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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2018-4-89-92</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-2717</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МНЕНИЕ ПО ПРОБЛЕМЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OPINION ON THE ISSUE</subject></subj-group></article-categories><title-group><article-title>СНИЖЕНИЕ СЕРДЕЧНО-СОСУДИСТОГО РИСКА ПРИ САХАРНОМ ДИАбЕТЕ 2 ТИПА НА ФОНЕ ЛЕЧЕНИЯ  ЛИРАГЛУТИДОМ И ЕГО ПЛЕЙОТРОПНЫЙ ЭФФЕКТ — МАНДАТ ДЛЯ КАРДИОЛОГА И ТЕРАПЕВТА</article-title><trans-title-group xml:lang="en"><trans-title>LIRAGLUTIDE PLEIOTROPIC EFFECT IN CARDIOVASCULAR RISK REDUCTION IN TYPE 2 DIAbETES —   A MANDATE FOR CARDIOLOGIST AND INTERNIST</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5981-1754</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Недогода</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nedogoda</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., профессор, зав. кафедрой терапии и эндокринологии факультета усовершенствования врачей ФУВ.</p><p>SPIN-код: 7005-7846</p></bio><bio xml:lang="en"><p>Volgograd.</p></bio><email xlink:type="simple">nedogodasv@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Волгоградский государственный медицинский университет Минздрава России.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Volgograd State Medical University of the Ministry of Health.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>09</day><month>05</month><year>2018</year></pub-date><volume>0</volume><issue>4</issue><fpage>89</fpage><lpage>92</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Недогода С.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Недогода С.В.</copyright-holder><copyright-holder xml:lang="en">Nedogoda S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/2717">https://russjcardiol.elpub.ru/jour/article/view/2717</self-uri><abstract><p>Результаты целого ряда крупных исследований (LEADER, EMPA-REG, CANVAS) убедительно доказывают целесообразность применения современных сахароснижающих препаратов для успешного управления кардиоваскулярным риском у пациентов с сахарным диабетом (СД) 2 типа. В данной работе всесторонне рассмотрены и проанализированы возможные механизмы и преимущества снижения сердечно-сосудистого риска у пациентов с СД 2 типа при назначении агониста глюкагон-подобного пептида 1 лираглутида (Виктоза®).</p></abstract><trans-abstract xml:lang="en"><p>The data from a range of large trials (LEADER, EMPA-REG, CANVAS) show evidently the practical use of the modern glucose lowering drugs usage for successful management of cardiovascular risk in type 2 diabetes (DM2) patients. The article is focused on analysis and review of possible mechanisms and benefits of cardiovascular risk reduction in DM2 with prescription of the antagonist of glucagonlike peptide 1 — liraglutide (Victoza®).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>сердечно-сосудистый риск</kwd><kwd>лираглутид</kwd><kwd>глюкагон-подобный пептид 1</kwd><kwd>адипокины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes</kwd><kwd>cardiovascular risk</kwd><kwd>liraglutide</kwd><kwd>glucagon-like peptide 1</kwd><kwd>adipokines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sattar N, Petrie MC, Zinman B, et al. Novel diabetes drugs and the cardiovascular specialist. Journal of the American College of Cardiology. 2017 May 22; 69 (21): 2646-56. 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