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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-1803</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURE</subject></subj-group></article-categories><title-group><article-title>ОСОБЕННОСТИ КЛИНИКИ, ДИАГНОСТИКИ И ЛЕЧЕНИЯ МИОПЕРИКАРДИТОВ И ДИФФУЗНЫХ МИОКАРДИТОВ</article-title><trans-title-group xml:lang="en"><trans-title>CLINIC CHARACTERISTICS, DIAGNOSTICS AND THERAPY OF MYOPERICARDITIS AND DIFFUSE MYOCARDITIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мравян</surname><given-names>С. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Mravjan</surname><given-names>S. R.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуревич</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gurevitch</surname><given-names>M. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2003</year></pub-date><pub-date pub-type="epub"><day>28</day><month>10</month><year>2003</year></pub-date><volume>0</volume><issue>5</issue><fpage>99</fpage><lpage>103</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мравян С.Р., Гуревич М.А., 2003</copyright-statement><copyright-year>2003</copyright-year><copyright-holder xml:lang="ru">Мравян С.Р., Гуревич М.А.</copyright-holder><copyright-holder xml:lang="en">Mravjan S.R., Gurevitch M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/1803">https://russjcardiol.elpub.ru/jour/article/view/1803</self-uri><abstract><p>В работе на основании собственного материала и литературных данных проанализировано течение вирусных миоперикардитов. Особое внимание уделено особенностям электрокардиографической динамики, выделены четыре стадии эволюции электрокардиографических признаков заболевания. Отмечено увеличение частоты геморрагических миоперикардитов, имеющих, по-видимому, вирусную природу.</p><p>Даны рекомендации по лечению больных миоперикардитом, прогноз которого позитивен. В то же время, прогноз диффузного миокардита остается неблагоприятным, а показания к его рациональному лечению - недостаточно установленными.</p></abstract><trans-abstract xml:lang="en"><p>In study on a basement of our own research and literature data clinical course of virus myopericarditis was analyzed. Special consideration has been given to characteristics of electrocardiographic indicators, four stages of evolution of cardiographic indicators of illness were emphasized. Increase of hemorrhagic myopericarditis frequency, evidently with virus nature, was noted. Recomendations for treatment in patients suffering from myopericarditis with positive prognosis were given. At the same time, prognosis of diffuse myocarditis remains negative, and indications for its rational treatment determined insufficiently.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>миокардит</kwd><kwd>миоперикардит</kwd><kwd>диагностика</kwd><kwd>лечение</kwd><kwd>прогноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocarditis</kwd><kwd>myopericarditis</kwd><kwd>diagnostics</kwd><kwd>prognosis</kwd><kwd>therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Soler-Soler J., Permanyer-Miralda G., Sagrista-Sauleda J.A. Systematic diagnostic approach to primary acute pericardial disease.//Cardiol. Clin. 1990. Vol. 8, N 4. P. 609-620.</mixed-citation><mixed-citation xml:lang="en">Soler-Soler J., Permanyer-Miralda G., Sagrista-Sauleda J.A. Systematic diagnostic approach to primary acute pericardial disease.//Cardiol. Clin. 1990. Vol. 8, N 4. P. 609-620.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гогин Е.Е. Новые возможности и задачи в дифференциальной диагностике перикардитов.//Клин. медицина. 1983. № 11. С. 24-30.</mixed-citation><mixed-citation xml:lang="en">Гогин Е.Е. Новые возможности и задачи в дифференциальной диагностике перикардитов.//Клин. медицина. 1983. № 11. С. 24-30.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Shabetai R. Acute pericarditis.//Cardiol. Clin. 1990. Vol. 8, N 4. P. 639-644.</mixed-citation><mixed-citation xml:lang="en">Shabetai R. Acute pericarditis.//Cardiol. Clin. 1990. Vol. 8, N 4. P. 639-644.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Yoneda S., Ohte N., Samoto Т., Kobayashi Т., et al. Two cases of viral myocarditis and one case of viral pericarditis.//Jap. Circul. J. 1982. Vol. 46. P. 1222-1226.</mixed-citation><mixed-citation xml:lang="en">Yoneda S., Ohte N., Samoto Т., Kobayashi Т., et al. Two cases of viral myocarditis and one case of viral pericarditis.//Jap. Circul. J. 1982. Vol. 46. P. 1222-1226.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">B. Maisch, A.D. Ristic, S. Pankuweit. Intrapericardial treatment of autoreactive pericardial effusion with triamcinolone.//Eur. Heart J. 2002. Vol. 23. P. 1503-1508.</mixed-citation><mixed-citation xml:lang="en">B. Maisch, A.D. Ristic, S. Pankuweit. Intrapericardial treatment of autoreactive pericardial effusion with triamcinolone.//Eur. Heart J. 2002. Vol. 23. P. 1503-1508.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Fujioka S., Koide H., Kitaura Y., et al. Molecular detection and differentiation of enteroviruses in endomyocardial biopsies and pericardial effusions from dilated cardiomyopathy and myocarditis.//Am. Heart J. 1996. Vol. 131. P. 760-765.</mixed-citation><mixed-citation xml:lang="en">Fujioka S., Koide H., Kitaura Y., et al. Molecular detection and differentiation of enteroviruses in endomyocardial biopsies and pericardial effusions from dilated cardiomyopathy and myocarditis.//Am. Heart J. 1996. Vol. 131. P. 760-765.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Гогин Е.Е. Перикардиты.//Кардиология. 1991. № 2. С. 80-86.</mixed-citation><mixed-citation xml:lang="en">Гогин Е.Е. Перикардиты.//Кардиология. 1991. № 2. С. 80-86.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Chia J.K.S., Jackson В. Myopericarditis due to parvovirus B19 in an adult.//Clin. Infect. Dis. 1996. Vol. 23. P. 200-201.</mixed-citation><mixed-citation xml:lang="en">Chia J.K.S., Jackson В. Myopericarditis due to parvovirus B19 in an adult.//Clin. Infect. Dis. 1996. Vol. 23. P. 200-201.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Orth Т., et al. Human parvovirus В19 infection associated with severe acute perimyocarditis in a 34-year-old man [letter].//Eur. Heart J. 1997. Vol. 18, N 3. P524-525.</mixed-citation><mixed-citation xml:lang="en">Orth Т., et al. Human parvovirus В19 infection associated with severe acute perimyocarditis in a 34-year-old man [letter].//Eur. Heart J. 1997. Vol. 18, N 3. P524-525.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Schonian U., Paul R., Gemsa D., Maisch B. Soluble interleukin-2 receptor, interleukin-6 and tumoral necrosis factor-alfa in inflammatory pericardial effusions. XVII Congr. of the Europ. Society of Card.//Eur. Heart J. 1995. Vol. 16. (abstr. Suppl.). ref. № 1711.</mixed-citation><mixed-citation xml:lang="en">Schonian U., Paul R., Gemsa D., Maisch B. Soluble interleukin-2 receptor, interleukin-6 and tumoral necrosis factor-alfa in inflammatory pericardial effusions. XVII Congr. of the Europ. Society of Card.//Eur. Heart J. 1995. Vol. 16. (abstr. Suppl.). ref. № 1711.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">D.H. Spodick. Intrapericardial treatment of persistent autoreactive pericarditis/myopericarditis and pericardial effusion.//Eur. Heart J. 2002. Vol. 23. P. 1481-1482.</mixed-citation><mixed-citation xml:lang="en">D.H. Spodick. Intrapericardial treatment of persistent autoreactive pericarditis/myopericarditis and pericardial effusion.//Eur. Heart J. 2002. Vol. 23. P. 1481-1482.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Бойцов С.А., Дерюгин М.В. Современные возможности диагностики неревматических миокардитов.//Consilium Medicum. 2002. Vol. 4. P. 117-124.</mixed-citation><mixed-citation xml:lang="en">Бойцов С.А., Дерюгин М.В. Современные возможности диагностики неревматических миокардитов.//Consilium Medicum. 2002. Vol. 4. P. 117-124.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Marcolongo R., Russo R., Laveder F., Noventa F., Agostini С. Immunosuppressive therapy prevents recurrent pericarditis.//J. Am. Coll. Cardiol. 1995. Vol. 26, N 5. P. 1276-1279.</mixed-citation><mixed-citation xml:lang="en">Marcolongo R., Russo R., Laveder F., Noventa F., Agostini С. Immunosuppressive therapy prevents recurrent pericarditis.//J. Am. Coll. Cardiol. 1995. Vol. 26, N 5. P. 1276-1279.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Гуревич М.А., Мравян С.Р., Григорьева Н.М. Особенности клиники, диагностики и лечения миоперикардитов.//Клин. медицина. 1999. № 7. С. 33-36.</mixed-citation><mixed-citation xml:lang="en">Гуревич М.А., Мравян С.Р., Григорьева Н.М. Особенности клиники, диагностики и лечения миоперикардитов.//Клин. медицина. 1999. № 7. С. 33-36.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Mason J.W., O'Connell J. B., Herskowitz N.E., et al. A clinical trial of immunosuppressive therapy for myocarditis.//New Engl. J. Med. 1995. Vol. 333. P. 269-275.</mixed-citation><mixed-citation xml:lang="en">Mason J.W., O'Connell J. B., Herskowitz N.E., et al. A clinical trial of immunosuppressive therapy for myocarditis.//New Engl. J. Med. 1995. Vol. 333. P. 269-275.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Hahn E.A., Hartz V.L., Moon Т.Е., et al. The Myocarditis Treatment Trial: Design, methods and patient enrolment.//Eur. Heart J. 1995. Vol. 16. P. 162-167.</mixed-citation><mixed-citation xml:lang="en">Hahn E.A., Hartz V.L., Moon Т.Е., et al. The Myocarditis Treatment Trial: Design, methods and patient enrolment.//Eur. Heart J. 1995. Vol. 16. P. 162-167.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Maisch В., Schonian U., Hengstenberg C., et al. Immunosuppressive treatment in autoreactive myocarditis -results from a controlled trial.//Postgrad. Med. J. 1994. Vol. 70 (Suppl. 1). S29-34.</mixed-citation><mixed-citation xml:lang="en">Maisch В., Schonian U., Hengstenberg C., et al. Immunosuppressive treatment in autoreactive myocarditis -results from a controlled trial.//Postgrad. Med. J. 1994. Vol. 70 (Suppl. 1). S29-34.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Grag A., Shiau J., Guyatt G. The ineffectiveness of immunosuppressive therapy in lymphocytic myocarditis.//Ann. Intern. Med. 1998. Vol. 129. P. 317-322.</mixed-citation><mixed-citation xml:lang="en">Grag A., Shiau J., Guyatt G. The ineffectiveness of immunosuppressive therapy in lymphocytic myocarditis.//Ann. Intern. Med. 1998. Vol. 129. P. 317-322.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Frustaci A., Pieroni M., Chimenti C. Immunosuppressive therapy in inflammatory cardiomyopathy.//Eur. Heart J. 2002. Vol. 4 (Suppl. l). P. 169-173.</mixed-citation><mixed-citation xml:lang="en">Frustaci A., Pieroni M., Chimenti C. Immunosuppressive therapy in inflammatory cardiomyopathy.//Eur. Heart J. 2002. Vol. 4 (Suppl. l). P. 169-173.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Kuhl U., Pauschinger M., Noutsias M., et al. Diagnosis and treatment of patients with virus induced inflammatory cardiomyopathy.//Eur. Heart J. 2002. Vol. 4 (Suppl. l). P. 173-180.</mixed-citation><mixed-citation xml:lang="en">Kuhl U., Pauschinger M., Noutsias M., et al. Diagnosis and treatment of patients with virus induced inflammatory cardiomyopathy.//Eur. Heart J. 2002. Vol. 4 (Suppl. l). P. 173-180.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Miric M., Vasiljevic J., Bojic M., et al. Long-term follow up of patients with dilated heart muscle disease treated with human leucocytic interferon alpha or thymic hormones initial results.//Heart. 1996. Vol. 75. P. 596-601.</mixed-citation><mixed-citation xml:lang="en">Miric M., Vasiljevic J., Bojic M., et al. Long-term follow up of patients with dilated heart muscle disease treated with human leucocytic interferon alpha or thymic hormones initial results.//Heart. 1996. Vol. 75. P. 596-601.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Camargo P.R., Snitcowsky R., da Luz P.L., et al. Favorable effects of immunosuppressive therapy in children with dilated cardiomyopathy and active myocarditis.//Pediatric Cardiol. 1995. Vol. 16. P. 61-8.</mixed-citation><mixed-citation xml:lang="en">Camargo P.R., Snitcowsky R., da Luz P.L., et al. Favorable effects of immunosuppressive therapy in children with dilated cardiomyopathy and active myocarditis.//Pediatric Cardiol. 1995. Vol. 16. P. 61-8.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Schmaltz A.A., Demel K.P., Kallenberg R., et al. Immunosuppressive therapy of chronic myocarditis in children: Three cases and the design of a randomized prospective trial of therapy.//Pediatric Cardiol. 1998. Vol. 19. P. 235-239.</mixed-citation><mixed-citation xml:lang="en">Schmaltz A.A., Demel K.P., Kallenberg R., et al. Immunosuppressive therapy of chronic myocarditis in children: Three cases and the design of a randomized prospective trial of therapy.//Pediatric Cardiol. 1998. Vol. 19. P. 235-239.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Maisch В., Hufnagel G., Schonian U., Hengstenberg. The European Study of Epidemiology and Treatment of Cardiac Inflammatory Disease (ESETCID).//Eur. Heart J. 1995. Vol. 16 (Suppl. 0). P. 173-175.</mixed-citation><mixed-citation xml:lang="en">Maisch В., Hufnagel G., Schonian U., Hengstenberg. The European Study of Epidemiology and Treatment of Cardiac Inflammatory Disease (ESETCID).//Eur. Heart J. 1995. Vol. 16 (Suppl. 0). P. 173-175.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
