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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2019-12-10-14</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-3595</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Магнитно-резонансная томография с парамагнитным контрастным усилением в оценке атеросклеротического поражения аорты и его взаимосвязи с тяжестью повреждения миокарда при инфаркте</article-title><trans-title-group xml:lang="en"><trans-title>Contrast enhanced magnetic resonance imaging in assessment of aortic atherosclerosis and its relation to severity of myocardial injury due to infarction</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4871-3283</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимова</surname><given-names>А С</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>К.м.н., научный сотрудник отделения рентгеновских и томографических методов диагностики НИИ кардиологии Томского НИМЦ</p><p>Томск</p></bio><bio xml:lang="en"/><email xlink:type="simple">asmaximova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5649-2193</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В Е</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsyn</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Д.м.н., профессор, зав. кафедрой лучевой диагностики и лучевой терапии Факультета фундаментальной медицины,</p><p>Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">vsini@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7324-504X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лишманов</surname><given-names>Ю Б</given-names></name><name name-style="western" xml:lang="en"><surname>Lishmanov</surname><given-names>Yu. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Д.м.н., профессор, Член-корреспондент РАН, Руководитель научного направления «Лучевая диагностика» НИИ кардиологии Томского НИМЦ</p><p>Томск</p></bio><bio xml:lang="en"/><email xlink:type="simple">zamdir@cardio-tomsk.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7352-6068</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Усов</surname><given-names>В Ю</given-names></name><name name-style="western" xml:lang="en"><surname>Ussov</surname><given-names>W. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Д. м.н., профессор, зав. отделением рентгеновских и томографических методов диагностики НИИ кардиологии Томского НИМЦ</p><p>Томск</p></bio><bio xml:lang="en"/><email xlink:type="simple">ussov1962@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Научно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наук<country>Россия</country></aff><aff xml:lang="en">Cardiology Research Institute, Tomsk National Research Medical Center<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Московский государственный университет им. М.В.Ломоносова<country>Россия</country></aff><aff xml:lang="en">Moscow State University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Научно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наук<country>Россия</country></aff><aff xml:lang="en">Cardiology Research Institute, Tomsk National Research Medical Center; &#13;
Tomsk Polytechnic University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">Научно-исследовательский институт кардиологии, Томский национальный исследовательский медицинский центр Российской академии наук; Национальный исследовательский Томский политехнический университет<country>Россия</country></aff><aff xml:lang="en">Cardiology Research Institute, Tomsk National Research Medical Center; &#13;
Tomsk Polytechnic University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>05</day><month>11</month><year>2019</year></pub-date><volume>0</volume><issue>12</issue><fpage>10</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Максимова А.С., Синицын В.Е., Лишманов Ю.Б., Усов В.Ю., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Максимова А.С., Синицын В.Е., Лишманов Ю.Б., Усов В.Ю.</copyright-holder><copyright-holder xml:lang="en">Maksimova A.S., Sinitsyn V.E., Lishmanov Y.B., Ussov W.Y.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/3595">https://russjcardiol.elpub.ru/jour/article/view/3595</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. По данным магнитно-резонансной томографии (МРТ) с парамагнитным контрастным усилением (ПМКУ) изучить взаимоотношения повреждения миокарда и контрастирования атеросклеротического поражения аорты у пациентов, перенесших острый инфаркт миокарда и проходивших МРТ сердца перед операцией аорто-коронарного шунтирования и пластикой по Дору или Мениканти.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование были включены 42 пациента (38 мужчин, 4 женщины) проходивших МРТ сердца с ПМКУ. Средний возраст составил 57,7±8,75 лет. Для анализа атеросклеротического поражения аорты оценивались Т1-взв. сканы в аксиальной плоскости до и спустя 10-15 мин после ПМКУ. Наряду с визуальным анализом картины определялись диаметр, толщина стенки аорты, и индекс усиления (ИУ) Т1-взв. спин-эхо изображения (TR=400-650 мс, TE=12-20 мс), как отношение интенсивностей области стенки аорты при ПМКУ и исходном изображении: ИУ = Инт.T1-ВИ(контраст)/Инт.T1-ВИ(исходное). У всех пациентов по данным МРТ сердца с ПМКУ оценивалась доля повреждения миокарда левого желудочка, как соотношение массы миокарда, поврежденного при перенесенном инфаркте, и массы левого желудочка: ДПМиоклж = ММОИМ/Млж.</p></sec><sec><title>Результаты</title><p>Результаты. В зависимости от значения ИУ аорты пациенты были разделены на три группы: 1 гр. (n=9) с ИУ≤1,05; 2 гр. (n=15) с 1,05&lt;ИУ≤1,15; 3 гр. (n=18) с ИУ&gt;1,15. Мы сравнили значения толщины стенки и диаметра нисходящей аорты среди этих групп. Провели попарный анализ с введением поправки Бонферрони для выявления межгрупповых различий. Не выявлено значимых различий по диаметру аорты этих групп (F=0,15; p=0,86); значения составили 2,41±0,33; 2,54±0,63; 2,53±0,51 см, соответственно. Толщина стенки аорты в группах 1-3 составила 2,05±0,58 мм, 3,34±0,68 мм и 3,80±0,46 мм (F=17,39; p&lt;0,001). Различаются первая и вторая, первая и третья группы, а между второй и третьей статистически значимых различий не выявлено. Между группами 1, 2 и 3 отмечены также рост и различия по показателю  ДПМиоклж, который составил при минимальном ИУ аорты (группа 1) 0,11±0,03, при промежуточном ИУ (группа 2) – 0,19±0,08, а при высоком ИУ – 0,25±0,15.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study the contrast enhanced magnetic resonance imaging (CE-MRI) role in assessment of aortic atherosclerosis and its relation to severity of myocardial injury in myocardial infarction (MI) patients which underwent cardiac MRI before coronary artery bypass grafting and Dor or Menicanti procedures.</p></sec><sec><title>Material and methods</title><p>Material and methods. The study included 42 patients (38 men, 4 women) who underwent CE-MRI (mean age 57,7±8,75 years). In order to analyze the aortic atherosclerosis, axial T1 weighted images before and after 10-15 minutes after CE was evaluated. Along with visual analysis, the diameter, thickness of the aortic wall, and index of enhancement (IE) of T1 weighted image (WI) (TR=400-650 ms, TE=12-20 ms), as the ratio of postand precontrast intensities of the aortic wall: IE=(Intensity T1-WI post-contrast)/ (Intensity T1-WI pre-contrast) were determined. According to the cardiac CEMRI, the proportion of left ventricle (LV) injury as the ratio of the MI injury and theLV mass was estimated.</p></sec><sec><title>Results</title><p>Results. Depending on aortic IE value, patients were divided into three groups: group 1 (9 people) with IE ≤1,05; group 2 (15 people) with 1,05&lt; IE ≤1,15; group 3 (18 people) with IE &gt;1,15. We compared the descending aortic wall thickness and the diameter among these groups. To identify intergroup differences one-way ANOVA with Bonferroni correction was carried out. There were no significant differences in the descending aortic diameters (F=0,15; p=0,86): group 1 — 2,41±0,33, group 2 — 2,54±0,63, group 3 — 2,53±0,51 cm. The thickness of the aortic wall in groups was 2,05±0,58 mm, 3,34±0,68 mm and 3,80±0,46 mm (F=17,39; p&lt; 0,001), respectively. The first and second, first and third groups were distinguished, and there was no significant difference between the second and third groups. Between groups 1, 2 and 3 were also noted the increase and differences in proportion of LV injury, which amounted to 0,11±0,03 with a minimum IE (group 1), with an intermediate IE (group 2) — 0,19±0,08, and with high IE — 0,25±0,15.</p></sec><sec><title>Conclusion</title><p>Conclusion. CE-MRI of the aortic wall can be used as a method of visualizing atherosclerosis and predicting the complications of aortic atherosclerosis. Moreover, the assessment of aortic atherosclerosis can be used in combination with conventional heart examination. The increased CE into the aortic wall in patients with advanced atherosclerosis is usually associated with a greater severity of myocardial injury. During cardiac CE-MRI it is advisable to assess the descending aorta state by calculation of IE T1-WI MRI to clarify the atherosclerosis severity and cardiovascular risk.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>магнитно-резонансная томография</kwd><kwd>парамагнитное контрастирование</kwd><kwd>атеросклероз аорты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>magnetic resonance imaging</kwd><kwd>paramagnetic enhancement</kwd><kwd>aortic atherosclerosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lozano R, Naghavi M, Foreman K. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. 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