<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2020-3842</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-3842</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Транссептальное эндоваскулярное протезирование митрального клапана</article-title><trans-title-group xml:lang="en"><trans-title>Transseptal transcatheter mitral valve replacement</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9704-7678</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ганюков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ganyukov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., зав. отделом хирургии сердца и сосудов</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">ganyukov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3882-709X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасов</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasov</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., зав. лабораторией рентгенэндоваскулярной и реконструктивной хирургии сердца и сосудов</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">roman.tarasov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7660-4730</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ганюков</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ganyukov</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач отделения рентгенхирургических методов диагностики и лечения</p><p>Кемерово</p></bio><bio xml:lang="en"><p>Kemerovo</p></bio><email xlink:type="simple">iv_ganyukov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>17</day><month>04</month><year>2020</year></pub-date><volume>25</volume><issue>8</issue><fpage>3842</fpage><lpage>3842</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ганюков В.И., Тарасов Р.С., Ганюков И.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Ганюков В.И., Тарасов Р.С., Ганюков И.В.</copyright-holder><copyright-holder xml:lang="en">Ganyukov V.I., Tarasov R.S., Ganyukov I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/3842">https://russjcardiol.elpub.ru/jour/article/view/3842</self-uri><abstract><p>В обзоре представлены данные о современном направлении в транскатетерном лечении структурной патологии сердца — транссептальном эндоваскулярном протезировании митрального клапана (ТЭМК), которое становится альтернативным методом лечения у больных митральным пороком сердца. Несмотря на то, что трансапикальный транскатетерный доступ технически более простой, транссептальный подход менее инвазивный, подтверждает свою эффективность и прогнозируется как наиболее перспективный. В обзоре описаны актуальность, показания, методология подбора необходимого эндопротеза, этапы вмешательства, осложнения, порядок послеоперационного наблюдения пациентов после ТЭМК. Анализируются результаты публикаций, представляющих ТЭМК. Приводится клинический пример ТЭМК.</p></abstract><trans-abstract xml:lang="en"><p>The review presents current data transseptal transcatheter mitral valve replacement, which is becoming an alternative method of managing mitral valve disease. Despite the fact that the transapical transcatheter approach is technically simpler, the transseptal method is less invasive. It has confirmed effectiveness and is predicted to be the most promising. The review describes the relevance, indications, methodology for selecting the required endoprosthesis, stages of procedure, complications, and the postoperative follow-up of patients. The results of publications on transseptal transcatheter mitral valve replacement are analyzed. A case report is given.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>транссептальное эндоваскулярное протезирование митрального клапана</kwd><kwd>эндопротез</kwd></kwd-group><kwd-group xml:lang="en"><kwd>transseptal transcatheter mitral valve replacement</kwd><kwd>endoprosthesis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nkomo VT, Gardin JM, Skelton TN, et al. Burden of valvular heart diseases: a populationbased study. Lancet. 2006;368(9540):1005-11. doi:10/1016/S0140-6736(06)69208-8.</mixed-citation><mixed-citation xml:lang="en">Nkomo VT, Gardin JM, Skelton TN, et al. Burden of valvular heart diseases: a populationbased study. Lancet. 2006;368(9540):1005-11. doi:10/1016/S0140-6736(06)69208-8.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Coffey S, Cairns BJ, Iung B. The modern epidemiology of heart valve disease. Heart. 2016;102:75-85. doi:10.1136/heartjnl-2014-307020.</mixed-citation><mixed-citation xml:lang="en">Coffey S, Cairns BJ, Iung B. The modern epidemiology of heart valve disease. Heart. 2016;102:75-85. doi:10.1136/heartjnl-2014-307020.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Baumgartner H, Falk V, Bax JJ, et al. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J. 2017;38(36):2739-91. doi:10.1093/eurheartj/ehx391.</mixed-citation><mixed-citation xml:lang="en">Baumgartner H, Falk V, Bax JJ, et al. 2017 ESC/EACTS Guidelines for the management of valvular heart disease. Eur Heart J. 2017;38(36):2739-91. doi:10.1093/eurheartj/ehx391.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Шарифулин Р. М., Богачев-Прокофьев А. В., Журавлева И. Ю. и др. Результаты транскатетерного протезирования митрального клапана. Российский кардиологический журнал. 2018;23(11):137-44. doi:10.15829/1560-4071-2018-11-137-144.</mixed-citation><mixed-citation xml:lang="en">Sharifulin RM, Bogachev-Prokofiev AV, Zhuravleva IYu, et al. Results of transcatheter mitral valve replacement. Russian Journal of Cardiology. 2018;23(11):137-44. (In Russ.) doi:10.15829/1560-4071-2018-11-137-144.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Paradis JM, Del Trigo M, Puri R, Rodés-Cabau J. Transcatheter Valve-in-Valve and Valvein-Ring for Treating Aortic and Mitral Surgical Prosthetic Dysfunction. J Am Coll Cardiol. 2015;66(18):2019-37. doi:10.1016/j.jacc.2015.09.015.</mixed-citation><mixed-citation xml:lang="en">Paradis JM, Del Trigo M, Puri R, Rodés-Cabau J. Transcatheter Valve-in-Valve and Valvein-Ring for Treating Aortic and Mitral Surgical Prosthetic Dysfunction. J Am Coll Cardiol. 2015;66(18):2019-37. doi:10.1016/j.jacc.2015.09.015.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Vohra HA, Whistance RN, Roubelakis A, et al. Outcome after redo-mitral valve replacement in adult patients: a 10-year single-centre experience. Interact Cardiovasc Thorac Surg. 2012;14:575-9. doi:10.1093/icvts/ivs005.</mixed-citation><mixed-citation xml:lang="en">Vohra HA, Whistance RN, Roubelakis A, et al. Outcome after redo-mitral valve replacement in adult patients: a 10-year single-centre experience. Interact Cardiovasc Thorac Surg. 2012;14:575-9. doi:10.1093/icvts/ivs005.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bourguignon T, Bouquiaux-Stablo AL, Loardi C, et al. Very late outcomes for mitral valve replacement with the Carpentier-Edwards pericardial bioprosthesis: 25-year follow-up of 450 implantations. J Thorac Cardiovasc Surg. 2014;148:2004-11.e1. doi:10.1016/j.jtcvs.2014.02.050.</mixed-citation><mixed-citation xml:lang="en">Bourguignon T, Bouquiaux-Stablo AL, Loardi C, et al. Very late outcomes for mitral valve replacement with the Carpentier-Edwards pericardial bioprosthesis: 25-year follow-up of 450 implantations. J Thorac Cardiovasc Surg. 2014;148:2004-11.e1. doi:10.1016/j.jtcvs.2014.02.050.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Papadopoulos N, Dietrich M, Christodoulou T, et al. Midterm survival after decalcification of the mitral annulus. Ann Thorac Surg. 2009;87:1143-7. doi:10.1016/j.athoracsur.2008.12.041.</mixed-citation><mixed-citation xml:lang="en">Papadopoulos N, Dietrich M, Christodoulou T, et al. Midterm survival after decalcification of the mitral annulus. Ann Thorac Surg. 2009;87:1143-7. doi:10.1016/j.athoracsur.2008.12.041.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Eleid MF, Cabalka AK, Williams MR, et al. Percutaneous Transvenous Transseptal Tra nscatheter Valve Implantation in Failed Bioprosthetic Mitral Valves, Ring Annuloplasty, and Severe Mitral Annular Calcification. JACC Cardiovasc Interv. 2016;9(11):1161-74. doi:10.1016/j.jcin.2016.02.041.</mixed-citation><mixed-citation xml:lang="en">Eleid MF, Cabalka AK, Williams MR, et al. Percutaneous Transvenous Transseptal Tra nscatheter Valve Implantation in Failed Bioprosthetic Mitral Valves, Ring Annuloplasty, and Severe Mitral Annular Calcification. JACC Cardiovasc Interv. 2016;9(11):1161-74. doi:10.1016/j.jcin.2016.02.041.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Eleid MF, Whisenant BK, Cabalka AK, et al. Early Outcomes of Percutaneous Transvenous Transseptal Transcatheter Valve Implantation in Failed Bioprosthetic Mitral Valves, Ring Annuloplasty, and Severe Mitral Annular Calcification. JACC Cardiovasc Interv. 2017;10(19):1932-42. doi:10.1016/j.jcin.2017.08.014.</mixed-citation><mixed-citation xml:lang="en">Eleid MF, Whisenant BK, Cabalka AK, et al. Early Outcomes of Percutaneous Transvenous Transseptal Transcatheter Valve Implantation in Failed Bioprosthetic Mitral Valves, Ring Annuloplasty, and Severe Mitral Annular Calcification. JACC Cardiovasc Interv. 2017;10(19):1932-42. doi:10.1016/j.jcin.2017.08.014.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Yoon SH, Whisenant BK, Bleiziffer S, et al. Outcomes of transcatheter mitral valve replacement for degenerated bioprostheses, failed annuloplasty rings, and mitral annular calcification. Eur Heart J. 2019;40(5):441-51. doi:10.1093/eurheartj/ehy590.</mixed-citation><mixed-citation xml:lang="en">Yoon SH, Whisenant BK, Bleiziffer S, et al. Outcomes of transcatheter mitral valve replacement for degenerated bioprostheses, failed annuloplasty rings, and mitral annular calcification. Eur Heart J. 2019;40(5):441-51. doi:10.1093/eurheartj/ehy590.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Overtchouk P, Piazza N, Granada J, et al. Advances in transcatheter mitral and tricuspid therapies. BMC Cardiovasc Disord. 2020;20(1):1. doi:10.1186/s12872-019-01312-3.</mixed-citation><mixed-citation xml:lang="en">Overtchouk P, Piazza N, Granada J, et al. Advances in transcatheter mitral and tricuspid therapies. BMC Cardiovasc Disord. 2020;20(1):1. doi:10.1186/s12872-019-01312-3.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Webb JG, Murdoch DJ, Boone RH, et al. Percutaneous Transcatheter Mitral Valve Repla cement: First-in-Human Experience With a New Transseptal System. J Am Coll Cardiol. 2019;73(11):1239-46. doi:10.1016/j.jacc.2018.12.065.</mixed-citation><mixed-citation xml:lang="en">Webb JG, Murdoch DJ, Boone RH, et al. Percutaneous Transcatheter Mitral Valve Repla cement: First-in-Human Experience With a New Transseptal System. J Am Coll Cardiol. 2019;73(11):1239-46. doi:10.1016/j.jacc.2018.12.065.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Modine T, Vahl TP, Khalique OK, et al. First-in-Human Implant of the Cephea Transseptal Mitral Valve Replacement System. Circ Cardiovasc Interv. 2019;12(9):e008003. doi:10.1161/CIRCINTERVENTIONS.119.008003.</mixed-citation><mixed-citation xml:lang="en">Modine T, Vahl TP, Khalique OK, et al. First-in-Human Implant of the Cephea Transseptal Mitral Valve Replacement System. Circ Cardiovasc Interv. 2019;12(9):e008003. doi:10.1161/CIRCINTERVENTIONS.119.008003.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Søndergaard L, De Backer O, Franzen OW, et al. First-in-Human Case of Transfemoral CardiAQ Mitral Valve Implantation. Circ Cardiovasc Interv. 2015;8(7):e002135. doi:10.1161/CIRCINTERVENTIONS.115.002135.</mixed-citation><mixed-citation xml:lang="en">Søndergaard L, De Backer O, Franzen OW, et al. First-in-Human Case of Transfemoral CardiAQ Mitral Valve Implantation. Circ Cardiovasc Interv. 2015;8(7):e002135. doi:10.1161/CIRCINTERVENTIONS.115.002135.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Cullen MW, Cabalka AK, Alli OO, et al. Transvenous, antegrade Melody valve-in-valve implantation for bioprosthetic mitral and tricuspid valve dysfunction: a case series in children and adults. J Am Coll Cardiol Intv. 2013;6:598-605.</mixed-citation><mixed-citation xml:lang="en">Cullen MW, Cabalka AK, Alli OO, et al. Transvenous, antegrade Melody valve-in-valve implantation for bioprosthetic mitral and tricuspid valve dysfunction: a case series in children and adults. J Am Coll Cardiol Intv. 2013;6:598-605.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Fassa AA, Himbert D, Brochet E, et al. Transseptal transcatheter mitral valve implantation for severely calcified mitral stenosis. JACC Cardiovasc Interv 2014;7:696-7. doi:10.1016/j.jcin.2013.12.204.</mixed-citation><mixed-citation xml:lang="en">Fassa AA, Himbert D, Brochet E, et al. Transseptal transcatheter mitral valve implantation for severely calcified mitral stenosis. JACC Cardiovasc Interv 2014;7:696-7. doi:10.1016/j.jcin.2013.12.204.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Søndergaard L, Brooks M, Ihlemann N, et al. Transcatheter mitral valve implantation via transapical approach: an early experience. Eur J Cardiothorac Surg. 2015;48(6):873-8. doi:10.1093/ejcts/ezu546</mixed-citation><mixed-citation xml:lang="en">Søndergaard L, Brooks M, Ihlemann N, et al. Transcatheter mitral valve implantation via transapical approach: an early experience. Eur J Cardiothorac Surg. 2015;48(6):873-8. doi:10.1093/ejcts/ezu546</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Ussia GP, Quadri A, Cammalleri V, et al. Percutaneous transfemoral-transseptal implantation of a second-generation CardiAQ mitral valve bioprosthesis: first procedure description and 30-day follow-up. EuroIntervention. 2016;11:1126-31. doi:10.4244/EIJY15M09_01.</mixed-citation><mixed-citation xml:lang="en">Ussia GP, Quadri A, Cammalleri V, et al. Percutaneous transfemoral-transseptal implantation of a second-generation CardiAQ mitral valve bioprosthesis: first procedure description and 30-day follow-up. EuroIntervention. 2016;11:1126-31. doi:10.4244/EIJY15M09_01.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Taramasso M, Gavazzoni M, Nickenig G, Maisano F. Transcatheter mitral repair and re placement: which procedure for which patient? EuroIntervention. 2019;15(10):867-74. doi:10.4244/EIJ-D-19-00743.</mixed-citation><mixed-citation xml:lang="en">Taramasso M, Gavazzoni M, Nickenig G, Maisano F. Transcatheter mitral repair and re placement: which procedure for which patient? EuroIntervention. 2019;15(10):867-74. doi:10.4244/EIJ-D-19-00743.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">De Bonis M, Ferrara D, Taramasso M, et al. Mitral replacement or repair for functional mitral regurgitation in dilated and ischemic cardiomyopathy: is it really the same? Ann Thorac Surg. 2012;94:44-51. doi:10.1016/j.athoracsur.2012.01.047.</mixed-citation><mixed-citation xml:lang="en">De Bonis M, Ferrara D, Taramasso M, et al. Mitral replacement or repair for functional mitral regurgitation in dilated and ischemic cardiomyopathy: is it really the same? Ann Thorac Surg. 2012;94:44-51. doi:10.1016/j.athoracsur.2012.01.047.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Dayan V, Soca G, Cura L, Mestres CA. Similar survival after mitral valve replacement or repair for ischemic mitral regurgitation: a meta-analysis. Ann Thorac Surg. 2014;97:758-65. doi:10.1016/j.athoracsur.2013.10.044.</mixed-citation><mixed-citation xml:lang="en">Dayan V, Soca G, Cura L, Mestres CA. Similar survival after mitral valve replacement or repair for ischemic mitral regurgitation: a meta-analysis. Ann Thorac Surg. 2014;97:758-65. doi:10.1016/j.athoracsur.2013.10.044.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Goldstein D, Moskowitz AJ, Gelijns AC, et al. Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation. N Engl J Med. 2016;374:344-53. doi:10.1056/NEJMoa1512913.</mixed-citation><mixed-citation xml:lang="en">Goldstein D, Moskowitz AJ, Gelijns AC, et al. Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation. N Engl J Med. 2016;374:344-53. doi:10.1056/NEJMoa1512913.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Obadia JF, Messika-Zeitoun D, Leurent G, et al. MITRA-FR Investigators. Percutaneous repair or medical treatment for secondary mitral regurgitation. N Engl J Med. 2018;379:2297-306. doi:10.1056/NEJMoa1805374.</mixed-citation><mixed-citation xml:lang="en">Obadia JF, Messika-Zeitoun D, Leurent G, et al. MITRA-FR Investigators. Percutaneous repair or medical treatment for secondary mitral regurgitation. N Engl J Med. 2018;379:2297-306. doi:10.1056/NEJMoa1805374.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Stone GW, Lindenfeld J, Abraham WT, et al.; COAPT Investigators. Transcatheter mitral-valve repair in patients with heart failure. N Engl J Med. 2018;379:2307-18. doi:10.1056/NEJMoa1806640</mixed-citation><mixed-citation xml:lang="en">Stone GW, Lindenfeld J, Abraham WT, et al.; COAPT Investigators. Transcatheter mitral-valve repair in patients with heart failure. N Engl J Med. 2018;379:2307-18. doi:10.1056/NEJMoa1806640</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Baldetti L, Melillo F, Beneduce A, et al. Transcatheter Mitral Valve Implantation: Who are we Treating and What may we Expect? Am J Cardiol. 2019;123:1884-5. doi:10.1016/j.amjcard.2019.02.048.</mixed-citation><mixed-citation xml:lang="en">Baldetti L, Melillo F, Beneduce A, et al. Transcatheter Mitral Valve Implantation: Who are we Treating and What may we Expect? Am J Cardiol. 2019;123:1884-5. doi:10.1016/j.amjcard.2019.02.048.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Theriault-Lauzier P, Mylotte D, Dorfmeister M, et al. Quantitative multi-slice computed tomography assessment of the mitral valvular complex for transcatheter mitral valve interventions part 1: systematic measurement methodology and inter-observer variability. EuroIntervention. 2015;11:e1011-20. doi:10.4244/EIJY15M11_09.</mixed-citation><mixed-citation xml:lang="en">Theriault-Lauzier P, Mylotte D, Dorfmeister M, et al. Quantitative multi-slice computed tomography assessment of the mitral valvular complex for transcatheter mitral valve interventions part 1: systematic measurement methodology and inter-observer variability. EuroIntervention. 2015;11:e1011-20. doi:10.4244/EIJY15M11_09.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Bapat V. Valve-in-valve apps: why and how they were developed and how to use them. EuroIntervention. 2014;10 Suppl U:U44-51. doi:10.4244/EIJV10SUA7.</mixed-citation><mixed-citation xml:lang="en">Bapat V. Valve-in-valve apps: why and how they were developed and how to use them. EuroIntervention. 2014;10 Suppl U:U44-51. doi:10.4244/EIJV10SUA7.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Bapat V, Attia R, Thomas M. Effect of valve design on the stent internal diameter of a bioprosthetic valve: a concept of true internal diameter and its implications for the valve-invalve procedure. J Am Coll Cardiol Intv. 2014;7:115-27. doi:10.1016/j.jcin.2013.10.012.</mixed-citation><mixed-citation xml:lang="en">Bapat V, Attia R, Thomas M. Effect of valve design on the stent internal diameter of a bioprosthetic valve: a concept of true internal diameter and its implications for the valve-invalve procedure. J Am Coll Cardiol Intv. 2014;7:115-27. doi:10.1016/j.jcin.2013.10.012.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Urena M, Himbert D, Brochet E, et al. Transseptal Transcatheter Mitral Valve Replacement Using Balloon-Expandable Transcatheter Heart Valves A Step-by-Step Approach. J Am Coll Cardiol Intv. 2017;10:1905-19. doi:10.1016/j.jcin.2017.06.069.</mixed-citation><mixed-citation xml:lang="en">Urena M, Himbert D, Brochet E, et al. Transseptal Transcatheter Mitral Valve Replacement Using Balloon-Expandable Transcatheter Heart Valves A Step-by-Step Approach. J Am Coll Cardiol Intv. 2017;10:1905-19. doi:10.1016/j.jcin.2017.06.069.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Blanke P, Dvir D, Cheung A, et al. Mitral annular evaluation with CT in the context of transcatheter mitral valve replacement. J Am Coll Cardiol Img. 2015;8:612-5. doi:10.1016/j.jcmg.2014.07.028.</mixed-citation><mixed-citation xml:lang="en">Blanke P, Dvir D, Cheung A, et al. Mitral annular evaluation with CT in the context of transcatheter mitral valve replacement. J Am Coll Cardiol Img. 2015;8:612-5. doi:10.1016/j.jcmg.2014.07.028.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Bapat V, Pirone F, Kapetanakis S, et al. Factors influencing left ventricular outflow tract obstruction following a mitral valve- in-valve or valve-in-ring procedure, part 1. Catheter Cardiovasc Interv. 2015;86:747-60. doi:10.1002/ccd.25928.</mixed-citation><mixed-citation xml:lang="en">Bapat V, Pirone F, Kapetanakis S, et al. Factors influencing left ventricular outflow tract obstruction following a mitral valve- in-valve or valve-in-ring procedure, part 1. Catheter Cardiovasc Interv. 2015;86:747-60. doi:10.1002/ccd.25928.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Blanke P, Naoum C, Dvir D, et al. Predicting LVOT obstruction in transcatheter mitral valve implantation: concept of the neo-LVOT. J Am Coll Cardiol Img. 2017;10:482-5. doi:10.1016/j.jcmg.2016.01.005.</mixed-citation><mixed-citation xml:lang="en">Blanke P, Naoum C, Dvir D, et al. Predicting LVOT obstruction in transcatheter mitral valve implantation: concept of the neo-LVOT. J Am Coll Cardiol Img. 2017;10:482-5. doi:10.1016/j.jcmg.2016.01.005.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Wang DD, Eng M, Greenbaum A, et al. Predicting LVOT obstruction after TMVR. J Am Coll Cardiol Img. 2016;9:1349-52. doi:10.1016/j.jcmg.2016.01.017.</mixed-citation><mixed-citation xml:lang="en">Wang DD, Eng M, Greenbaum A, et al. Predicting LVOT obstruction after TMVR. J Am Coll Cardiol Img. 2016;9:1349-52. doi:10.1016/j.jcmg.2016.01.017.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Ren B, Rahhab Z, von der Thusen J, et al. Transcatheter Lotus valve implantation in a stenotic mitral valve. J Am Coll Cardiol Intv. 2016;9:e215-7.</mixed-citation><mixed-citation xml:lang="en">Ren B, Rahhab Z, von der Thusen J, et al. Transcatheter Lotus valve implantation in a stenotic mitral valve. J Am Coll Cardiol Intv. 2016;9:e215-7.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Vahanian A, Himbert D, Brochet E. Transseptal puncture. In: Di Mario C, Dangas GD, Barlis P, editors. Interventional Cardiology: Principles and Practice. London: Wiley-Blackwell 2011:383-93. doi:10.1002/9781118983652.ch62.</mixed-citation><mixed-citation xml:lang="en">Vahanian A, Himbert D, Brochet E. Transseptal puncture. In: Di Mario C, Dangas GD, Barlis P, editors. Interventional Cardiology: Principles and Practice. London: Wiley-Blackwell 2011:383-93. doi:10.1002/9781118983652.ch62.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Maisano F, La Canna G, Latib A, et al. Transseptal access for MitraClip procedures using surgical diathermy under echocardiographic guidance. EuroIntervention. 2012;8:579-86. doi:10.4244/EIJV8I5A89.</mixed-citation><mixed-citation xml:lang="en">Maisano F, La Canna G, Latib A, et al. Transseptal access for MitraClip procedures using surgical diathermy under echocardiographic guidance. EuroIntervention. 2012;8:579-86. doi:10.4244/EIJV8I5A89.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Fassa AA, Himbert D, Vahanian A. Mechanisms and management of TAVR-related complications. Nat Rev Cardiol. 2013;10:685-95. doi:10.1038/nrcardio.2013.156.</mixed-citation><mixed-citation xml:lang="en">Fassa AA, Himbert D, Vahanian A. Mechanisms and management of TAVR-related complications. Nat Rev Cardiol. 2013;10:685-95. doi:10.1038/nrcardio.2013.156.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Fassa AA, Himbert D, Brochet E, et al. Emergency transseptal transcatheter mitral valveinvalve implantation. EuroIntervention. 2013;9:636-42. doi:10.4244/EIJV9I5A101.</mixed-citation><mixed-citation xml:lang="en">Fassa AA, Himbert D, Brochet E, et al. Emergency transseptal transcatheter mitral valveinvalve implantation. EuroIntervention. 2013;9:636-42. doi:10.4244/EIJV9I5A101.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Guerrero M, Wang DD, O’Neill W. Percutaneous rescue of an embolized valve after transcatheter mitral valve replacement. J Am Coll Cardiol Intv. 2017;10:627-9. doi:10.1016/j.jcin.2017.01.020.</mixed-citation><mixed-citation xml:lang="en">Guerrero M, Wang DD, O’Neill W. Percutaneous rescue of an embolized valve after transcatheter mitral valve replacement. J Am Coll Cardiol Intv. 2017;10:627-9. doi:10.1016/j.jcin.2017.01.020.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Naksuk N, Asirvatham SJ. Iatrogenic atrial septal defect: reassurance or inquisitiveness. J Interv Card Electrophysiol. 2018;52(2):137-40. doi:10.1007/s10840-018-0369-4.</mixed-citation><mixed-citation xml:lang="en">Naksuk N, Asirvatham SJ. Iatrogenic atrial septal defect: reassurance or inquisitiveness. J Interv Card Electrophysiol. 2018;52(2):137-40. doi:10.1007/s10840-018-0369-4.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Stone GW, Vahanian AS, Adams DH, et al. Clinical trial design principles and endpoint definitions for transcatheter mitral valve repair and replacement: part 1: clinical trial design principles: a consensus document from the Mitral Valve Academic Research Consortium. J Am Coll Cardiol. 2015;66:278-307. doi:10.1016/j.jacc.2015.05.046.</mixed-citation><mixed-citation xml:lang="en">Stone GW, Vahanian AS, Adams DH, et al. Clinical trial design principles and endpoint definitions for transcatheter mitral valve repair and replacement: part 1: clinical trial design principles: a consensus document from the Mitral Valve Academic Research Consortium. J Am Coll Cardiol. 2015;66:278-307. doi:10.1016/j.jacc.2015.05.046.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Wang DD, Guerrero M, Eng MH, et al. Alcohol Septal Ablation to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Replacement. J Am Coll Cardiol Intv. 2019;12:1268-79. doi:10.1016/j.jcin.2019.02.034.</mixed-citation><mixed-citation xml:lang="en">Wang DD, Guerrero M, Eng MH, et al. Alcohol Septal Ablation to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Replacement. J Am Coll Cardiol Intv. 2019;12:1268-79. doi:10.1016/j.jcin.2019.02.034.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Khan JM, Bch BM, Babaliaros VC, et al. Anterior Leaflet Laceration to Prevent Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Replacement. J Am Coll Cardiol. 2019;73:2521-34. doi:10.1016/j.jacc.2019.02.076.</mixed-citation><mixed-citation xml:lang="en">Khan JM, Bch BM, Babaliaros VC, et al. Anterior Leaflet Laceration to Prevent Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Replacement. J Am Coll Cardiol. 2019;73:2521-34. doi:10.1016/j.jacc.2019.02.076.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Guerrero M, Wang DD, Himbert D, et al. Short-term results of alcohol septal ablation as a bail-out strategy to treat severe left ventricular outflow tract obstruction after transcatheter mitral valve replacement in patients with severe mitral annular calcification. Catheter Cardiovasc Interv. Off J Soc Card Angiogr Interv. 2017;90(7):1220-6. doi:10.1002/ccd.26975.</mixed-citation><mixed-citation xml:lang="en">Guerrero M, Wang DD, Himbert D, et al. Short-term results of alcohol septal ablation as a bail-out strategy to treat severe left ventricular outflow tract obstruction after transcatheter mitral valve replacement in patients with severe mitral annular calcification. Catheter Cardiovasc Interv. Off J Soc Card Angiogr Interv. 2017;90(7):1220-6. doi:10.1002/ccd.26975.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Taramasso M, Nietlispach F, Schmid M, Maisano F. Corevalve Evolut R implantation to treat severe left ventricle outflow tract obstruction following mitral valve-in-ring: first-inman report. Eur Heart J. 2016;37:317. doi:10.1093/eurheartj/ehv617.</mixed-citation><mixed-citation xml:lang="en">Taramasso M, Nietlispach F, Schmid M, Maisano F. Corevalve Evolut R implantation to treat severe left ventricle outflow tract obstruction following mitral valve-in-ring: first-inman report. Eur Heart J. 2016;37:317. doi:10.1093/eurheartj/ehv617.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Nguyen A, Urena M, Himbert D, et al. Late displacement after transcatheter mitral valve replacement for degenerative mitral valve disease with massive annular calcification. J Am Coll Cardiol Intv. 2016;9:1633-4. doi:10.1016/j.jcin.2016.05.033.</mixed-citation><mixed-citation xml:lang="en">Nguyen A, Urena M, Himbert D, et al. Late displacement after transcatheter mitral valve replacement for degenerative mitral valve disease with massive annular calcification. J Am Coll Cardiol Intv. 2016;9:1633-4. doi:10.1016/j.jcin.2016.05.033.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Bapat VV, Khaliel F, Ihleberg L. Delayed migration of Sapien valve following a transcatheter mitral valve-in-valve implantation. Catheter Cardiovasc Interv. 2014;83:E150-4. doi:10.1002/ccd.25076.</mixed-citation><mixed-citation xml:lang="en">Bapat VV, Khaliel F, Ihleberg L. Delayed migration of Sapien valve following a transcatheter mitral valve-in-valve implantation. Catheter Cardiovasc Interv. 2014;83:E150-4. doi:10.1002/ccd.25076.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Capretti G, Urena M, Himbert D, et al. Valve thrombosis after transcatheter mitral valve replacement. J Am Coll Cardiol. 2016;68:1814-5. doi:10.1016/j.jacc.2016.07.757.</mixed-citation><mixed-citation xml:lang="en">Capretti G, Urena M, Himbert D, et al. Valve thrombosis after transcatheter mitral valve replacement. J Am Coll Cardiol. 2016;68:1814-5. doi:10.1016/j.jacc.2016.07.757.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
