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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2018-10-127-135</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-3081</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИКА И ФАРМАКОТЕРАПИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GUIDELINES FOR THE PRACTITIONER</subject></subj-group></article-categories><title-group><article-title>Двойная антитромбоцитарная терапия у пациентов с острым коронарным синдромом. Результаты реальной клинической практики</article-title><trans-title-group xml:lang="en"><trans-title>Dual antiplatelet therapy in patients with acute coronary syndrome. Results of actual clinical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4642-3610</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, член-корреспондент РАН, директор; заведующий кафедрой кардиологии и сердечно-сосудистой хирургии.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3729-616X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кашталап</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kashtalap</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, заведующий лабораторией патофизиологии мультифокального атеросклероза; доцент кафедры кардиологии и сердечно-сосудистой хирургии.</p></bio><email xlink:type="simple">v_kash@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НИИ комплексных проблем сердечно-сосудистых заболеваний; Кемеровский государственный медицинский университет Минздрава России<country>Россия</country></aff><aff xml:lang="en">Research Institute for Complex Issues of Cardiovascular Diseases; Kemerovo State Medical Academy of the Ministry of Health<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>24</day><month>11</month><year>2018</year></pub-date><volume>0</volume><issue>10</issue><fpage>127</fpage><lpage>135</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Барбараш О.Л., Кашталап В.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Барбараш О.Л., Кашталап В.В.</copyright-holder><copyright-holder xml:lang="en">Barbarash O.L., Kashtalap V.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/3081">https://russjcardiol.elpub.ru/jour/article/view/3081</self-uri><abstract><p>В обзорной статье представлено современное состояние вопроса использования двойной антитромбоцитарной терапии (ДАТТ) у пациентов с острым коронарным синдромом (ОКС) на основании современных клинических рекомендаций и в реальной клинической практике. Обсуждаются основные отличия в частоте использования и длительности ДАТТ в различных странах; приводится анализ характеристик пациентов, включенных в рандомизированные клинические исследования и популяции пациентов реальной клинической практики, принимающих ДАТТ после перенесенного ОКС. Использованы литературные источники из открытых баз данных PubMed, MEDLINE, eLibrary.</p></abstract><trans-abstract xml:lang="en"><p>The review article presents the state-of-the-art of use of dual antiplatelet therapy (DAPT) in patients with acute coronary syndrome (ACS) based on modern clinical guidelines and in actual clinical practice. The main differences in the frequency of use and duration of DAPT in different countries are discussed. The study included analysis of the characteristics of patients in randomized clinical trials and patients in actual clinical practice who take DATT after undergoing ACS. Literature sources from open databases PubMed, MEDLINE, eLibrary are used.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>двойная антитромбоцитарная терапия</kwd><kwd>острый коронарный синдром</kwd><kwd>приверженность к терапии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>dual antiplatelet therapy</kwd><kwd>acute coronary syndrome</kwd><kwd>compliance</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Барбараш О.Л., Каретникова В. Н., Кашталап В. В. Пациент после инфаркта миокарда: как снизить риск повторного ишемического события? Кардиосоматика. 2015; 6(2):12-9.</mixed-citation><mixed-citation xml:lang="en">Barbarash OL, Karetnikova VN, Kashtalap VV. The patient after myocardial infarction: how to reduce a risk of recurrent ischemic event? Cardiosomatics. 2015; 6(2):12-9. 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