% to 77%, and for NSTEMI — from 21% to 48%, and to achieve a decrease in mortality from MI per 100 thousand people by 19,6%, and inhospital mortality from MI — by 32%. However, interregional differences remain, and therefore further work is needed to improve the availability and timing of reperfusion therapy. Within the federal project "Control of Cardiovascular Diseases" of the National Project "Long and Active Life", the target indicator of reperfusion therapy coverage of patients with MI hospitalized within the first 24 hours from the disease onset will be monitored. Its level should reach 95% by 2030. Implementation of additional measures will reduce the differentiation of indicators between regions, reduce cardiovascular mortality and achieve national goals to increase life expectancy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый коронарный синдром</kwd><kwd>инфаркт миокарда</kwd><kwd>реперфузионная терапия</kwd><kwd>тромболитическая терапия</kwd><kwd>чрескожное коронарное вмешательство</kwd><kwd>реваскуляризация</kwd><kwd>маршрутизация</kwd><kwd>больничная летальность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute coronary syndrome</kwd><kwd>myocardial infarction</kwd><kwd>reperfusion therapy</kwd><kwd>thrombolytic therapy</kwd><kwd>percutaneous coronary intervention</kwd><kwd>revascularization</kwd><kwd>routing</kwd><kwd>hospital mortality</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аверков О.В., Арутюнян Г.К., Дупляков Д.В. и др. Острый инфаркт миокарда с подъемом сегмента ST электрокардиограммы. Клинические рекомендации 2024. Российский кардиологический журнал. 2025;30(3): 6306. doi:10.15829/1560-4071-2025-6306. EDN: IVJCUK.</mixed-citation><mixed-citation xml:lang="en">Averkov OV, Harutyunyan GK, Duplyakov DV, et al. 2024 Clinical practice guidelines for Acute myocardial infarction with ST segment elevation electrocardiogram. Russian Journal of Cardiology. 2025;30(3):6306. (In Russ.) doi:10.15829/1560-4071-2025-6306. EDN: IVJCUK.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Аверков О.В., Арутюнян Г.К., Дупляков Д.В. и др. Острый коронарный синдром без подъема сегмента ST электрокардиограммы. Клинические рекомендации 2024. Российский кардиологический журнал. 2025;30(5): 6319. doi:10.15829/1560-4071-2025-6319. EDN: CXJUIB.</mixed-citation><mixed-citation xml:lang="en">Averkov OV, Harutyunyan GK, Duplyakov DV, et al. 2024 Clinical practice guidelines for Acute coronary syndrome without ST segment elevation electrocardiogram. Russian Journal of Cardiology. 2025;30(5):6319. (In Russ.) doi:10.15829/1560-4071-2025-6319. EDN: CXJUIB.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Williams C, Fordyce CB, Cairns JA, et al. Temporal Trends in Reperfusion Delivery and Clinical Outcomes Following Implementation of a Regional STEMI Protocol: A 12-Year Perspective. CJC Open. 2022;5(3):181-90. doi:10.1016/j.cjco.2022.11.015.</mixed-citation><mixed-citation xml:lang="en">Williams C, Fordyce CB, Cairns JA, et al. Temporal Trends in Reperfusion Delivery and Clinical Outcomes Following Implementation of a Regional STEMI Protocol: A 12-Year Perspective. CJC Open. 2022;5(3):181-90. doi:10.1016/j.cjco.2022.11.015.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Jortveit J, Pripp AH, Halvorsen S. Outcomes after delayed primary percutaneous coronary intervention vs. pharmaco-¬invasive strategy in ST-segment elevation myocardial infarction in Norway. Eur Heart J Cardiovasc Pharmacother. 2022;8(5):442-51. doi:10.1093/ehjcvp/pvab041.</mixed-citation><mixed-citation xml:lang="en">Jortveit J, Pripp AH, Halvorsen S. Outcomes after delayed primary percutaneous coronary intervention vs. pharmaco-¬invasive strategy in ST-segment elevation myocardial infarction in Norway. Eur Heart J Cardiovasc Pharmacother. 2022;8(5):442-51. doi:10.1093/ehjcvp/pvab041.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Eastwood K, Howell S, Nehme Z, et al. Impact of a mass media campaign on presentations and ambulance use for acute coronary syndrome. Open Heart. 2021;8:e001792. doi:10.1136/openhrt2021-001792.</mixed-citation><mixed-citation xml:lang="en">Eastwood K, Howell S, Nehme Z, et al. Impact of a mass media campaign on presentations and ambulance use for acute coronary syndrome. Open Heart. 2021;8:e001792. doi:10.1136/openhrt2021-001792.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Thygesen K, Alpert JS, Jaffe AS, et al.; ЕОК Scientific Document Group. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40:237-69. doi:10.1161/CIR.0000000000000617.</mixed-citation><mixed-citation xml:lang="en">Thygesen K, Alpert JS, Jaffe AS, et al.; ЕОК Scientific Document Group. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40:237-69. doi:10.1161/CIR.0000000000000617.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Diercks DB, Peacock WF, Hiestand BC, et al. Frequency and consequences of recording an electrocardiogram &gt;10 minutes after arrival in an emergency room in non-¬STsegment elevation acute coronary syndromes (from the CRUSADE Initiative). Am J Cardiol. 2006;97:437-42. doi:10.1016/j.amjcard.2005.09.073.</mixed-citation><mixed-citation xml:lang="en">Diercks DB, Peacock WF, Hiestand BC, et al. Frequency and consequences of recording an electrocardiogram &gt;10 minutes after arrival in an emergency room in non-¬STsegment elevation acute coronary syndromes (from the CRUSADE Initiative). Am J Cardiol. 2006;97:437-42. doi:10.1016/j.amjcard.2005.09.073.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Schmitt C, Lehmann G, Schmieder S, et al. Diagnosis of acute myocardial infarction in angiographically documented occluded infarct vessel: limitations of ST-segment elevation in standard and extended ECG leads. Chest. 2001;120:1540-6. doi:10.1378/chest.120.5.1540.</mixed-citation><mixed-citation xml:lang="en">Schmitt C, Lehmann G, Schmieder S, et al. Diagnosis of acute myocardial infarction in angiographically documented occluded infarct vessel: limitations of ST-segment elevation in standard and extended ECG leads. Chest. 2001;120:1540-6. doi:10.1378/chest.120.5.1540.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Fesmire FM, Percy RF, Bardoner JB, et al. Usefulness of automated serial 12 lead ECG monitoring during the initial emergency department evaluation of patients with chest pain. Ann Emerg Med. 1998;31:3-11. doi:10.1016/S0196-0644(98)70274-4.</mixed-citation><mixed-citation xml:lang="en">Fesmire FM, Percy RF, Bardoner JB, et al. Usefulness of automated serial 12 lead ECG monitoring during the initial emergency department evaluation of patients with chest pain. Ann Emerg Med. 1998;31:3-11. doi:10.1016/S0196-0644(98)70274-4.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Rouan GW, Lee TH, Cook EF, et al. Clinical characteristics and outcome of acute myocardial infarction in patients with initially normal or nonspecific electrocardiograms (a report from the Multicenter Chest Pain Study). Am J Cardiol. 1989;64:1087-92. doi:10.1016/00029149(89)90857-6.</mixed-citation><mixed-citation xml:lang="en">Rouan GW, Lee TH, Cook EF, et al. Clinical characteristics and outcome of acute myocardial infarction in patients with initially normal or nonspecific electrocardiograms (a report from the Multicenter Chest Pain Study). Am J Cardiol. 1989;64:1087-92. doi:10.1016/00029149(89)90857-6.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">McCarthy BD, Wong JB, Selker HP. Detecting acute cardiac ischemia in the emergency department. J Gen Intern Med. 1990;5:365-73. doi:10.1007/BF02600409.</mixed-citation><mixed-citation xml:lang="en">McCarthy BD, Wong JB, Selker HP. Detecting acute cardiac ischemia in the emergency department. J Gen Intern Med. 1990;5:365-73. doi:10.1007/BF02600409.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Savonitto S, Ardissino D, Granger CB, et al. Prognostic value of the admission electrocardiogram in acute coronary syndromes. JAMA. 1999;281:707-13. doi:10.1001/jama.281.8.707.</mixed-citation><mixed-citation xml:lang="en">Savonitto S, Ardissino D, Granger CB, et al. Prognostic value of the admission electrocardiogram in acute coronary syndromes. JAMA. 1999;281:707-13. doi:10.1001/jama.281.8.707.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Дроздов Д.В., Макаров Л.М., Иртюга О.Б. и др. Регистрация электрокардиограммы покоя в 12 общепринятых отведениях взрослым и детям 2023. Методические рекомендации. Российский кардиологический журнал. 2023;28(10):5631. doi:10.15829/1560-4071-2023-5631.</mixed-citation><mixed-citation xml:lang="en">Drozdov DV, Makarov LM, Barkan VS, et al. Resting 12 lead electrocardiography for adults and children. 2023 Guidelines. Russian Journal of Cardiology. 2023;28(10):5631. (In Russ.) doi:10.15829/1560-4071-2023-5631.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Bainey KR, Armstrong PW, Zheng Y, et al. Pharmacoinvasive Strategy Versus Primary Percutaneous Coronary Intervention in ST-Elevation Myocardial Infarction in Clinical Practice: Insights From the Vital Heart Response Registry. Circ Cardiovasc Interv. 2019;12(10):e008059. doi:10.1161/CIRCINTERVENTIONS.119.008059.</mixed-citation><mixed-citation xml:lang="en">Bainey KR, Armstrong PW, Zheng Y, et al. Pharmacoinvasive Strategy Versus Primary Percutaneous Coronary Intervention in ST-Elevation Myocardial Infarction in Clinical Practice: Insights From the Vital Heart Response Registry. Circ Cardiovasc Interv. 2019;12(10):e008059. doi:10.1161/CIRCINTERVENTIONS.119.008059.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Boersma E, Maas AC, Deckers JW, Simoons ML. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet. 1996;348:771-5. doi:10.1016/s0140-6736(96)02514-7.</mixed-citation><mixed-citation xml:lang="en">Boersma E, Maas AC, Deckers JW, Simoons ML. Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour. Lancet. 1996;348:771-5. doi:10.1016/s0140-6736(96)02514-7.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Boersma E. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients. Eur Heart J. 2006;27:779-88. doi:10.1093/eurheartj/ehi810.</mixed-citation><mixed-citation xml:lang="en">Boersma E. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients. Eur Heart J. 2006;27:779-88. doi:10.1093/eurheartj/ehi810.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Byrne RA, Rossello X, Coughlan JJ, et al.; ESC Scientific Document Group. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart J. 2023;44(38):3720-826. doi:10.1093/eurheartj/ehad191.</mixed-citation><mixed-citation xml:lang="en">Byrne RA, Rossello X, Coughlan JJ, et al.; ESC Scientific Document Group. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart J. 2023;44(38):3720-826. doi:10.1093/eurheartj/ehad191.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">O’Gara PT, Kushner FG, Ascheim DD, et al.; American College of Cardiology Foundation/ American Heart Association Task Force on Practice Guidelines. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;127(4):e362-425. doi:10.1161/CIR.0b013e3182742cf6.</mixed-citation><mixed-citation xml:lang="en">O’Gara PT, Kushner FG, Ascheim DD, et al.; American College of Cardiology Foundation/ American Heart Association Task Force on Practice Guidelines. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;127(4):e362-425. doi:10.1161/CIR.0b013e3182742cf6.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Steg PG, James SK, Atar D, et al. Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC); ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2012;33(20):2569-619. doi:10.1093/eurheartj/ehs215.</mixed-citation><mixed-citation xml:lang="en">Steg PG, James SK, Atar D, et al. Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC); ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2012;33(20):2569-619. doi:10.1093/eurheartj/ehs215.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Morrison LJ, Verbeek PR, McDonald AC, et al. Mortality and prehospital thrombolysis for acute myocardial infarction: a meta-analysis. J Am Med Assoc. 2000;283:2686-92. doi:10.1001/jama.283.20.2686.</mixed-citation><mixed-citation xml:lang="en">Morrison LJ, Verbeek PR, McDonald AC, et al. Mortality and prehospital thrombolysis for acute myocardial infarction: a meta-analysis. J Am Med Assoc. 2000;283:2686-92. doi:10.1001/jama.283.20.2686.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">McCaul M, Lourens A, Kredo T. Pre-hospital versus in-hospital thrombolysis for ST-elevation myocardial infarction Cochrane Database Syst Rev. 2014:(9):CD010191. doi:10.1002/14651858.CD010191.pub2.</mixed-citation><mixed-citation xml:lang="en">McCaul M, Lourens A, Kredo T. Pre-hospital versus in-hospital thrombolysis for ST-elevation myocardial infarction Cochrane Database Syst Rev. 2014:(9):CD010191. doi:10.1002/14651858.CD010191.pub2.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Bonnefoy E, Steg PG, Boutitie F, et al. Comparison of primary angioplasty and pre-hospital fibrinolysis in acute myocardial infarction (CAPTIM) trial: a 5 year follow-up. Eur Heart J. 2009;30(13):1598-606. doi:10.1093/eurheartj/ehp156.</mixed-citation><mixed-citation xml:lang="en">Bonnefoy E, Steg PG, Boutitie F, et al. Comparison of primary angioplasty and pre-hospital fibrinolysis in acute myocardial infarction (CAPTIM) trial: a 5 year follow-up. Eur Heart J. 2009;30(13):1598-606. doi:10.1093/eurheartj/ehp156.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Armstrong PW, Gershlick AH, Goldstein P, et al.; STREAM Investigative Team. Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction. N Engl J Med. 2013;368(15):1379-87. doi:10.1056/NEJMoa1301092.</mixed-citation><mixed-citation xml:lang="en">Armstrong PW, Gershlick AH, Goldstein P, et al.; STREAM Investigative Team. Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction. N Engl J Med. 2013;368(15):1379-87. doi:10.1056/NEJMoa1301092.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Ellis SG, da Silva ER, Heyndrickx G, et al.; RЕSCUE Investigators. Randomized comparison of rescue angioplasty with conservative management of patients with early failure of thrombolysis for acute anterior myocardial infarction. Circulation. 1994;90(5):2280-4. doi:10.1161/01.cir.90.5.2280.</mixed-citation><mixed-citation xml:lang="en">Ellis SG, da Silva ER, Heyndrickx G, et al.; RЕSCUE Investigators. Randomized comparison of rescue angioplasty with conservative management of patients with early failure of thrombolysis for acute anterior myocardial infarction. Circulation. 1994;90(5):2280-4. doi:10.1161/01.cir.90.5.2280.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Sutton AGC, Campbell PG, Graham R, et al. A randomized trial of rescue angioplasty versus a conservative approach for failed fibrinolysis in ST-segment elevation myocardial infarction: the Middlesbrough Early Revascularization to Limit INfarction (MERLIN) trial. J Am Coll Cardiol. 2004;44:287-96. doi:10.1016/j.jacc.2003.12.059.</mixed-citation><mixed-citation xml:lang="en">Sutton AGC, Campbell PG, Graham R, et al. A randomized trial of rescue angioplasty versus a conservative approach for failed fibrinolysis in ST-segment elevation myocardial infarction: the Middlesbrough Early Revascularization to Limit INfarction (MERLIN) trial. J Am Coll Cardiol. 2004;44:287-96. doi:10.1016/j.jacc.2003.12.059.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Wijeysundera H, Vijayaraghavan R, Nallamothu B, et al. Rescue Angioplasty or Repeat Fibrinolysis After Failed Fibrinolytic Therapy for ST-Segment Myocardial Infarction: A Meta--Analysis of Randomized Trials. JACC. 2007;49(4):422-30. doi:10.1016/j.jacc.2006.09.033.</mixed-citation><mixed-citation xml:lang="en">Wijeysundera H, Vijayaraghavan R, Nallamothu B, et al. Rescue Angioplasty or Repeat Fibrinolysis After Failed Fibrinolytic Therapy for ST-Segment Myocardial Infarction: A Meta--Analysis of Randomized Trials. JACC. 2007;49(4):422-30. doi:10.1016/j.jacc.2006.09.033.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Collet JP, Montalesot G, Le May M, et al. Percutaneous coronary intervention after fibrinolysis: a multiple meta-analyses approach according to the type of strategy. J Am Coll Cardiol. 2006;48:1326-35. doi:10.1016/j.jacc.2006.03.064.</mixed-citation><mixed-citation xml:lang="en">Collet JP, Montalesot G, Le May M, et al. Percutaneous coronary intervention after fibrinolysis: a multiple meta-analyses approach according to the type of strategy. J Am Coll Cardiol. 2006;48:1326-35. doi:10.1016/j.jacc.2006.03.064.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Appleton DL, Abbate A, Biondi-¬Zoccai GGL. Late percutaneous coronary intervention for the totally occluded infarct-¬related artery: a meta-analysis of the effects on cardiac function and remodeling. Catheter Cardiovasc Interv. 2008;71:772-81. doi:10.1002/ccd.21468.</mixed-citation><mixed-citation xml:lang="en">Appleton DL, Abbate A, Biondi-¬Zoccai GGL. Late percutaneous coronary intervention for the totally occluded infarct-¬related artery: a meta-analysis of the effects on cardiac function and remodeling. Catheter Cardiovasc Interv. 2008;71:772-81. doi:10.1002/ccd.21468.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Borgia F, Goodman SG, Halvorsen S, et al. Early routine percutaneous coronary intervention after fibrinolysis vs. standard therapy in ST-segment elevation myocardial infarction: a meta-analysis. Eur Heart J. 2010;31(17):2156-69. doi:10.1093/eurheartj/ehq204.</mixed-citation><mixed-citation xml:lang="en">Borgia F, Goodman SG, Halvorsen S, et al. Early routine percutaneous coronary intervention after fibrinolysis vs. standard therapy in ST-segment elevation myocardial infarction: a meta-analysis. Eur Heart J. 2010;31(17):2156-69. doi:10.1093/eurheartj/ehq204.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">D’Souza SP, Mamas MA, Fraser DG, et al. Routine early coronary angioplasty versus ischaemia-¬guided angioplasty after thrombolysis in acute ST-elevation myocardial infarction: a meta-analysis. Eur Heart J. 2011;32(8):972-82. doi:10.1093/eurheartj/ehq398.</mixed-citation><mixed-citation xml:lang="en">D’Souza SP, Mamas MA, Fraser DG, et al. Routine early coronary angioplasty versus ischaemia-¬guided angioplasty after thrombolysis in acute ST-elevation myocardial infarction: a meta-analysis. Eur Heart J. 2011;32(8):972-82. doi:10.1093/eurheartj/ehq398.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Hochman JS, Lamas GA, Buller CE, et al.; Occluded Artery Trial Investigators. Coronary intervention for persistent occlusion after myocardial infarction. N Engl J Med. 2006; 355(23):2395-407. doi:10.1056/NEJMoa066139.</mixed-citation><mixed-citation xml:lang="en">Hochman JS, Lamas GA, Buller CE, et al.; Occluded Artery Trial Investigators. Coronary intervention for persistent occlusion after myocardial infarction. N Engl J Med. 2006; 355(23):2395-407. doi:10.1056/NEJMoa066139.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Schömig A, Mehilli J, Antoniucci D, et al. Mechanical Reperfusion in Patients With Acute Myocardial Infarction Presenting More Than 12 Hours From Symptom Onset: A Randomized Controlled Trial. JAMA. 2005;293(23):2865-72. doi:10.1001/jama.293.23.2865.</mixed-citation><mixed-citation xml:lang="en">Schömig A, Mehilli J, Antoniucci D, et al. Mechanical Reperfusion in Patients With Acute Myocardial Infarction Presenting More Than 12 Hours From Symptom Onset: A Randomized Controlled Trial. JAMA. 2005;293(23):2865-72. doi:10.1001/jama.293.23.2865.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Nadrepepa G, Kastrati A, Mehilli J, et al. Mechanical reperfusion and long-term mortality in patients with acute myocardial infarction presenting 12 to 48 hours from onset of symptoms. JAMA. 2009;301(5):487-8. doi:10.1001/jama.2009.32.</mixed-citation><mixed-citation xml:lang="en">Nadrepepa G, Kastrati A, Mehilli J, et al. Mechanical reperfusion and long-term mortality in patients with acute myocardial infarction presenting 12 to 48 hours from onset of symptoms. JAMA. 2009;301(5):487-8. doi:10.1001/jama.2009.32.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Bouisset F, Gerbaud E, Bataille V, et al. Percutaneous myocardial revascularization in latepresenting patients with STEMI. J Am Coll Cardiol. 2021;78:1291-305. doi:10.1016/j.jacc.2021.07.039.</mixed-citation><mixed-citation xml:lang="en">Bouisset F, Gerbaud E, Bataille V, et al. Percutaneous myocardial revascularization in latepresenting patients with STEMI. J Am Coll Cardiol. 2021;78:1291-305. doi:10.1016/j.jacc.2021.07.039.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Busk M, Kaltoft A, Nielsen SS, et al. Infarct size and myocardial salvage after primary angioplasty in patients presenting with symptoms for &lt;12 h vs. 12-72 h. Eur Heart J. 2009;30:1322-30. doi:10.1093/eurheartj/ehp113.</mixed-citation><mixed-citation xml:lang="en">Busk M, Kaltoft A, Nielsen SS, et al. Infarct size and myocardial salvage after primary angioplasty in patients presenting with symptoms for &lt;12 h vs. 12-72 h. Eur Heart J. 2009;30:1322-30. doi:10.1093/eurheartj/ehp113.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Ioannidis JP, Katritsis DG. Percutaneous coronary intervention for late reperfusion after myocardial infarction in stable patients. Am Heart J. 2007;154(6):1065-71. doi:10.1016/j.ahj.2007.07.049.</mixed-citation><mixed-citation xml:lang="en">Ioannidis JP, Katritsis DG. Percutaneous coronary intervention for late reperfusion after myocardial infarction in stable patients. Am Heart J. 2007;154(6):1065-71. doi:10.1016/j.ahj.2007.07.049.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Menon V, Pearte CA, Buller CE, et al. Lack of benefit from percutaneous intervention of persistently occluded infarct arteries after the acute phase of myocardial infarction is time independent: insights from Occluded Artery Trial. Eur Heart J. 2009;30(2):183-91. doi:10.1093/eurheartj/ehn486.</mixed-citation><mixed-citation xml:lang="en">Menon V, Pearte CA, Buller CE, et al. Lack of benefit from percutaneous intervention of persistently occluded infarct arteries after the acute phase of myocardial infarction is time independent: insights from Occluded Artery Trial. Eur Heart J. 2009;30(2):183-91. doi:10.1093/eurheartj/ehn486.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Wald DS, Morris JK, Wald NJ, et al. &amp; PRAMI Investigators. Randomized trial of preventive angioplasty in myocardial infarction. The New England journal of medicine. 2013;369(12):1115-23. doi:10.1056/NEJMoa1305520.</mixed-citation><mixed-citation xml:lang="en">Wald DS, Morris JK, Wald NJ, et al. &amp; PRAMI Investigators. Randomized trial of preventive angioplasty in myocardial infarction. The New England journal of medicine. 2013;369(12):1115-23. doi:10.1056/NEJMoa1305520.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Engstrøm T, Kelbæk H, Helqvist S, et al. Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI 3 — PRIMULTI): an open-label, randomised controlled trial. Lancet. 2015;386:665-71. doi:10.1016/s0140-6736(15)60648-1.</mixed-citation><mixed-citation xml:lang="en">Engstrøm T, Kelbæk H, Helqvist S, et al. Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI 3 — PRIMULTI): an open-label, randomised controlled trial. Lancet. 2015;386:665-71. doi:10.1016/s0140-6736(15)60648-1.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Smits PC, Abdel-¬Wahab M, Neumann FJ, et al. Fractional flow reserve-¬guided multivessel angioplasty in myocardial infarction. N Engl J Med. 2017;376:1234-44. doi:10.1056/NEJMoa1701067.</mixed-citation><mixed-citation xml:lang="en">Smits PC, Abdel-¬Wahab M, Neumann FJ, et al. Fractional flow reserve-¬guided multivessel angioplasty in myocardial infarction. N Engl J Med. 2017;376:1234-44. doi:10.1056/NEJMoa1701067.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Mehta SR, Wang J, Wood DA, et al.; COMPLETE Trial Investigators. Complete Revascularization vs Culprit Lesion-¬Only Percutaneous Coronary Intervention for Angina--Related Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction: Results From the COMPLETE Randomized Clinical Trial. JAMA cardiology. 2022;7(11):1091-9. doi:10.1001/jamacardio.2022.3032.</mixed-citation><mixed-citation xml:lang="en">Mehta SR, Wang J, Wood DA, et al.; COMPLETE Trial Investigators. Complete Revascularization vs Culprit Lesion-¬Only Percutaneous Coronary Intervention for Angina--Related Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction: Results From the COMPLETE Randomized Clinical Trial. JAMA cardiology. 2022;7(11):1091-9. doi:10.1001/jamacardio.2022.3032.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Gershlick AH, Khan JN, Kelly DJ, et al. Randomized trial of complete versus lesion-only revascularization in patients undergoing primary percutaneous coronary intervention for STEMI and multivessel disease: the CvLPRIT trial. J Am Coll Cardiol. 2015;65:963-72. doi:10.1016/j.jacc.2014.12.038.</mixed-citation><mixed-citation xml:lang="en">Gershlick AH, Khan JN, Kelly DJ, et al. Randomized trial of complete versus lesion-only revascularization in patients undergoing primary percutaneous coronary intervention for STEMI and multivessel disease: the CvLPRIT trial. J Am Coll Cardiol. 2015;65:963-72. doi:10.1016/j.jacc.2014.12.038.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Chin CT, L’Allier P, Neumann FJ, et al. The Compare-¬Acute trial of fractional flow reserve--guided multivessel angioplasty in myocardial infarction. EuroIntervention: journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 2017;13(5):e613 e616. doi:10.4244/EIJV13I5A96.</mixed-citation><mixed-citation xml:lang="en">Chin CT, L’Allier P, Neumann FJ, et al. The Compare-¬Acute trial of fractional flow reserve--guided multivessel angioplasty in myocardial infarction. EuroIntervention: journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 2017;13(5):e613 e616. doi:10.4244/EIJV13I5A96.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Diletti R, den Dekker WK, Bennett J; BIOVASC Investigators. Immediate versus staged complete revascularisation in patients presenting with acute coronary syndrome and multivessel coronary disease (BIOVASC): a prospective, open-label, non-inferiority, randomised trial. Lancet. 2023;401(10383):1172-82. doi:10.1016/S0140-6736(23)00351-3.</mixed-citation><mixed-citation xml:lang="en">Diletti R, den Dekker WK, Bennett J; BIOVASC Investigators. Immediate versus staged complete revascularisation in patients presenting with acute coronary syndrome and multivessel coronary disease (BIOVASC): a prospective, open-label, non-inferiority, randomised trial. Lancet. 2023;401(10383):1172-82. doi:10.1016/S0140-6736(23)00351-3.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Biscaglia S, Guiducci V, Escaned J, et al.; FIRE Trial Investigators. Complete or Culprit-Only PCI in Older Patients with Myocardial Infarction. N Engl J Med. 2023;389(10):88998. doi:10.1056/NEJMoa2300468.</mixed-citation><mixed-citation xml:lang="en">Biscaglia S, Guiducci V, Escaned J, et al.; FIRE Trial Investigators. Complete or Culprit-Only PCI in Older Patients with Myocardial Infarction. N Engl J Med. 2023;389(10):88998. doi:10.1056/NEJMoa2300468.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Reichlin T, Twerenbold R, Reiter M, et al. Introduction of high-sensitivity troponin assays: impact on myocardial infarction incidence and prognosis. Am J Med. 2012;125:1205-13. doi:10.1016/j.amjmed.2012.07.015.</mixed-citation><mixed-citation xml:lang="en">Reichlin T, Twerenbold R, Reiter M, et al. Introduction of high-sensitivity troponin assays: impact on myocardial infarction incidence and prognosis. Am J Med. 2012;125:1205-13. doi:10.1016/j.amjmed.2012.07.015.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Сhapman AR, Lee KK, McAllister DA, et al. Association of High-¬Sensitivity Cardiac Troponin I Concentration With Cardiac Outcomes in Patients With Suspected Acute Coronary Syndrome. JAMA. 2017;318:1913-24. doi:10.1001/jama.2017.17488.</mixed-citation><mixed-citation xml:lang="en">Сhapman AR, Lee KK, McAllister DA, et al. Association of High-¬Sensitivity Cardiac Troponin I Concentration With Cardiac Outcomes in Patients With Suspected Acute Coronary Syndrome. JAMA. 2017;318:1913-24. doi:10.1001/jama.2017.17488.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Mueller C, Giannitsis E, Mockel M, et al., Biomarker Study Group of the ESC ACCA. Rapid rule out of acute myocardial infarction: novel biomarker-¬based strategies. Eur Heart J Acute Cardiovasc Care. 2017;6:218-22. doi:10.1177/2048872616653229.</mixed-citation><mixed-citation xml:lang="en">Mueller C, Giannitsis E, Mockel M, et al., Biomarker Study Group of the ESC ACCA. Rapid rule out of acute myocardial infarction: novel biomarker-¬based strategies. Eur Heart J Acute Cardiovasc Care. 2017;6:218-22. doi:10.1177/2048872616653229.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Pickering JW, Than MP, Cullen L, et al. Rapid Rule-out of Acute Myocardial Infarction With a Single HighSensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis. Ann Intern Med. 2017;166:715-3724. doi:10.7326/M16-2562.</mixed-citation><mixed-citation xml:lang="en">Pickering JW, Than MP, Cullen L, et al. Rapid Rule-out of Acute Myocardial Infarction With a Single HighSensitivity Cardiac Troponin T Measurement Below the Limit of Detection: A Collaborative Meta-analysis. Ann Intern Med. 2017;166:715-3724. doi:10.7326/M16-2562.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Miller-¬Hodges E, Anand A, Shah ASV, et al. High-¬Sensitivity Cardiac Troponin and the Risk Stratification of Patients With Renal Impairment Presenting With Suspected Acute Coronary Syndrome. Circulation. 2018;137:425-35. doi:10.1161/CIRCULATIONAHA.117.030320.</mixed-citation><mixed-citation xml:lang="en">Miller-¬Hodges E, Anand A, Shah ASV, et al. High-¬Sensitivity Cardiac Troponin and the Risk Stratification of Patients With Renal Impairment Presenting With Suspected Acute Coronary Syndrome. Circulation. 2018;137:425-35. doi:10.1161/CIRCULATIONAHA.117.030320.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Townsend N, Wilson L, Bhatnagar P, et al. Cardiovascular disease in Europe: epidemiological update 2016. European Heart Journal. 2016;37(42):3232-45. doi:10.1093/eurheartj/ehw334.</mixed-citation><mixed-citation xml:lang="en">Townsend N, Wilson L, Bhatnagar P, et al. Cardiovascular disease in Europe: epidemiological update 2016. European Heart Journal. 2016;37(42):3232-45. doi:10.1093/eurheartj/ehw334.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Abu-¬Assi E, López-¬López A, González-¬Salvado V, et al. The Risk of Cardiovascular Events After an Acute Coronary Event Remains High, Especially During the First Year, Despite Revascularization. Revista Espanola de Cardiologia. 2016;69(1):11-8. doi:10.1016/j.rec.2015.06.015.</mixed-citation><mixed-citation xml:lang="en">Abu-¬Assi E, López-¬López A, González-¬Salvado V, et al. The Risk of Cardiovascular Events After an Acute Coronary Event Remains High, Especially During the First Year, Despite Revascularization. Revista Espanola de Cardiologia. 2016;69(1):11-8. doi:10.1016/j.rec.2015.06.015.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Bouisset F, Ruidavets J-B, Dallongeville J, et al. Comparison of Short- and Long-¬Term Prognosis between ST-Elevation and Non-¬ST-Elevation Myocardial Infarction. Journal of Clinical Medicine. 2021;10(2):180. doi:10.3390/jcm10020180.</mixed-citation><mixed-citation xml:lang="en">Bouisset F, Ruidavets J-B, Dallongeville J, et al. Comparison of Short- and Long-¬Term Prognosis between ST-Elevation and Non-¬ST-Elevation Myocardial Infarction. Journal of Clinical Medicine. 2021;10(2):180. doi:10.3390/jcm10020180.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
