russjcardiolРоссийский кардиологический журналRussian Journal of Cardiology1560-40712618-7620«SILICEA-POLIGRAF» LLCrussjcardiol-2649Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWТОРАСЕМИД В ПРОФИЛАКТИКЕ ПРОГРЕССИРОВАНИЯ МИТРАЛЬНОЙ РЕГУРГИТАЦИИ И ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ В ПОСТИНФАРКТНОМ ПЕРИОДЕTORASEMIDE IN PREVENTION OF MITRAL REGURGITATION AND CHRONIC HEART FAILURE WORSENING IN POSTINFARCTION PERIODhttps://orcid.org/0000-0001-5287-5827АбдуллаевА. А.AbdullaevA. A.aligadzhia@yandex.ruhttps://orcid.org/0000-0003-2180-3868ИбрагимоваИ. Б.IbragimovaI. B.

Изумруд Бадировна Ибрагимова — ассистент кафедры поликлинической терапии

ibragimovaizumrud@gmail.comhttps://orcid.org/0000-0002-1280-1505ИсламоваУ. А.IslamovaU. A.

Уммет Абдулхакимовна Исламова — кандидат медицинских наук, доцент кафедры поликлинической терапии, кардиологии и общей врачебной практики

islamova_y_a@yandex.ruhttps://orcid.org/0000-0001-7141-0734ГафуроваР. М.GafurovaR. M.

Разият Магомедтагировна Гафурова — доктор медицинских наук, доцент кафедры поликлинической терапии, кардиологии и общей врачебной практики

gafurova-1965@mail.ruhttps://orcid.org/0000-0002-2262-1217БайтемироваН. НBaytemirovaN. N.baitemirovanaima@yandex.ruФГБОУ ВО Дагестанский государственный медицинский университет Минздрава РоссииРоссияDagestan State Medical University of the Ministry of HealthRussian Federation2018020620180597102Copyright © Абдуллаев А.А., Ибрагимова И.Б., Исламова У.А., Гафурова Р.М., Байтемирова Н.Н., 20182018Абдуллаев А.А., Ибрагимова И.Б., Исламова У.А., Гафурова Р.М., Байтемирова Н.Н.Abdullaev A.A., Ibragimova I.B., Islamova U.A., Gafurova R.M., Baytemirova N.N.This work is licensed under a Creative Commons Attribution 4.0 License.https://russjcardiol.elpub.ru/jour/article/view/2649

В обзоре приведены сведения о результатах научных исследований, проведенных для изучения влияния ишемической митральной регургитации (ИМР) на развитие и прогрессирование хронической сердечной недостаточности (ХСН). Рассмотрены возможности для использования торасемида с целью профилактики увеличения степени митральной регургитации, развития дезадаптивного ремоделирования сердца, уменьшения его электрической нестабильности, проявляющейся различными нарушениями ритма сердца, и предупреждения развития и прогрессирования ХСН. Выявлены преимущества торасемида перед фуросемидом при наличии застойной ХСН на фоне ИМР у пациентов, перенесших инфаркт миокарда.

In the review, the results of scientific research provided, conducted with aim to study influence of ischemic mitral regurgitation (IMR) on the development and progressionof chronic heart failure (CHF). The opportunities considered, of torasemide implementation in prevention of the raise of mitral regurgitation grade, development of desadaptive remodelling of the heart, decrease of its electrical instability that presents itself with various cardiac rhythm disorders, and of prevention ofdevelopment and progression of the CHF. Benefits of torasemide over furosemideare revealed in management of congestive CHF at the background of IMR inpostinfarction patients.

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The authors declare that there are no conflicts of interest present.