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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2020-3868</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-3868</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРОБЛЕМНАЯ СТАТЬЯ</subject></subj-group></article-categories><title-group><article-title>Имплантируемый кардиовертер-дефибриллятор: принятие решения об отключении у пациентов с терминальной хронической сердечной недостаточностью</article-title><trans-title-group xml:lang="en"><trans-title>Implantable cardioverter defibrillator: decision-making on turning off in patients with end-stage heart failure</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0507-096X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>В. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>V. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедева Виктория Кимовна — доктор медицинских наук, ведущий научный сотрудник, научно-исследовательская лаборатория интервенционной аритмологии научно-исследовательского отдела аритмологии Института сердца и сосудов, профессор кафедры кардиологии.</p><p>Санкт-Петербург.</p></bio><bio xml:lang="en"><p>St. Petersburg.</p></bio><email xlink:type="simple">lebedevavikt@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2334-1663</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедев Дмитрий Сергеевич — доктор медицинских наук, главный научный сотрудник научно-исследовательский отдел аритмологии Института сердца и сосудов, профессор кафедры сердечно-сосудистой хирургии, профессор РАН.</p><p>Санкт-Петербург.</p></bio><bio xml:lang="en"><p>St. Petersburg.</p></bio><email xlink:type="simple">lebedevdmitry@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Национальный медицинский исследовательский центр им. В.А. Алмазова Минздрава России<country>Россия</country></aff><aff xml:lang="en">Almazov National Medical Research Center<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>25</day><month>05</month><year>2020</year></pub-date><volume>25</volume><issue>9</issue><fpage>3868</fpage><lpage>3868</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лебедева В.К., Лебедев Д.С., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Лебедева В.К., Лебедев Д.С.</copyright-holder><copyright-holder xml:lang="en">Lebedeva V.K., Lebedev D.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/3868">https://russjcardiol.elpub.ru/jour/article/view/3868</self-uri><abstract><p>Применение имплантируемых кардиовертеров-дефибрилляторов стало распространенным стандартным методом первичной и вторичной профилактики внезапной сердечной смерти, продлевающим жизнь пациентам с кардиомиопатиями. В то же время с прогрессированием заболевания, увеличением коморбидности, на последнем этапе жизни наличие данного устройства у пациента может стать причиной принятия непростого решения, когда цели ухода за пациентом смещаются от продления жизни к поддержанию качества жизни пациента. Пациенты с сердечной недостаточностью в конечном итоге умирают из-за прогрессирования основного заболевания, несмотря на доступные в настоящее время прогрессивные технологии. Являются ли определенные поддерживающие жизнь методы лечения все еще уместными в последней фазе жизни — важная тема для дискуссии, поднимаемой в данной статье. “Облегчение” процесса умирания для пациентов с имплантируемыми кардиовертерами-дефибрилляторами представляет непростой для обсуждения вопрос как для пациентов, так и для медицинских работников. В статье описываются различные способы деактивации устройств с функцией дефибрилляции, в зависимости от статуса пациента.</p></abstract><trans-abstract xml:lang="en"><p>The use of implantable cardioverter defibrillators has become a common standard method of primary and secondary prevention of sudden cardiac death, prolonging the life of patients with cardiomyopathy. At the same time, with the disease and comorbidity progression, at the final stages of life, a difficult decision arises to turn off the device due to a shift in priorities from extending life to maintaining its quality. Heart failure patients eventually die due to the progression of the underlying disease, despite currently available advanced technologies. Whether certain lifesustaining treatment methods are still appropriate in the final stages of life is an important topic of discussion in this article. Palliation for patients with implantable cardioverter-defibrillators is a challenging issue for both patients and medical professionals. This article describes the different ways to turn off defibrillation devices based on patient status.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>имплантируемый кардиовертер-дефибриллятор</kwd><kwd>шок</kwd><kwd>терминальный пациент</kwd><kwd>смерть</kwd><kwd>сердечная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>implantable cardioverter defibrillator</kwd><kwd>shock</kwd><kwd>terminal illness patient</kwd><kwd>death</kwd><kwd>heart failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Priori SG, Blomstrom-Lundqvist C, Mazzanti A, et al. 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: Eur Heart J. 2015;36:2793-867. doi:10.1093/eurheartj/ehv316.</mixed-citation><mixed-citation xml:lang="en">Priori SG, Blomstrom-Lundqvist C, Mazzanti A, et al. 2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: Eur Heart J. 2015;36:2793-867. doi:10.1093/eurheartj/ehv316.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Thylen I, Moser DK, Stromberg A, et al. Concerns about implantable cardioverterdefibrillator shocks mediate the relationship between actual shocks and psychological distress. Europace. 2016;18:828-35. doi:10.1093/europace/euv220.</mixed-citation><mixed-citation xml:lang="en">Thylen I, Moser DK, Stromberg A, et al. Concerns about implantable cardioverterdefibrillator shocks mediate the relationship between actual shocks and psychological distress. Europace. 2016;18:828-35. doi:10.1093/europace/euv220.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Bardy GH, Lee KL, Mark DB, et al, for the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J. Med. 2005;352(3):225-37. doi:10.1056/nejmoa043399.</mixed-citation><mixed-citation xml:lang="en">Bardy GH, Lee KL, Mark DB, et al, for the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J. Med. 2005;352(3):225-37. doi:10.1056/nejmoa043399.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Мареев В. Ю., Фомин И. В., Агеев Ф. Т. и др. Клинические рекомендации. Хроническая сердечная недостаточность Журнал Сердечная Недостаточность. 2017;18(1):3-40. doi:10.18087/rhfj.2017.1.2346.</mixed-citation><mixed-citation xml:lang="en">Mareev VYu, Fomin IV, Ageev FT, et al. Clinical recommendations. Chronic heart failure Journal Of Heart Failure. 2017;18(1):3-40. (In Russ.) doi:10.18087/rhfj.2017.1.2346.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Cleland JGF, Hindricks G, Petrie M. The shocking lack of evidence for implantable cardioverter defibrillators for heart failure; with or without cardiac resynchronization. Eur Heart J. 2019;40:2128-30. doi:10.1093/eurheartj/ehz409.</mixed-citation><mixed-citation xml:lang="en">Cleland JGF, Hindricks G, Petrie M. The shocking lack of evidence for implantable cardioverter defibrillators for heart failure; with or without cardiac resynchronization. Eur Heart J. 2019;40:2128-30. doi:10.1093/eurheartj/ehz409.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Padeletti L, Arnar DO, Boncinelli L, et al. EHRA expert consensus statement on the management of cardiovascular implantable electronic devices in patients nearing end of life or requesting withdrawal of therapy. Europace. 2010;12:1480-9. doi:10.1093/europace/euq275.</mixed-citation><mixed-citation xml:lang="en">Padeletti L, Arnar DO, Boncinelli L, et al. EHRA expert consensus statement on the management of cardiovascular implantable electronic devices in patients nearing end of life or requesting withdrawal of therapy. Europace. 2010;12:1480-9. doi:10.1093/europace/euq275.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Greenberg H, Case RB, Moss AJ, et al. Analysis of mortality events in the multicenter automatic defibrillator implantation trial (MADIT-II). JACC. 2004;43(8):1459-65. doi:10.1016/j.jacc.2003.11.038.</mixed-citation><mixed-citation xml:lang="en">Greenberg H, Case RB, Moss AJ, et al. Analysis of mortality events in the multicenter automatic defibrillator implantation trial (MADIT-II). JACC. 2004;43(8):1459-65. doi:10.1016/j.jacc.2003.11.038.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Fromme EK, Lugliani Stewart T, et al. Adverse experiences with implantable defibrillators in Oregon Hospices. Am Hosp Hosp Palliat Care. 2011;28:304-9. doi:10.1177/1049909110390505.</mixed-citation><mixed-citation xml:lang="en">Fromme EK, Lugliani Stewart T, et al. Adverse experiences with implantable defibrillators in Oregon Hospices. Am Hosp Hosp Palliat Care. 2011;28:304-9. doi:10.1177/1049909110390505.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Cubbon RM, Gale CP, Kearney LC, et al. Changing characteristics and mode of death associated with chronic heart failure caused by left ventricular systolic dysfunction: a study across therapeutic eras. Circ Heart Fail. 2011;4:396-403. doi:10.1161/circheartfailure.110.959882.</mixed-citation><mixed-citation xml:lang="en">Cubbon RM, Gale CP, Kearney LC, et al. Changing characteristics and mode of death associated with chronic heart failure caused by left ventricular systolic dysfunction: a study across therapeutic eras. Circ Heart Fail. 2011;4:396-403. doi:10.1161/circheartfailure.110.959882.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Nazarian S, Maisel WH, Miles JS, et al. Impact of implantable cardioverter defibrillators on survival and recurrent hospitalization in advanced heart failure. Am Heart J. 2005;150:955-60. doi:10/1016/j.ahj.2005.01.012.</mixed-citation><mixed-citation xml:lang="en">Nazarian S, Maisel WH, Miles JS, et al. Impact of implantable cardioverter defibrillators on survival and recurrent hospitalization in advanced heart failure. Am Heart J. 2005;150:955-60. doi:10/1016/j.ahj.2005.01.012.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Goldenberg I, Huang DT, Nielsen JC. The role of implantable cardioverter-defibrillators and sudden cardiac death prevention: indications, device selection, and outcome. Eur Heart J. 2019:ehz788. doi:10.1093/eurheartj/ehz788.</mixed-citation><mixed-citation xml:lang="en">Goldenberg I, Huang DT, Nielsen JC. The role of implantable cardioverter-defibrillators and sudden cardiac death prevention: indications, device selection, and outcome. Eur Heart J. 2019:ehz788. doi:10.1093/eurheartj/ehz788.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Goldstein N, Carlson M, Livote E, et al. Brief communication: management of implantable cardioverter-defibrillators in hospice: a nationwide survey. Ann Intern Med. 2010;152(5):296-9. doi:10.7326/0003-4819-152-5-201003020-00007.</mixed-citation><mixed-citation xml:lang="en">Goldstein N, Carlson M, Livote E, et al. Brief communication: management of implantable cardioverter-defibrillators in hospice: a nationwide survey. Ann Intern Med. 2010;152(5):296-9. doi:10.7326/0003-4819-152-5-201003020-00007.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Allen LA, Stevenson LW, Grady KL, et al. Decision Making in Advanced Heart Failure: A Scientific Statement From the American Heart Association. Circulation. 2012;125(15):1928-52. doi:10.1161/CIR.0b013e31824f2173.</mixed-citation><mixed-citation xml:lang="en">Allen LA, Stevenson LW, Grady KL, et al. Decision Making in Advanced Heart Failure: A Scientific Statement From the American Heart Association. Circulation. 2012;125(15):1928-52. doi:10.1161/CIR.0b013e31824f2173.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Stewart GC, Weintraub JR, Pratibhu PP, et al. Patient expectations from implantable defibrillators to prevent death in heart failure. J Card Fail. 2010;16(2):106-13. doi:10.1016/j.cardfail.2009.09.003.</mixed-citation><mixed-citation xml:lang="en">Stewart GC, Weintraub JR, Pratibhu PP, et al. Patient expectations from implantable defibrillators to prevent death in heart failure. J Card Fail. 2010;16(2):106-13. doi:10.1016/j.cardfail.2009.09.003.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Clark AM, Jaarsma T, Strachan P, et al. Effective communication and ethical consent in decisions related to ICDs. Nat Rev Cardiol. 2011;8:694-705. doi:10.1038/nrcardio.2011.101.</mixed-citation><mixed-citation xml:lang="en">Clark AM, Jaarsma T, Strachan P, et al. Effective communication and ethical consent in decisions related to ICDs. Nat Rev Cardiol. 2011;8:694-705. doi:10.1038/nrcardio.2011.101.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
