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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2019-6-34-41</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-3090</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Риск возникновения инфаркта миокарда и социальная поддержка среди населения 25-64 лет в России/Сибири</article-title><trans-title-group xml:lang="en"><trans-title>The risk of myocardial infarction, and social support among the population of 25-64 years in Russia/Siberia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5701-7856</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гафаров Валерий Васильевич — доктор медицинских наук, профессор, руководитель Межведомственной лаборатории эпидемиологии сердечно-сосудистых заболеваний, лаборатории психологических и социологических проблем терапевтических заболеваний.</p><p>Новосибирск.</p></bio><bio xml:lang="en"><p>Novosibirsk.</p></bio><email xlink:type="simple">valery.gafarov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8313-3893</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Громова Елена Алексеевна — доктор медицинских наук, ведущий научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний, Межведомственной лаборатории эпидемиологии сердечно-сосудистых заболеваний.</p><p>Новосибирск.</p></bio><bio xml:lang="en"><p>Novosibirsk.</p></bio><email xlink:type="simple">elena.a.gromova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5255-5647</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagulin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гагулин Игорь Вячеславович — старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний, Межведомственной лаборатории эпидемиологии сердечно-сосудистых заболеваний.</p><p>Новосибирск.</p></bio><bio xml:lang="en"><p>Novosibirsk.</p></bio><email xlink:type="simple">gagulin@ngs.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8101-6121</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панов</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Panov</surname><given-names>D. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Панов Дмитрий Олегович — кандидат медицинских наук, старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний, Межведомственной лаборатории эпидемиологии сердечно-сосудистых заболеваний.</p><p>Новосибирск.</p></bio><bio xml:lang="en"><p>Novosibirsk.</p></bio><email xlink:type="simple">dimitriy2004@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5979-5045</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крымов</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krymov</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Крымов Эльдар Абаевич — аспирант лаборатории психологических и социологических проблем терапевтических заболеваний, Межведомственной лаборатории эпидемиологии сердечно-сосудистых заболеваний.</p><p>Новосибирск.</p></bio><bio xml:lang="en"><p>Novosibirsk.</p></bio><email xlink:type="simple">darinich_83@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7860-6537</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сулейманов</surname><given-names>Р. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Suleymanov</surname><given-names>R. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сулейманов Рафаэль Ринатович — аспирант Межведомственной лаборатории эпидемиологии сердечно-сосудистых заболеваний.</p><p>Новосибирск.</p></bio><bio xml:lang="en"><p>Novosibirsk.</p></bio><email xlink:type="simple">suleymanov@cardioc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5380-9434</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гафарова Альмира Валерьевна — кандидат медицинских наук, старший научный сотрудник лаборатории психологических и социологических проблем терапевтических заболеваний, Межведомственной лаборатории эпидемиологии сердечно-сосудистых заболеваний.</p><p>Новосибирск.</p></bio><bio xml:lang="en"><p>Novosibirsk.</p></bio><email xlink:type="simple">alma77@ngs.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт терапии и профилактической медицины — филиал ФГБНУ ФИЦ Института цитологии и Генетики СО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Therapy and Preventive Medicine — Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>04</day><month>03</month><year>2019</year></pub-date><volume>0</volume><issue>6</issue><fpage>34</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гафаров В.В., Громова Е.А., Гагулин И.В., Панов Д.О., Крымов Э.А., Сулейманов Р.Р., Гафарова А.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Гафаров В.В., Громова Е.А., Гагулин И.В., Панов Д.О., Крымов Э.А., Сулейманов Р.Р., Гафарова А.В.</copyright-holder><copyright-holder xml:lang="en">Gafarov V.V., Gromova E.A., Gagulin I.V., Panov D.O., Krymov E.A., Suleymanov R.R., Gafarova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/3090">https://russjcardiol.elpub.ru/jour/article/view/3090</self-uri><abstract><sec><title>Цель</title><p>Цель. Определить влияние социальной поддержки на риск возникновения инфаркта миокарда (ИМ) в открытой популяции населения 25-64 лет в России/Сибири.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В рамках III скрининга программы ВОЗ “MONICA-psychosocial” обследована случайная репрезентативная выборка населения обоего пола 25-64 лет Новосибирска в 1994г (мужчины: n=657 44,3±0,4 года, отклик — 82,1%; женщины: n=689, 45,4±0,4 года, отклик — 72,5%). Программа скринирующего обследования включала: регистрацию социально-демографических данных, определение социальной поддержки (ICC — индекс близких контактов, SNI — индекс социальных связей). Срок проспективного наблюдения за участниками составил 16 лет. В исследовании выделены конечные точки — впервые возникшие случаи ИМ.</p></sec><sec><title>Результаты</title><p>Результаты. В открытой популяции населения 25-64 лет низкий ICC был у 62% мужчин и 56,8% женщин (х2=22,603 df=2 P=0,0001). При распределении по возрастным группам наиболее низкий ICC наблюдался у мужчин в возрастной группе 55-64 лет — 64,6% (х2=14,85 df=2 P=0,0001) и у женщин в возрасте 35-44 лет — 60,6% (х2=3,917 df=2 P=0,141). Низкий SNI в открытой популяции 25-64 лет был у 43,5% мужчин и 33,9% женщин (х2=21,546 df =2 P=0,0001). Наиболее низкий SNI среди мужчин был среди лиц молодой возрастной группы 25-34 лет — 50% (х2=15,894 df=3 P=0,001), у женщин — в группе 35-44 лет (39,4%) (х2=1,071 df=3 P=1). За 16-летний период наблюдения однофакторный регрессионный анализ Кокса показал увеличение риска развития ИМ среди лиц с низким показателем индекса ICC у мужчин в 5,2 (95% доверительный интервал (ДИ) 1,947-19,383; p&lt;0,05) раз и женщин в 4,9 раз (95% ДИ 1,108-21,762; p&lt;0,05). Риск развития инфаркта миокарда за 16-летний период наблюдения в однофакторной регрессионной модели Кокса был выше у лиц с низким показателем индекса SNI, как среди мужчин ОР=3,1 (95% ДИ 1,138-9,247; p&lt;0,05), так и среди женщин ОР=2,9 (95% ДИ 1,040-8,208; p&lt;0,05). С помощью многофакторного моделирования установлено увеличение риска возникновения ИМ у лиц с низким уровнем социальной поддержки: среди мужчин с неблагополучным семейным положением, занимающихся физическим трудом, а среди женщин — с низким уровнем образования. Заключение. Социальная поддержка является протективным фактором риска развития ИМ, как у мужчин, так и у женщин.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To determine the impact of social support on the risk of myocardial infarction (MI) in an open population of 25-64 years in Russia/Siberia.</p></sec><sec><title>Material and methods</title><p>Material and methods. As part of the III screening of the WHO MONICA-psychosocial program, a random representative sample of Novosibirsk population of both sexes aged 25-64 was examined (men: n=657, 44,3±0,4 years, response — 82,1%; women: n=689, 45,4±0,4 years, response — 72,5%). The screening survey program included: registration of socio-demographic data, definition of social support (ICC — indices of close contacts, SNI — social network index). The duration of the prospective observation of the participants was 16 years. First occurrences of MI were an endpoints of study.</p></sec><sec><title>Results</title><p>Results. We revealed that 62% of men and 56,8% of women had a low ICC (х2=22,603 df=2 P=0,0001). When distributed by age groups, the lowest ICC was observed in men in the 55-64 age group — 64,6% (х2=14,85 df=2 P=0,0001) and in 35-44 women — 60,6% (х2=3,917 df=2 P=0,141). Low SNI was among 43,5% of males and 33,9% of females (х2=21,546 df=2 P=0,0001). The lowest SNI among men was among the young age group of 25-34 years old — 50% (х2=15,894 df=3 P=0,001), for women — in the group of 35-44 years (39,4%) (х2=0,071 df=3 P=1). Over the 16-year observation period, Cox’s regression analysis showed an increase in the MI risk among persons with a low ICC index in men 5,2 (95% confidence interval (CI) 1,947-19,383; p&lt;0,05) and women 4,9 times (95% CI 0,108-20,762; p&lt;0,05). The risk of MI over a 16-year observation period in the single-factor Cox regression model was higher in individuals with a low SNI index, as among men OR=3,1 (95% CI 1,138-9,247; p&lt;0,05) and among women, RR=2,9 (95% CI 1,040¬8,208; p&lt;0,05). With the use of multivariate modeling, an increased risk of MI is found in people with low social support: among men with unfavorable family situation engaged in physical labor, and among women with a low level of education. Conclusion. Social support is a protective risk factor for MI in both men and women.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>социальная поддержка</kwd><kwd>инфаркт миокарда</kwd><kwd>популяция</kwd><kwd>риск</kwd><kwd>мужчины</kwd><kwd>женщины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>social support</kwd><kwd>myocardial infarction</kwd><kwd>population</kwd><kwd>risk</kwd><kwd>men</kwd><kwd>women</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tanaka A, Shipley MJ, Welch CA, et al. Socioeconomic inequality in recovery from poor physical and mental health in mid-life and early old age: prospective Whitehall II cohort study. J Epidemiol Community Health. 2018;72 (4):309-13. doi:10.1136/jech-2017-209584.</mixed-citation><mixed-citation xml:lang="en">Tanaka A, Shipley MJ, Welch CA, et al. 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