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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2022-5195</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-5195</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СОВЕТ ЭКСПЕРТОВ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERT CONSENSUS</subject></subj-group></article-categories><title-group><article-title>Воздействие на автономную регуляцию сердечно-сосудистой системы как стратегическое направление лечения артериальной гипертензии, нарушений ритма и сердечной недостаточности</article-title><trans-title-group xml:lang="en"><trans-title>Influence on the autonomic cardiovascular system regulation in the treatment of hypertension, arrhythmias and heart failure</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2929-0980</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шляхто</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shlyakhto</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, академик РАН, генеральный директор, Президент Российского кардиологического общества, Заслуженный деятель науки РФ, главный кардиолог Санкт-Петербурга и Северо-Западного федерального округа</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">zvartau_ne@almazovcentre.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8169-7812</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конради</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Konradi</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, заведующая кафедрой кардиологии, начальник службы анализа и перспективного планирования</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6533-5950</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Звартау</surname><given-names>Н. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvartau</surname><given-names>N. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, старший научный сотрудник НИЛ патогенеза и терапии артериальной гипертензии, заместитель генерального директора по работе с регионами, начальник управления по реализации федеральных проектов, доцент кафедры внутренних болезней Института медицинского образования</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">zvartau_ne@almazovcentre.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5981-1754</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Недогода</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nedogoda</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Заведующая кафедрой терапии и эндокринологии факультета усовершенствования врачей</p><p>Волгоград</p></bio><bio xml:lang="en"><p>Volgograd</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1943-1137</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лопатин</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lopatin</surname><given-names>Yu. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, заведующая кафедрой кардиологии, сердечно-соcудистой и торакальной хирургии Института НМФО, заведующая кардиологическим отделением</p><p>Волгоград</p></bio><bio xml:lang="en"><p>Volgograd</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0139-5177</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ситникова</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Sitnikova</surname><given-names>M. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, руководитель научно-исследовательского отдела сердечной недостаточности, ведущий научный сотрудник лаборатории высокотехнологичных методов лечения сердечной недостаточности, профессор кафедры внутренних болезней Института медицинского образования</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6553-9141</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailov</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, заместитель директора Института сердца и сосудов по научной работе, руководитель НИЛ нейромодуляции, профессор кафедры сердечно-сосудистой хирургии Института медицинского образования</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8788-0076</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор кафедры терапии факультетской с курсом кардиологии, эндокринологии и функциональной диагностики с клиникой, директор НИИ сердечно-сосудистых заболеваний научно-клинического исследовательского центра</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4510-6197</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галявич</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Galyavich</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, вице-президент Российского кардиологического общества, заведующая кафедрой кардиологии</p><p>Казань</p></bio><bio xml:lang="en"><p>Kazan</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6453-2976</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дупляков</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Duplyakov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, заместитель главного врача по медицинской части</p><p>Самара</p></bio><bio xml:lang="en"><p>Samara</p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6611-9165</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саласюк</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Salasyuk</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, доцент кафедры внутренних болезней</p><p>Волгоград</p></bio><bio xml:lang="en"><p>Volgograd</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5129-9944</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галагудза</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Galagudza</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, член-корр. РАН, директор Института экспериментальной медицины, главный научный сотрудник НИО микроциркуляции и метаболизма миокарда, заведующий кафедрой патологии Института медицинского образования</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Национальный медицинский исследовательский центр им. В.А. Алмазова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО Волгоградский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Volgograd State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО Волгоградский государственный медицинский университет Минздрава России;&#13;
ГБУЗ Волгоградский областной клинический кардиологический</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Volgograd State Medical University;&#13;
Volgograd Regional Clinical Cardiology Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВО Казанский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ГБУЗ Самарский областной клинический кардиологический диспансер</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara Regional Clinical Cardiology Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>25</day><month>08</month><year>2022</year></pub-date><volume>27</volume><issue>9</issue><fpage>5195</fpage><lpage>5195</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шляхто Е.В., Конради А.О., Звартау Н.Э., Недогода С.В., Лопатин Ю.М., Ситникова М.Ю., Михайлов Е.Н., Баранова Е.И., Галявич А.С., Дупляков Д.В., Саласюк А.С., Галагудза М.М., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Шляхто Е.В., Конради А.О., Звартау Н.Э., Недогода С.В., Лопатин Ю.М., Ситникова М.Ю., Михайлов Е.Н., Баранова Е.И., Галявич А.С., Дупляков Д.В., Саласюк А.С., Галагудза М.М.</copyright-holder><copyright-holder xml:lang="en">Shlyakhto E.V., Konradi A.O., Zvartau N.E., Nedogoda S.V., Lopatin Y.M., Sitnikova M.Y., Mikhailov E.N., Baranova E.I., Galyavich A.S., Duplyakov D.V., Salasyuk A.S., Galagudza M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/5195">https://russjcardiol.elpub.ru/jour/article/view/5195</self-uri><abstract><p>Сердечно-сосудистые заболевания широко распространены и являются ведущей причиной смертности населения в большинстве стран мира, несмотря на создание и совершенствование стратегий снижения сердечно-сосудистого риска. Существенная роль в развитии и эволюции сердечно-сосудистых заболеваний принадлежит повышенной активности симпатической нервной системы, поэтому методы воздействия на нее являются актуальными для профилактики и терапии кардиоваскулярной патологии. В статье рассмотрены современные подходы к интервенционной и медикаментозной регуляции автономной нервной системы и нейромодуляции в профилактике и лечении артериальной гипертензии, хронической сердечной недостаточности, тахиаритмий, и отражено консолидированное экспертное мнение по данным вопросам.</p></abstract><trans-abstract xml:lang="en"><p>Cardiovascular diseases are widespread and are the leading death cause in most countries, despite the creation and improvement of strategies to reduce cardiovascular risk. A significant role in the development and evolution of cardiovascular diseases belongs to sympathetic nervous system hyperactivity, and therefore the methods of effecting it are relevant for the prevention and treatment of cardiovascular pathology. The article discusses modern approaches to interventional and conservative regulation of the autonomic nervous system and neuromodulation in the prevention and treatment of hypertension, heart failure, tachyarrhythmias, as well as reflects a conjoint expert judgment on these issues.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нейромодуляция</kwd><kwd>артериальная гипертензия</kwd><kwd>хроническая сердечная недостаточность</kwd><kwd>тахиаритмии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>neuromodulation</kwd><kwd>hypertension</kwd><kwd>heart failure</kwd><kwd>tachyarrhythmias</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO. The top 10 causes of death [Electronic resource]. URL: https://www.who.int/newsroom/fact-sheets/detail/the-top-10-causes-of-death (accessed: 23.08.2021).</mixed-citation><mixed-citation xml:lang="en">WHO. 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