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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2025-6398</article-id><article-id custom-type="edn" pub-id-type="custom">EIOXYH</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-6398</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРОБЛЕМНАЯ СТАТЬЯ</subject></subj-group></article-categories><title-group><article-title>Роль пальце-плечевого индекса в оценке  клинического статуса пациента</article-title><trans-title-group xml:lang="en"><trans-title>Role of the toe-brachial index in assessing the patient’s clinical status</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7463-9259</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олейников</surname><given-names>В. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Oleynikov</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, зав. кафедрой "Терапия"</p><p>Пенза</p></bio><bio xml:lang="en"><p>Penza</p></bio><email xlink:type="simple">v.oleynikof@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6136-6394</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минджи</surname><given-names>Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Mindzhi</surname><given-names>D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заместитель директора отделения гериатрической сердечно-сосудистой медицины и заместитель директора отделения общей медицины</p><p>Сиань</p></bio><bio xml:lang="en"><p>Xi’an</p></bio><email xlink:type="simple">dingmingge@xjtu.edu.cn</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4266-5900</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeeva</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры "Терапия"</p><p>Пенза</p><p> </p></bio><bio xml:lang="en"><p>Penza</p></bio><email xlink:type="simple">eliseeva.iv1@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-9855-2948</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулакова</surname><given-names>Э. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulakova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>м.н.с. научной лаборатории «Комплексные методы изучения биомеханики и электрофизиологии сердечно-сосудистой системы»</p><p>Пенза</p></bio><bio xml:lang="en"><p>Penza</p></bio><email xlink:type="simple">el_oley@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-3002-5815</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павленко</surname><given-names>К. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlenko</surname><given-names>K. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры «Терапия»</p><p>Пенза</p></bio><bio xml:lang="en"><p>Penza</p></bio><email xlink:type="simple">ksenia-p2017@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Пензенский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Вторая аффилированная больница Сианьского университета Цзяотун</institution><country>Китай</country></aff><aff xml:lang="en"><institution>The Second Affiliated Hospital of Xi’an Jiaotong University</institution><country>China</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2025</year></pub-date><volume>30</volume><issue>9S</issue><issue-title>Обзоры литературы, мнения по проблеме</issue-title><fpage>6398</fpage><lpage>6398</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Олейников В.Э., Минджи Д., Авдеева И.В., Кулакова Э.В., Павленко К.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Олейников В.Э., Минджи Д., Авдеева И.В., Кулакова Э.В., Павленко К.И.</copyright-holder><copyright-holder xml:lang="en">Oleynikov V.E., Mindzhi D., Avdeeva I.V., Kulakova E.V., Pavlenko K.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/6398">https://russjcardiol.elpub.ru/jour/article/view/6398</self-uri><abstract><p>Хотя понятие "поражение органов-мишеней" употребляется, прежде всего, относительно диагностики артериальной гипертензии, очевидно, что сосуды страдают при более широком спектре заболеваний. За последние 30 лет артериальная ригидность переместилась из области чисто научных интересов в клинические рекомендации. Для оценки поражения органов-мишеней широко используется лодыжечно-плечевой индекс. При ряде состояний (сахарный диабет, хроническая болезнь почек, особенно в терминальную стадию почечной недостаточности и при проведении программного гемодиализа) развивается выраженный медиакальциноз стенок артерий. В результате артерии становятся некомпрессируемыми, что приводит к ложно завышенным значениям лодыжечно-плечевого индекса (&gt;1,4). Сосуды пальцев ног менее восприимчивы к формированию сосудистой ригидности, что делает пальце-плечевой индекс доступной альтернативой в подобной ситуации. В литературном обзоре освещена история развития пальце-плечевого индекса как метода исследования, а также предиктивная значимость и перспективы дальнейшего применения. Его использование открывает возможности для углубления и расширения представлений о патогенезе широкого спектра заболеваний, поиска и апробации методов коррекции и разработки эффективных способов профилактики.</p></abstract><trans-abstract xml:lang="en"><p>Although the term "target organ damage" is used primarily in relation to the diagnosis of hypertension, the fact that vessels are involved in a wider range of diseases is beyond doubt. Over the past 30 years, arterial stiffness has moved from the area of scientific interest to clinical guidelines. The ankle-brachial index is widely used to assess target organ damage. In a number of conditions (diabetes, chronic kidney disease, especially in the end-stage renal failure and hemodialysis), severe medial calcification of the arterial walls develops. As a result, the arteries become non-compressible, which leads to falsely elevated ankle-brachial index (&gt;1,4). Toe vessels are less susceptible to vascular stiffness, which makes the toe-brachial index an accessible alternative in such a situation. The literature review highlights the history of toe-brachial index development as a research method, as well as the predictive value and prospects for further application. Its use offers opportunities for deepening and expanding understanding of the pathogenesis of a wide range of diseases, searching for and testing correction methods and developing effective prevention methods.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная ригидность</kwd><kwd>лодыжечно-плечевой индекс</kwd><kwd>пальце-плечевой индекс</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial stiffness</kwd><kwd>ankle-brachial index</kwd><kwd>toe-brachial index</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Грант РНФ 25-25-00352 "Исследование нелипидобусловленной дисфункции эндотелия с оценкой корригирующего влияния статинов".</funding-statement><funding-statement xml:lang="en">Grant of the Russian Science Foundation 25-25-00352 "Study of non-lipid-mediated endothelial dysfunction with an assessment of statin effect".</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кобалава Ж. 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