russjcardiolРоссийский кардиологический журналRussian Journal of Cardiology1560-40712618-7620«SILICEA-POLIGRAF» LLC10.15829/1560-4071-2019-12-153-161russjcardiol-3614Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWКальциевый индекс как скрининговый метод диагностики сердечно-сосудистых заболеванийCalcium score as a screening method for cardiovascular disease diagnosishttps://orcid.org/0000-0003-1733-267XЖуравлевК. Н.ZhuravlevK. N.

Кирилл Николаевич Журавлев— врач-рентгенолог, зав. отделением лучевой диагностики

Москва

kir232@mail.ruhttps://orcid.org/0000-0002-6310-7636ВасильеваЕ. Ю.VasilievaE. Yu.

Елена Юрьевна Васильева — д. м.н., профессор, руководитель лаборатории атеротромбоза, кафедра кардиологии

Москва

moscowcardio_23@yahoo.comhttps://orcid.org/0000-0002-5649-2193СиницынВ. Е.SinitsynV. E.

Валентин Евгеньевич Синицын — д. м.н., профессор, зав. кафедрой лучевой диагностики, факультет фундаментальной медицины

Москва

vsini@mail.ruhttps://orcid.org/0000-0001-6190-6808ШпекторА. В.SpectorA. V.

Александр Вадимович Шпектор — д.м.н., профессор, зав. кафедрой неотложной кардиологии

Москва

moscowcardio_23@yahoo.comГБУЗ Городская клиническая больница им. И. В. Давыдовского Департамента здравоохранения города МосквыРоссияI. V. Davydovsky City Clinical HospitalRussian FederationФГБОУ ВО Московский государственный медико-стоматологический университет им. А. И. ЕвдокимоваRussian FederationMoscow State University of Medicine and DentistryRussian FederationФГБОУ ВО Московский государственный университет им. М. В. ЛомоносоваRussian FederationMoscow State UniversityRussian Federation201913112019012153161Copyright © Журавлев К.Н., Васильева Е.Ю., Синицын В.Е., Шпектор А.В., 20192019Журавлев К.Н., Васильева Е.Ю., Синицын В.Е., Шпектор А.В.Zhuravlev K.N., Vasilieva E.Y., Sinitsyn V.E., Spector A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://russjcardiol.elpub.ru/jour/article/view/3614

Кальциноз коронарных артерий является характерным признаком коронарного атеросклероза, который часто выявляется при компьютерной томографии (КТ) органов грудной клетки. Стандартизованным методом оценки коронарного кальциноза является кальциевый индекс по методу Агатстона. Полуколичественная оценка коронарного кальция с электрокардиографической (ЭКГ) синхронизацией считается сильным прогностическим фактором возникновения коронарных событий у асимптомных пациентов. Нулевой кальциевый индекс может служить как наиболее сильный негативный фактор риска развития сердечно-сосудистых событий в течение 10-15 лет. Согласно международным рекомендациям кальциевы индекс следует использовать у пациентов промежуточного риска и низкого риска с сердечно-сосудистым семейным анамнезом, а также у диабетиков старше 40 лет. Целью данного обзора является обобщение современных данных о клиническом значении кальциевого индекса с учетом результатов международных многоцентровых исследований, современных международных рекомендаций и дальнейших перспектив по более широкому применению исследования в кардиологической практике.

Coronary artery calcification (CAC) is characteristic of coronary atherosclerosis, which is often detected by chest computed tomography. The standardized method for assessing CAC is the calcium score (CS) using the Agatston scoring system. A semi-quantitative ECG-synchronized assessment of coronary calcium score is considered a strong prognostic factor for coronary events in asymptomatic patients. Zero CS can serve as the strongest unfavorable risk factor for cardiovascular events in 10-15 years. According to international guidelines, CS should be used in patients of intermediate and low risks with a family history of cardiovascular diseases, as well as in patients with diabetes older than 40 years. The aim of this review was to summarize current data on the clinical significance of CS taking into account the results of international multicenter studies, current international guidelines and further prospects for its wider use in cardiology practice. 

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The authors declare that there are no conflicts of interest present.