russjcardiolРоссийский кардиологический журналRussian Journal of Cardiology1560-40712618-7620«SILICEA-POLIGRAF» LLC10.15829/1560-4071-2017-12-84-89russjcardiol-2604Research ArticleКЛИНИКА И ФАРМАКОТЕРАПИЯCLINIC AND PHARMACOTHERAPYСОВРЕМЕННЫЕ ВОЗМОЖНОСТИ АНТИГИПЕРТЕНЗИВНОЙ ТЕРАПИИ: МЕСТО АЗИЛСАРТАНА МЕДОКСОМИЛАMODERN OPPORTUNITIES FOR ANTIHYPERTENSION THERAPY: THE PLACE OF AZILSARTAN MEDOXOMILСкибицкийВ. В.SkibitskyV. V.

Доктор медицинских наук, профессор,заведующийкафедрой госпитальной терапии.

Krasnodar

ФендриковаА. В.FendrikovaA. V.

Кандидат медицинских наук, доцент кафедры госпитальной терапии.

Краснодар

Krasnodar

alexandra2310@rambler.ruФГБОУ ВО Кубанский государственный медицинский университет Минздрава РоссииРоссияKubansky State Medical University of the Ministry of HealthRussian Federation2017171220170128489Copyright © Скибицкий В.В., Фендрикова А.В., 20172017Скибицкий В.В., Фендрикова А.В.Skibitsky V.V., Fendrikova A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://russjcardiol.elpub.ru/jour/article/view/2604

Современные подходы к антигипертензивной терапии подразумевают использование комбинации препаратов, обеспечивающих значимое позитивное влияние на показатели артериального давления (АД) в дневные и ночные часы, оптимизацию суточного профиля АД, достижение целевого уровня АД у большинства пациентов. Кроме того, немаловажно обеспечение органопротекции, в частности, вазопротекции. Всем этим критерием отвечает азилсартана медоксомил и его фиксированная комбинация с хлорталидоном. Комбинация азилсартан/хлорталидон обладает выраженным антигипертензивным эффектом, в том числе у пациентов с метаболическими нарушениями, способствует оптимизации АД в ночные часы, уменьшению сосудистой жесткости. Совокупность позитивных качеств данной комбинации позволяет широко использовать ее в реальной клинической практике для повышения эффективности лечения пациентов с артериальной гипертонией.

Modern approaches to antihypertension therapy suppose the usage of combination drugs, making significant positive influence on the values of systemic blood pressure (BP) in daily and nocturnal periods, optimization of 24-hour BP profile, achieved target BP in most of patients. Also, it is important to fulfill organ protection and vessel protection. To all these criteria does respond azilsartan medoxomil and its combination with chlorthalidone. The combination azilsartan/chlorthalidone shows serious antihypertension properties, including the patients with metabolic disorders, facilitates optimization of BP at night, decrease of vascular stiffness. Collection of positive properties of the combination makes it to apply broadly in real clinical practice to increase efficacy of hypertension patient’s management.

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The authors declare that there are no conflicts of interest present.