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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2022-5085</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-5085</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Сравнительный анализ показателей деформации миокарда левого желудочка больных хронической сердечной недостаточностью ишемического и неишемического генеза</article-title><trans-title-group xml:lang="en"><trans-title>Comparative analysis of left ventricular strain parameters in patients with heart failure of ischemic and non-ischemic genesis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1294-9646</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Илов</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilov</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николай Николаевич Илов — кандидат медицинских наук, доцент кафедры сердечно-сосудистой хирургии, врач сердечно-сосудистый хирург отделения хирургического лечения сложных нарушений ритма сердца и электрокардиостимуляции.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Nikolay Nikolaevich Ilov - Associate Professor of the department of cardiovascular surgery, Cardiovascular surgeon, M.D.</p><p>Astrakhan</p></bio><email xlink:type="simple">nikolay.ilov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2400-8045</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стомпель</surname><given-names>Д. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Stompel</surname><given-names>D. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Динара Рафаиловна Стомпель — заведующий отделением функциональной диагностики.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Dinara Rafailovna Stompel - head of the department of functional diagnostics.</p><p>Astrakhan</p></bio><email xlink:type="simple">dinasto71@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6998-8406</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бойцов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Boytsov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Анатольевич Бойцов — академик РАН, профессор, доктор медицинских наук, генеральный директор.</p><p>Москва</p></bio><bio xml:lang="en"><p>SergeyAnatolievich Boytsov - Director of the  National Medical Research Center of Cardiology of the RBoytsovussian Ministry of Healthcare, Moscow, MD, PhD, Professor, Academician of the Russian Academy of Sciences.</p><p>Moscow</p></bio><email xlink:type="simple">prof.boytsov@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4476-5174</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пальникова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Palnikova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Олеся Викторовна Пальникова — врач-кардиолог отделения хирургического лечения сложных нарушений ритма сердца и электрокардиостимуляции.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Olesya Viktorovna Palnikov - cardiologist of the department of surgical treatment of complex arrhythmias and pacemaker implantations.</p><p>Astrakhan</p></bio><email xlink:type="simple">palnicovaolesya@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5722-9883</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нечепуренко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nechepurenko</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анатолий Анатольевич Нечепуренко — кандидат медицинских наук, заведующий отделением хирургического лечения сложных нарушений ритма сердца и электрокардиостимуляции.</p><p>Астрахань</p></bio><bio xml:lang="en"><p>Anatoly Anatolievich Nechepurenko - head of the department of surgical treatment of complex arrhythmias and pacemaker implantations, M.D..</p><p>Astrakhan</p></bio><email xlink:type="simple">vestik@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Астраханский ГМУ Минздрава России; ФГБУ Федераль ный центр сердечно-сосудистой хирургии Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Astrakhan State Medical University; Federal Center for Cardiovascular Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ Национальный медицинский исследовательский центр кардиологии им. акад. Е.И. Чазова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>E.I. Chazov National Medical Research Center of Cardiology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ Федеральный центр сердечно-сосудистой хирургии Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Center for Cardiovascular Surgery</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>04</day><month>01</month><year>2023</year></pub-date><volume>27</volume><issue>12</issue><fpage>5085</fpage><lpage>5085</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Илов Н.Н., Стомпель Д.Р., Бойцов С.А., Пальникова О.В., Нечепуренко А.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Илов Н.Н., Стомпель Д.Р., Бойцов С.А., Пальникова О.В., Нечепуренко А.А.</copyright-holder><copyright-holder xml:lang="en">Ilov N.N., Stompel D.R., Boytsov S.A., Palnikova O.V., Nechepurenko A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/5085">https://russjcardiol.elpub.ru/jour/article/view/5085</self-uri><abstract><sec><title>Цель</title><p>Цель. Провести сравнительный анализ деформационных показателей миокарда левого желудочка (ЛЖ), определяемых методом двухмерного стрейна, у больных хронической сердечной недостаточности (ХСН) с фракцией выброса (ФВ) ЛЖ ≤35% в зависимости от причины ХСН.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование было включено 133 больных ХСН NYHA 3-4 функционального класса с ФВ ЛЖ ≤35%, принимающих оптимальную медикаментозную терапию. Исходя из причины ХСН, были сформированы 2 группы больных ишемической кардиомиопатией (ИКМП), n=70, и неишемической кардиомиопатией (НКМП), n=63, которым проводилась speckletracking эхокардиография.</p></sec><sec><title>Результаты</title><p>Результаты. У всех пациентов, включенных в исследование, были выявлены значительные сдвиги параметров продольной деформации в большинстве сегментов миокарда, максимально выраженные в базальных и средних отделах ЛЖ. При сравнительном анализе значений максимального систолического продольного стрейна худшие деформационные характеристики у больных ИКМП были выявлены в апикальных (р=0,008), а у пациентов с НКМП — в базальных сегментах ЛЖ (р=0,046). Изучаемые группы имели сопоставимые значения показателей глобального продольного и циркулярного стрейна ЛЖ (р=0,26; р=0,67; соответственно).</p></sec><sec><title>Заключение</title><p>Заключение. Группы больных ХСН ишемического и неишемического генеза, несмотря на сопоставимые значения ФВ ЛЖ, различаются по характеру распределения снижения локальной продольной деформации отдельных сегментов ЛЖ. Худшие деформационные характеристики у больных ИКМП выявляются в апикальных сегментах, а у пациентов с НКМП — в базальных сегментах ЛЖ.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To carry out a comparative analysis of left ventricular (LV) strain parameters, determined by the two-dimensional strain imaging in patients with heart failure (HF) with LV ejection fraction (EF) ≤35%, depending on the origin of HF.</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 133 patients with NYHA class 3-4 HF with LVEF ≤35%, taking optimal therapy. Based on the HF origin, 2 following groups of patients were formed: ischemic cardiomyopathy (ICM) (n=70), nonischemic cardiomyopathy (NICM) (n=63). All patients underwent speckle-tracking echocardiography.</p></sec><sec><title>Results</title><p>Results. All patients included in the study showed significant alterations in longitudinal strain parameters in most myocardial segments, most pronounced in the basal and middle parts of the LV. Comparative analysis of the peak systolic longitudinal strain showed the worst characteristics in patients with ICM were found in the apical segments (p=0,008), and in patients with NICM, in the basal segments of the LV (p=0,046). The studied groups had comparable LV global longitudinal and circumferential strain (p=0,26; p=0,67; respectively).</p></sec><sec><title>Conclusion</title><p>Conclusion. Groups of patients with HF of ischemic and non-ischemic origin, despite comparable LVEF values, differ in the distribution of the decrease in local longitudinal strain of LV segments. The worst strain characteristics in patients with ICM and NICM are detected in LV apical and basal segments, respectively.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>деформация миокарда</kwd><kwd>левый желудочек</kwd></kwd-group><kwd-group xml:lang="en"><kwd>heart failure</kwd><kwd>myocardial strain</kwd><kwd>left ventricle</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">McDonagh TA, Metra M, Adamo M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2021;42:3599-726. doi:10.1093/eurheartj/ehab368.</mixed-citation><mixed-citation xml:lang="en">McDonagh TA, Metra M, Adamo M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. 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