russjcardiolРоссийский кардиологический журналRussian Journal of Cardiology1560-40712618-7620«SILICEA-POLIGRAF» LLC10.15829/1560-4071-2016-2-75-83russjcardiol-520Research ArticleКЛИНИКА И ФАРМАКОТЕРАПИЯGUIDELINES FOR THE PRACTITIONERПРОДОЛЖИТЕЛЬНОСТЬ ДВОЙНОЙ АНТИТРОМБОЦИТАРНОЙ ТЕРАПИИ. ФАКТЫ И ПРЕДПОЛОЖЕНИЯTIMELINE FOR THE DOUBLE ANTIPLATELET THERAPY. FACTS AND SUGGESTIONSБарбарашО. Л.BarbarashO. L.

д.м.н., профессор, директор, зав. кафедрой кардиологии и сердечно-сосудистой хирургии,

Кемерово

Kemerovo

olb61@mail.ruКашталапВ. В.KashtalapV. V.

д.м.н., зав. лабораторией патофизиологии мультифокального атеросклероза, доцент кафедры кардиологии и сердечно-сосудистой хирургии,

Кемерово

Kemerovo

v_kash@mail.ruФГБНУ Научно-исследовательский институт комплексных проблем сердечно- сосудистых заболеваний; ГБОУ ВПО Кемеровская государственная медицинская академия Минздрава РоссииРоссияResearch Institute for Complex Issues of Cardiovascular Diseases; Kemerovo State Medical Academy of the Ministry of HealthRussian Federation20162802201602РОССИЙСКИЙ КАРДИОЛОГИЧЕСКИЙ ЖУРНАЛ7583Copyright © Барбараш О.Л., Кашталап В.В., 20162016Барбараш О.Л., Кашталап В.В.Barbarash O.L., Kashtalap V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://russjcardiol.elpub.ru/jour/article/view/520

В обзорной статье представлены современные данные, касающиеся одного из ключевых вопросов современной кардиологии — продолжительности двойной антитромбоцитарной терапии (ДАТТ) у пациентов с различными формами ишемической болезни сердца. Проведен анализ актуальных клинических рекомендаций, касающихся этого вопроса, освещены результаты недавних клинических исследований и проведенных мета-анализов. На основании результатов международных исследований постулируется необходимость тщательной оценки пользы и риска как пролонгирования, так и укорочения ДАТТ и представляются возможные показания для таких изменений сроков 12-месячной ДАТТ.

The review article provides with recent data on the crucial cardiology problems — duration of double antiplatelet therapy (DAPT) in patients with different types of ischemic heart disease. The analysis is provided of actual clinical guidelines on this issue, the results of recent clinical trials are highlighted, as of metaanalyses. Based on the results of international trials, the necessity postulated of thorough assessment of risk and safety for either prolongation or shortening of DAPT, and some possible indications provided for these changes in 12-month DAPT.

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The authors declare that there are no conflicts of interest present.