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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2020-3985</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-3985</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ И ИССЛЕДОВАТЕЛЬСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL AND INVESTIGATIVE MEDICINE</subject></subj-group></article-categories><title-group><article-title>Распространённость гериатрических синдромов у лиц в возрасте старше 65 лет:  первые результаты российского эпидемиологического исследования ЭВКАЛИПТ</article-title><trans-title-group xml:lang="en"><trans-title>Prevalence of geriatric syndromes in persons over 65 years: the first results of the EVCALIPT study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4193-688X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачёва</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkacheva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор, директор</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">tkacheva@rgnkc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6021-7864</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьёва</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorob’eva</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., заведующая лабораторией сердечно-сосудистого старения</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">natalyavorobjeva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1628-5093</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котовская</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotovskaya</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор, заместитель директора по научной работе</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">kotovskaya@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0795-8225</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Остроумова</surname><given-names>О. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostroumova</surname><given-names>O. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор, заведующая кафедрой терапии и полиморбидной патологии</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">ostroumova.olga@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3091-7904</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черняева</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernyaeva</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м. н., врач-терапевт</p><p>Москва</p></bio><email xlink:type="simple">Pilya.ru@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7670-2947</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Силютина</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Silyutina</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м. н., доцент кафедры физической и реабилитационной медицины, гериатрии ИДПО</p><p>Воронеж</p></bio><bio xml:lang="en"/><email xlink:type="simple">marinad57@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8462-7270</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., доцент, заведующий кафедрой физической и реабилитационной медицины, гериатрии ИДПО</p><p>Воронеж</p></bio><bio xml:lang="en"/><email xlink:type="simple">alex307207@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6921-3002</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тестова</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Testova</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры физической и реабилитационной медицины, гериатрии ИДПО</p><p>Воронеж</p></bio><bio xml:lang="en"/><email xlink:type="simple">sveta.testova2015@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7266-707X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овчарова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovcharova</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. э. н., проректор</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">lovcharova@hse.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6623-6815</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селезнева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Selezneva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. э. н., старший научный сотрудник</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">evselezneva@hse.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО Российский национальный исследовательский медицинский университет им. Н. И. Пирогова Минздрава России — ОСП Российский геронтологический научно-клинический центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Clinical and Research Center of Gerontology, Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ДПО Российская медицинская академия непрерывного профессионального образования Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ Госпиталь для ветеранов войн №2 ДЗМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Hospital for War Veterans № 2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО Воронежский государственный медицинский университет им. Н. Н. Бурденко Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Burdenko Voronezh State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Национальный исследовательский университет Высшая школа экономики</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research University Higher School of Economics</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>08</day><month>08</month><year>2020</year></pub-date><volume>25</volume><issue>10</issue><fpage>3985</fpage><lpage>3985</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ткачёва О.Н., Воробьёва Н.М., Котовская Ю.В., Остроумова О.Д., Черняева М.С., Силютина М.В., Чернов А.В., Тестова С.Г., Овчарова Л.Н., Селезнева Е.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Ткачёва О.Н., Воробьёва Н.М., Котовская Ю.В., Остроумова О.Д., Черняева М.С., Силютина М.В., Чернов А.В., Тестова С.Г., Овчарова Л.Н., Селезнева Е.В.</copyright-holder><copyright-holder xml:lang="en">Tkacheva O.N., Vorob’eva N.M., Kotovskaya Y.V., Ostroumova O.D., Chernyaeva M.S., Silyutina M.V., Chernov A.V., Testova S.G., Ovcharova L.N., Selezneva E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/3985">https://russjcardiol.elpub.ru/jour/article/view/3985</self-uri><abstract><sec><title>Цель</title><p>Цель. Изучить распространённость гериатрических синдромов и оценить их взаимосвязи с синдромом старческой астении (СА) у лиц в возрасте ≥65 лет, проживающих в регионах Российской Федерации с различными демографическими, климатическими и социально-экономическими характеристиками.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Обследовали 664 пациента в возрасте 65-107 лет (средний возраст 79±9 лет; 25% мужчин), проживающих в Москве (n=365) и Воронеже (n=299). Всем пациентам выполнили комплексную гериатрическую оценку, которая состояла из двух этапов: анкетирования по специально разработанному опроснику и объективного обследования.</p></sec><sec><title>Результаты</title><p>Результаты. Распространённость синдрома СА составила 66,4%, в том числе у лиц в возрасте 65-74 года – 47,4%, 75-84 года – 71,1% и ≥85 лет – 82,8% (р для тренда &lt;0,001). Синдром СА был ассоциирован с возрастом (отношение шансов (ОШ) 2,36; 95% доверительный интервал (ДИ) 1,89-2,93; р &lt;0,001) и женским полом (ОШ 1,52; 95% ДИ 1,06-2,18; р=0,024). Пациенты с синдромом СА имели более низкий социально-экономический статус. Также выявлены тесные ассоциации СА с другими гериатрическими синдромами (когнитивные нарушения, депрессия, дефициты зрения и слуха, недержание мочи, падения, высокий риск падений, базовая и функциональная зависимость в повседневной жизни, мальнутриция) с ОШ от 1,32 до 7,22.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the prevalence of geriatric syndromes and assess their relationship with senile asthenia in persons aged ³65 years living in Russian regions with different demographic, climatic and socio-economic characteristics.</p></sec><sec><title>Material and methods</title><p>Material and methods. We examined 664 patients aged 65-107 years (mean age, 79±9 years; men, 25%) living in Moscow (n=365) and Voronezh (n=299). All patients underwent a comprehensive geriatric examination, which consisted of two stages: a survey with original questionnaire and an objective examination.</p></sec><sec><title>Results</title><p>Results. The prevalence of senile asthenia was 66,4%, including 47,4% in people aged 65-74, 71,1% — 75-84 years, and 82,8% — ³85 years (p for trend &lt;0,001). Senile asthenia was associated with age (odds ratio (OR), 2,36; 95% confidence interval (CI), 1,89-2,93; p&lt;0,001) and female sex (OR, 1,52; 95% CI 1,06-2,18; p=0,024). Patients with senile asthenia had a lower socioeconomic status. Also, close associations of senile asthenia with other geriatric syndromes (dementia, depression, vision and hearing impairment, incontinence, falls, high risk of falls, functional decline, failure to thrive) with OR from 1,32 to 7,22 were revealed.</p></sec><sec><title>Conclusion</title><p>Conclusion. The first results of the EVCALIPT study indicate a high incidence of senile asthenia in persons aged ³65 years and its close association with other geriatric syndromes and socio-economic factors.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гериатрический синдром</kwd><kwd>старческая астения</kwd><kwd>эпидемиологическое исследование</kwd><kwd>пожилой пациент</kwd></kwd-group><kwd-group xml:lang="en"><kwd>geriatric syndrome</kwd><kwd>senile asthenia</kwd><kwd>epidemiological study</kwd><kwd>elderly patient</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках государственного задания ФГАОУ ВО “РНИМУ им. Н. И. 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