russjcardiolРоссийский кардиологический журналRussian Journal of Cardiology1560-40712618-7620«SILICEA-POLIGRAF» LLC10.15829/1560-4071-2019-4-48-52russjcardiol-3150Research ArticleВ ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУSUPPORTING A PRACTITIONERОжирение и беременность: сердечно-сосудистые и метаболические рискиObesity and pregnancy: cardiovascular and metabolic riskshttps://orcid.org/0000-0001-8654-7020ВеселовскаяН. Г.VeselovskayaN. G.

Веселовская Надежда Григорьевна — доктор медицинских наук, ассистент кафедры терапии и общей врачебной практики с курсом ДПО; старший научный сотрудник отдела мультифокального атеросклероза; зав. кардиологическим отделением № 4 Алтайского краевого кардиологического диспансера

Барнаул, Кемерово

nadezhda100@rambler.ruhttps://orcid.org/0000-0002-2810-6531ЧумаковаГ. А.ChumakovaG. A.

Чумакова Галина Александровна — доктор медицинских наук, профессор кафедры терапии и общей врачебной практики с курсом ДПО; ведуший научный сотрудник отдела мультифокального атеросклероза

Барнаул, Кемерово

g.a.chumakova@mail.ruФГБОУ ВО Алтайский государственный медицинский университет Минздрава России; ФГБУ НИИ Комплексных проблем сердечно-сосудистых заболеваний СО РАМН; КГБУЗ Алтайский краевой кардиологический диспансерРоссияAltai State Medical University; Research Institute for Complex Issues of Cardiovascular Diseases; Altai Regional Cardiologic DispensaryRussian Federation201902022019044852Copyright © Веселовская Н.Г., Чумакова Г.А., 20192019Веселовская Н.Г., Чумакова Г.А.Veselovskaya N.G., Chumakova G.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://russjcardiol.elpub.ru/jour/article/view/3150

Последние годы ожирение стало лидировать как фактор сердечно-сосудистого риска в разных клинических группах, включая женщин детородного возраста. По данным эпидемиологических исследований за последние 10 лет ожирение у беременных женщин регистрируется в 15-38% случаев. Ожирение является доказанным фактором риска, осложняющим течение беременности, родов и послеродового периода. Наличие ожирения у женщины до родов является фактором риска бесплодия, выкидышей в раннем сроке и врожденных аномалий развития плода. Избыточный вес и ожирение у беременных приводят к увеличению материнской и перинатальной заболеваемости и смертности. Несмотря на высокую распространенность ожирения у беременных механизмы возникновения осложнений, методы коррекции и профилактики изучены недостаточно. Учитывая неблагоприятный прогноз у детей матерей с ожирением, необходимы исследования по оценке роли висцеральной жировой ткани, адипокинов в формировании инсулинорезистентности, эндотелиальной дисфункции, системного воспаления в риске развития осложнений у беременной женщины и рожденного ребенка, а также программы первичной профилактики ожирения в детородном возрасте и прегравидарной подготовки.

In recent years, obesity has become the leader as a cardiovascular risk factor in various clinical groups, including women of childbearing age. According to epidemiological studies over the past 10 years, obesity in pregnant women is recorded in 15-38% of cases. Obesity is a proven risk factor that complicates pregnancy, childbirth and the postpartum period. The presence of obesity in women before childbirth is a risk factor for infertility, miscarriage in the early period and congenital malformations in the fetus. Overweight and obesity in pregnant women lead to an increase in maternal and perinatal morbidity and mortality. Despite the high prevalence of obesity in pregnant women, the mechanisms for the occurrence of complications, methods of correction and prevention have not been studied enough. Considering the unfavorable prognosis in children of obese mothers, studies are needed to assess the role of internal adipose tissue, adipokines in the formation of insulin resistance, endothelial dysfunction. It is also needed to evaluate effect of systemic inflammation in the risk of developing complications in a pregnant woman and child, as well as programs for primary prevention of obesity in childbearing age.

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The authors declare that there are no conflicts of interest present.