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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2021-4656</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-4656</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Сердечно-сосудистый статус и динамика эхокардиографических показателей лиц, перенесших COVID-19 пневмонию, через три месяца после выписки из стационара</article-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular status and echocardiographic changes in survivors of COVID-19 pneumonia three months after hospital discharge</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4993-056X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Криночкин</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Krinochkin</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, заведующий отделением УЗИ, старший научный сотрудник лаборатории инструментальной диагностики научного отдела инструментальных методов исследования</p><p>Томск</p></bio><bio xml:lang="en"><p>Tomsk</p></bio><email xlink:type="simple">cardiojournal@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1436-8853</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярославская</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yaroslavskaya</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, врач ультразвуковой диагностики, заведующая лабораторией инструментальной диагностики научного отдела инструментальных методов исследования, ведущий научный сотрудник лаборатории инструментальной диагностики научного отдела инструментальных методов исследования</p><p>Томск</p></bio><bio xml:lang="en"><p>Tomsk</p></bio><email xlink:type="simple">yaroslavskayae@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4325-2633</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Широков</surname><given-names>Н. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Shirokov</surname><given-names>N. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, младший научный сотрудник лаборатории инструментальной диагностики научного отдела инструментальных методов исследования</p><p>Томск</p></bio><bio xml:lang="en"><p>Tomsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5061-9210</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гультяева</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Gultyaeva</surname><given-names>E. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, зав. консультативным отделением</p><p>Томск</p></bio><bio xml:lang="en"><p>Tomsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4787-8342</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Криночкина</surname><given-names>И. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Krinochkina</surname><given-names>I. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кандидат медицинских наук, доцент кафедры терапии с курсами эндокринологии, ультразвуковой и функциональной диагностики института непрерывного профессионального развития, главный внештатный специалист — пульмонолог Департамента здравоохранения Тюменской области; врач-пульмонолог</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Tyumen</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8146-459X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коровина</surname><given-names>И. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Korovina</surname><given-names>I. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Врач-пульмонолог</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Tyumen</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8160-7060</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамарина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamarina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Врач-стажер</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Tomsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3928-8238</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осокина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Osokina</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Студент</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Tyumen</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6595-8816</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельников</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnikov</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Заведующий отделением лучевой диагностики</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Tyumen</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2768-4890</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трифанова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trifanova</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лаборант-исследователь лаборатории инструментальной диагностики научного отдела инструментальных методов исследования</p><p>Томск</p></bio><bio xml:lang="en"><p>Tomsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0858-2933</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горбатенко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorbatenko</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лаборант-исследователь лаборатории инструментальной диагностики научного отдела инструментальных методов исследования</p><p>Томск</p></bio><bio xml:lang="en"><p>Tomsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6251-4179</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петелина</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Petelina</surname><given-names>T. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, заместитель директора по научной работе</p><p>Томск</p></bio><bio xml:lang="en"><p>Tomsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тюменский кардиологический научный центр, Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen Cardiology Research Center, Tomsk National Research Medical Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО Тюменский ГМУ Минздрава России; &#13;
ГБУЗ ТО “ОКБ № 1”</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University; &#13;
City Clinical Hospital № 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ ТО “ОКБ № 1”</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>City Clinical Hospital № 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО Тюменский ГМУ Минздрава России</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ГБУЗ ТО “ОКБ № 2”</institution><country>Russian Federation</country></aff><aff xml:lang="en"><institution>City Clinical Hospital № 2</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>03</day><month>09</month><year>2021</year></pub-date><volume>26</volume><issue>9</issue><fpage>4656</fpage><lpage>4656</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Криночкин Д.В., Ярославская Е.И., Широков Н.Е., Гультяева Е.П., Криночкина И.Р., Коровина И.О., Мамарина А.В., Осокина Н.А., Мельников Н.Н., Трифанова Т.А., Горбатенко Е.А., Петелина Т.И., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Криночкин Д.В., Ярославская Е.И., Широков Н.Е., Гультяева Е.П., Криночкина И.Р., Коровина И.О., Мамарина А.В., Осокина Н.А., Мельников Н.Н., Трифанова Т.А., Горбатенко Е.А., Петелина Т.И.</copyright-holder><copyright-holder xml:lang="en">Krinochkin D.V., Yaroslavskaya E.I., Shirokov N.E., Gultyaeva E.P., Krinochkina I.R., Korovina I.O., Mamarina A.V., Osokina N.A., Melnikov N.N., Trifanova T.A., Gorbatenko E.A., Petelina T.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/4656">https://russjcardiol.elpub.ru/jour/article/view/4656</self-uri><abstract><p>Новая коронавирусная инфекция (COVID-19) влияет на работу всех органов и систем. Сегодня актуальным является изучение влияния COVID-19 на сердечно-сосудистую систему, в т.ч. на показатели эхокардиографии (ЭхоКГ) после перенесенного заболевания, особенно, его осложненного течения.</p><sec><title>Цель</title><p>Цель. Изучить частоту симптомов, сердечно-сосудистой патологии и динамику показателей ЭхоКГ у лиц, перенесших доказанную пневмонию COVID-19, через 3 мес. после выписки из стационара.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследование включено 106 пациентов, перенесших доказанную пневмонию COVID-19. Пациенты прошли комплексное клиническое обследование в ходе госпитализации и через 3 мес. ± 2 нед. после выписки из стационара. Средний возраст обследованных 47±16 лет (от 19 до 84 лет), 49% женщин.</p></sec><sec><title>Результаты</title><p>Результаты. Через 3 мес. после выписки из стационара персистирование симптоматики сохранялось у 86% обследованных. Отмечалась достоверная динамика средних показателей ЭхоКГ: уменьшение конечно-диастолического и конечно-систолического, а также ударного объема левого желудочка (113,8±26,8 мл vs 93,5±29,4 мл; 37,7±13,0 мл vs 31,3±14,2 мл; 77,2±17,8 мл vs 62,2±18,7 мл, соответственно, все р&lt; 0,001). Передне-задний размер правого желудочка и диаметр ствола легочной артерии в динамике уменьшились (26,0 [24,0-29,3] мм vs 25,0 [23,0-27,0] мм, р=0,004; 21,7±3,6 мм vs 18,7±2,5 мм, р&lt; 0,001), так же как систолическое давление в легочной артерии, определенное по градиенту трикуспидальной регургитации (28,0 [25,0-32,25] мм рт.ст. vs 21,5 [17,0-25,0] мм рт.ст.). Уменьшился объем (42,0 [37,0-50,0] мл vs 31,0 [22,0-36,5] мл, р&lt; 0,001) и максимальная ширина правого предсердия (36,1±4,6 мм vs 34,5±6,5 мм, р=0,023), при этом максимальная длина правого предсердия увеличилась (46,7±6,8 мм vs 48,6±7,1 мм, р=0,021).</p></sec><sec><title>Заключение</title><p>Заключение. У перенесших COVID-19 пневмонию через 3 мес. после выписки жалобы сохранялись в 86% случаев. Сердечно-сосудистые заболевания выявлены у 52% обследованных, в т.ч. артериальная гипертония у 48,1%, ишемическая болезнь сердца у 15,1%. В динамике по сравнению с данными госпитализации отмечалось улучшение показателей ЭхоКГ, выражающееся преимущественно в уменьшении нагрузки на правые отделы сердца.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title> </title><p> </p><p>Coronavirus disease 2019 (COVID-19) affects the function of all organs and systems. Today, studying the effect of COVID-19 on cardiovascular system, including on echocardiographic characteristics, is relevant.</p></sec><sec><title>Aim</title><p>Aim. To study the prevalence of symptoms, cardiovascular disease and changes in echocardiographic data in persons after documented COVID-19 pneumonia 3 months after discharge from the hospital.</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 106 patients after documented COVID-19 pneumonia. The patients underwent a comprehensive examination during hospitalization and 3 months±2 weeks after discharge from the hospital. The mean age of participants was 47±16 years (19-84 years); 49% of subjects were women.</p></sec><sec><title>Results</title><p>Results. Three months after hospital discharge, the symptoms persisted in 86% of examined patients. There were significant echocardiographic changes as follows: a decrease in LV end-diastolic, end-systolic and stroke volume (113,8±26,8 ml vs 93,5±29,4 ml; 37,7±13,0 ml vs 31,3±14,2 ml; 77,2±17,8 ml vs 62,2±18,7 ml, respectively, p&lt;0,001 for all). The right ventricular anteroposterior dimension and the pulmonary trunk diameter decreased over time (26,0 [24,0-29,3] mm vs 25,0 [23,0-27,0] mm, p=0,004; 21,7±3,6 mm vs 18,7±2,5 mm, p&lt;0,001), the same as the pulmonary artery systolic pressure, estimated by tricuspid regurgitation gradient (28,0 [25,0-32,25] mm Hg vs 21,5 [17,0-25,0] mm Hg). The right atrial volume (42,0 [37,0-50,0] m&gt;&lt;0,001), the same as the pulmonary artery systolic pressure, estimated by tricuspid regurgitation gradient (28,0 [25,0-32,25] mm Hg vs 21,5 [17,0-25,0] mm Hg). The right atrial volume (42,0 [37,0-50,0] ml vs 31,0 [22,0-36,5] ml, p&lt;0,001) a&gt;&lt;0,001) and maximum width (36,1±4,6 mm vs 34,5±6,5 mm, p=0,023) decreased, while the right atrial maximum length increased (46,7±6,8 mm vs 48,6±7,1 mm, p=0,021).</p></sec><sec><title>Conclusion</title><p>Conclusion. In survivors of COVID-19 pneumonia three months after hospital discharge, complaints persisted in 86% of cases. Cardiovascular diseases were detected in 52% of participants, including hypertension in 48,1% and coronary artery disease in 15,1%. Compared with in-hospital data, the echocardiographic characteristics improved, which was expressed mainly in a decrease in right heart load.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19 пневмония</kwd><kwd>эхокардиография</kwd><kwd>правый желудочек</kwd><kwd>правое предсердие</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19 pneumonia</kwd><kwd>echocardiography</kwd><kwd>right ventricle</kwd><kwd>right atrium</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dweck MR, Bularga А, Hahn RT, et al. Global evaluation of echocardiography in patients with COVID-19. 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