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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2023-564</article-id><article-id custom-type="edn" pub-id-type="custom">NGNQKU</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-5640</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СТРЕСС В ПОПУЛЯЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>STRESS IN THE POPULATION</subject></subj-group></article-categories><title-group><article-title>«Биология и биография»: к вопросу о биосоциальном патогенезе неинфекционной патологии</article-title><trans-title-group xml:lang="en"><trans-title>Biology and biography: revisiting the biosocial pathogenesis of non-communicable diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2925-0102</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таратухин</surname><given-names>Е. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Taratukhin</surname><given-names>E. О.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Таратухин Евгений Олегович — кандидат медицинских наук, доцент, магистр психологии, магистр культурологии, зав. кафедрой биоэтики и международного медицинского права ЮНЕСКО МФ</p><p>Москва</p><p>SPIN-код: 9566-9557</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">cardio03@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО Российский национальный исследовательский медицинский университет им. Н. И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>12</day><month>10</month><year>2023</year></pub-date><volume>28</volume><issue>11</issue><fpage>5640</fpage><lpage>5640</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Таратухин Е.О., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Таратухин Е.О.</copyright-holder><copyright-holder xml:lang="en">Taratukhin E.О.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/5640">https://russjcardiol.elpub.ru/jour/article/view/5640</self-uri><abstract><p>Современное представление о заболевании как ситуации, событии, всё больше включает в себя социальную сторону наряду с биологической. Хотя по-прежнему биомедицинская сторона проблемы доминирует, такие факторы, как приверженность, принятие решений и дача информированного согласия либо отказ, психосоциальные аспекты этиопатогенеза и другие не биологические компоненты развития болезни, становятся частью оказания помощи. Безусловно, социальная сторона вопроса учитывалась и раньше; до развития научной медицины она была преобладающей. Но в современном контексте развитие гуманитарных и социальных наук, нейронауки, психологии даёт возможность учитывать биографический нарратив личности пациента как неотъемлемую часть взаимоотношений врач-пациент. На стыке "биологического" и "биографического"в природе заболевания находится ряд факторов — таких как одиночество, стресс, социально-направленные эмоции, — которые овеществляют, воплощают (reify, enact) социальное Я человека в соматическую патологию либо в соматическое здоровье. Проблема соединения гуманитарного и естественно-научного знания очень сложна ввиду принципиальной разницы способов изучения, однако для современной медицины такое соединение совершенно необходимо.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>The modern idea of a disease as a situation, an event, increasingly includes the social side along with the biological one. Although the biomedical side of the problem still dominates, factors such as adherence, decision-making and informed consent or refusal, psychosocial aspects of etiology and pathogenesis and other non-biological disease components become part of care provision. Of course, the social side was predominant before the development of evidencebased medicine. But in the modern context, the development of the humanities and social sciences, as well as neuroscience and psychology, makes it possible to take into account the biographical narrative of the patient’s personality as an integral part of the doctor-patient relationship. At the intersection of "biological" and "biographical" in the disease nature there are a number of factors, such as loneliness, stress, emotions, that reify, enact a person’s social self into somatic pathology or somatic health. The problem of combining humanities and natural science knowledge is very complex due to the fundamental difference in the methods of study, but for modern medicine such a connection is absolutely necessary.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>междисциплинарность</kwd><kwd>психология здоровья</kwd><kwd>одиночество</kwd><kwd>энактивизм</kwd><kwd>коммуникация врач-пациент</kwd><kwd>медицинское право</kwd><kwd>нарративная медицина</kwd></kwd-group><kwd-group xml:lang="en"><kwd>interdisciplinarity</kwd><kwd>health psychology</kwd><kwd>loneliness</kwd><kwd>enactivism</kwd><kwd>doctorpatient communication</kwd><kwd>medical law</kwd><kwd>narrative medicine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Costa F. Big data in biomedicine. Drug discovery today. 2014;19(4):433-40. doi:10.1016/j.drudis.2013.10.012.</mixed-citation><mixed-citation xml:lang="en">Costa F. Big data in biomedicine. Drug discovery today. 2014;19(4):433-40. doi:10.1016/j.drudis.2013.10.012.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">McFarlane A. Medical Humanities. In: Herbrechter S, Callus I, Rossini M, Grech M, de Bruin-Molé M, John Müller C. (eds) Palgrave Handbook of Critical Posthumanism. Palgrave Macmillan, Cham. 2022. doi:10.1007/978-3-030-42681-1_53-1. ISBN: 978-3-030-42681-1.</mixed-citation><mixed-citation xml:lang="en">McFarlane A. Medical Humanities. In: Herbrechter S, Callus I, Rossini M, Grech M, de Bruin-Molé M, John Müller C. (eds) Palgrave Handbook of Critical Posthumanism. Palgrave Macmillan, Cham. 2022. doi:10.1007/978-3-030-42681-1_53-1. ISBN: 978-3- 030-42681-1.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Horwitz RI, Singer BH, Hayes-Conroy A, et al. Biosocial pathogenesis. Psychother Psychosom. 2022;91:73-7. doi:10.1159/000521567.</mixed-citation><mixed-citation xml:lang="en">Horwitz RI, Singer BH, Hayes-Conroy A, et al. Biosocial pathogenesis. Psychother Psychosom. 2022;91:73-7. doi:10.1159/000521567.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Евстифеева С. Е., Шальнова С. А., Макарова Ю. К. и др. Ассоциируется ли уровень тревоги и депрессии в популяции со смертностью населения? По данным исследования ЭССЕ-РФ. Кардиоваскулярная терапия и профилактика. 2021;20(5):3009. doi:10.15829/1728-8800-2021-3009.</mixed-citation><mixed-citation xml:lang="en">Evstifeeva SE, Shalnova SA, Makarova YuK, et al. Is the population level of anxiety and depression associated with mortality? Data from the ESSE-RF study. Cardiovascular Therapy and Prevention. 2021;20(5):3009. (In Russ.) doi:10.15829/1728-8800-2021-3009.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Родионова Ю. В. Neighborhood environment — формирование здоровье-сберегающей экосистемы человека. Кардиоваскулярная терапия и профилактика. 2021;20(6):3061. doi:10.15829/1728-8800-2021-3061.</mixed-citation><mixed-citation xml:lang="en">Rodionova YuV. Neighborhood environment — formation of a health-saving human ecosystem. Cardiovascular Therapy and Prevention. 2021;20(6):3061. (In Russ.) doi:10.15829/1728-8800-2021-3061.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Paul E, Bu F, Fancourt D. Loneliness and Risk for Cardiovascular Disease: Mechanisms and Future Directions. Curr Cardiol Rep. 2021;23:68. doi:10.1007/s11886-021-01495-2.</mixed-citation><mixed-citation xml:lang="en">Paul E, Bu F, Fancourt D. Loneliness and Risk for Cardiovascular Disease: Mechanisms and Future Directions. Curr Cardiol Rep. 2021;23:68. doi:10.1007/s11886-021-01495-2.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Li W, Wang Z, Syed S, et al. Chronic social isolation signals starvation and reduces sleep in Drosophila. Nature. 2021;597:239-44. doi:10.1038/s41586-021-03837-0.</mixed-citation><mixed-citation xml:lang="en">Li W, Wang Z, Syed S, et al. Chronic social isolation signals starvation and reduces sleep in Drosophila. Nature. 2021;597:239-44. doi:10.1038/s41586-021-03837-0.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Cole SW. The conserved transcriptional response to adversity. Curr Opin Behav Sci. 2019;28:31-7. doi:10.1016/j.cobeha.2019.01.008.</mixed-citation><mixed-citation xml:lang="en">Cole SW. The conserved transcriptional response to adversity. Curr Opin Behav Sci. 2019;28:31-7. doi:10.1016/j.cobeha.2019.01.008.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Sharma T, Padala RP, Mehta LJ. Loneliness and Social Isolation: Determinants of Cardiovascular Outcomes. Current Cardiology Reviews. 2021;17(6):e051121190873. doi:10.2174/1573403X17666210129101845.</mixed-citation><mixed-citation xml:lang="en">Sharma T, Padala RP, Mehta LJ. Loneliness and Social Isolation: Determinants of Cardiovascular Outcomes. Current Cardiology Reviews. 2021;17(6):e051121190873. doi:10.2174/1573403X17666210129101845.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hawkins-Elder H, Milfont TL, Hammond MD, Sibley CG. Who are the lonely? A typology of loneliness in New Zealand. Australian &amp; New Zealand Journal of Psychiatry. 2018;52(4):357-64. doi:10.1177/0004867417718944.</mixed-citation><mixed-citation xml:lang="en">Hawkins-Elder H, Milfont TL, Hammond MD, Sibley CG. Who are the lonely? A typology of loneliness in New Zealand. Australian &amp; New Zealand Journal of Psychiatry. 2018;52(4):357-64. doi:10.1177/0004867417718944.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Read C, Szokolszky A. Ecological Psychology and Enactivism: Perceptually-Guided Action vs. Sensation-Based Enaction. Frontiers in Psychology. 2020;11:1270. doi:10.3389/fpsyg.2020.01270.</mixed-citation><mixed-citation xml:lang="en">Read C, Szokolszky A. Ecological Psychology and Enactivism: Perceptually-Guided Action vs. Sensation-Based Enaction. Frontiers in Psychology. 2020;11:1270. doi:10.3389/fpsyg.2020.01270.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Таратухин Е. О. Личность больного: междисциплинарный подход в работе с кардиологической патологией. Российский кардиологический журнал. 2014;(9):22-5. doi:10.15829/1560-4071-2014-9-22-25.</mixed-citation><mixed-citation xml:lang="en">Taratukhin EO. Patient’s personality: an interdisciplinary approach to cardiovascular pathology. Russian Journal of Cardiology. 2014;(9):22-5. (In Russ.) doi:10.15829/1560-4071-2014-9-22-25.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Таратухин Е. О., Кудинова М. А., Шайдюк О. Ю. и др. Человекоцентрированное интервью как инструмент клинической работы с больными инфарктом миокарда. Кардиоваскулярная терапия и профилактика. 2017;16(1):34- 9. doi:10.15829/1728-8800-2017-1-34-39.</mixed-citation><mixed-citation xml:lang="en">Taratukhin EO, Kudinova MA, Shaydyuk ОYu, et al. Person-centered interview as a tool for clinical work in myocardial infarction setting. Cardiovascular Therapy and Prevention. 2017;16(1):34-9. (In Russ.) doi:10.15829/1728-8800-2017-1-34-39.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Таратухин Е. О. Иерархия факторов риска. Российский кардиологический журнал. 2017;(9):28-33. doi:10.15829/1560-4071-2017-9-28-33.</mixed-citation><mixed-citation xml:lang="en">Taratukhin ЕО. Risk factors hierarchy. Russian Journal of Cardiology. 2017;(9):28-33. (In Russ.) doi:10.15829/1560-4071-2017-9-28-33.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
