russjcardiolРоссийский кардиологический журналRussian Journal of Cardiology1560-40712618-7620«SILICEA-POLIGRAF» LLC10.15829/1560-4071-2022-5147russjcardiol-5147Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWЭлектрокардиографические параметры и особенности желудочковых нарушений ритма при различных фенотипических формах аритмогенной кардиомиопатии в педиатрической популяции: систематический обзор и метаанализElectrocardiographic parameters and features of ventricular arrhythmias in various arrhythmogenic cardiomyopathy forms in the pediatric population: a systematic review and meta-analysishttps://orcid.org/0000-0003-1751-1424АлексееваД. Ю.AlekseevaD. Yu.

Кандидат медицинских наук, научный сотрудник НИО неизвестных, редких и генетически обусловленных заболеваний НЦМУ "Центр персонализированной медицины"; врач-кардиолог консультативного отделения КДЦ.

Санкт-Петербург, Пушкин

St. Petersburg, Pushkin

nik135@inbox.ruhttps://orcid.org/0000-0003-4720-9023КофейниковаО. А.KofeynikovaO. А.

Младший научный сотрудник НИО неизвестных, редких и генетически обусловленных заболеваний НЦМУ "Центр персонализированной медицины", врач-детский кардиолог отделения кардиологии и медицинской реабилитации детского лечебно-реабилитационного корпуса Института перинатологии и педиатрии.

Санкт-Петербург

St. Petersburg

kofeolyaa@gmail.comhttps://orcid.org/0000-0003-2583-0599МараповД. И.MarapovD. I.

Кандидат медицинских наук, доцент кафедры общественного здоровья, экономики и управления здравоохранением.

Казань

Kazan

damirov@list.ruhttps://orcid.org/0000-0001-7336-4102ВасичкинаЕ. С.VasichkinaE. S.

Доктор медицинских наук, руководитель НИЦ неизвестных, редких и генетически-обусловленных заболеваний НЦМУ "Центр персонализированной медицины", профессор кафедры детский болезней Института медицинского образования.

Санкт-Петербург

St. Petersburg

Vasichkinalena@mail.ruФГБУ НМИЦ им. В.А. Алмазова Минздрава России; ФГБУ НМИЦ детской травматологии и ортопедии им. Г.И. Турнера Минздрава РоссииРоссияAlmazov National Medical Research Center; Turner National Medical Research Center for Сhildren›s Orthopedics and Trauma SurgeryRussian FederationФГБУ НМИЦ им. В.А. Алмазова Минздрава РоссииРоссияAlmazov National Medical Research CenterRussian FederationФГБОУ ВО Казанский ГМУ Минздрава РоссииРоссияKazan State Medical UniversityRussian Federation202214092022273SОбразование51475147Copyright © Алексеева Д.Ю., Кофейникова О.А., Марапов Д.И., Васичкина Е.С., 20222022Алексеева Д.Ю., Кофейникова О.А., Марапов Д.И., Васичкина Е.С.Alekseeva D.Y., Kofeynikova O.А., Marapov D.I., Vasichkina E.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://russjcardiol.elpub.ru/jour/article/view/5147

Аритмогенная кардиомиопатия (АКМП) — редкое наследственное заболевание, характеризующееся развитием жизнеопасных желудочковых аритмий и нарушением систолической функции желудочков вследствие фиброзножирового замещения миокарда. В настоящее время для диагностики данного заболевания предложены критерии Task Force 2010 и критерии Падуи. Однако, несмотря на многопараметрический подход, есть определенные ограничения представленных алгоритмов выявления заболевания, особенно у детей. Проведение таких высокотехнологичных методов диагностики, как эндомиокардиальная биопсия и магнитно-резонансная томография, крайне затруднено в педиатрической популяции. В связи с этим изучение и применение электрокардиографических параметров становится крайне актуальным у детей. Кроме того, отсутствуют данные об особенностях желудочковых аритмий при АКМП в педиатрической популяции. В систематическом обзоре с метаанализом изучили особенности желудочковых нарушений ритма и электрокардиографических параметров при различных формах АКМП.

Arrhythmogenic cardiomyopathy (ACM) is a rare genetic disease characterized by the development of life-threatening ventricular arrhythmias and impaired ventricular systolic function due to fibrofatty infiltration of the myocardium. Currently, the Task Force 2010 criteria and the Padua criteria are proposed for the diagnosis of this disease. However, despite the multiparametric approach, there are certain limitations of the presented algorithms for disease establishment, especially in children. Carrying out such high-tech diagnostic methods as endomyocardial biopsy and magnetic resonance imaging is extremely difficult in the pediatric population. In this regard, the study and application of electrocardiography becomes extremely relevant in children. In addition, there are no data on the features of ventricular arrhythmias in ACM in the pediatric population. In this systematic review with meta-analysis, we studied the features of ventricular arrhythmias and electrocardiographic parameters in various ACM types.

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The authors declare that there are no conflicts of interest present.