russjcardiolРоссийский кардиологический журналRussian Journal of Cardiology1560-40712618-7620«SILICEA-POLIGRAF» LLC10.15829/1560-4071-2017-7-171-177russjcardiol-1664Research ArticleОБЗОРЫ ЛИТЕРАТУРЫREVIEWСОВРЕМЕННАЯ ФАРМАКОТЕРАПИЯ ФИБРИЛЛЯЦИИ ПРЕДСЕРДИЙSTATE OF THE ART PHARMACOLOGICAL THERAPY FOR ATRIAL FIBRILLATIONКанорскийС. Г.KanorskyS. G.

Канорский Сергей Григорьевич— доктор медицинских наук профессор, зав. кафедрой терапии № 2 ФПК и ППС

kanorskysg@mail.ruКоваленкоЮ. С.KovalenkoYu. S.

Кандидат медицинских наук, ассистент кафедры эндокринологии ФПК и ППС и ППС

ФГБОУ ВО Кубанский государственный медицинский университет Минздрава РоссииРоссияKubansky State Medical University of the Ministry of HealthRussian Federation20172308201707171177Copyright © Канорский С.Г., Коваленко Ю.С., 20172017Канорский С.Г., Коваленко Ю.С.Kanorsky S.G., Kovalenko Y.S.This work is licensed under a Creative Commons Attribution 4.0 License.https://russjcardiol.elpub.ru/jour/article/view/1664

Фармакотерапия остается доминирующим способом лечения больных с фибрилляцией предсердий (ФП). Ведение пациентов с ФП включает в себя решение о выборе между урежением частоты желудочковых сокращений и поддержанием синусового ритма. Во втором случае применяются антиаритмические препараты, выбор которых в первую очередь определяется соображениями безопасности и зависит от индивидуальных характеристик пациентов. В статье дана краткая характеристика эффективности и безопасности собственно антиаритмических и иных препаратов для поддержания синусового ритма у больных с ФП. Новые данные свидетельствуют о возможности снижения риска инсульта и смертности, прекращении антикоагулянтной терапии при более агрессивном поддержании синусового ритма.

Pharmacological therapy remains the primary approach to atrial fibrillation (AF). Management of all AF patients includes the decision on rate or rhythm control. The latter means antiarrhythmic drugs application that are being selected primarily by safety reasons and depend on individual characteristics of patients. The article presents a brief description of efficacy and safety of antiarrhythmics themselves and other drugs for sinus rhythm control in AF. Novel data shows possibility to decrease stroke risk and mortality, and to cease anticoagulation in more thorough sinus rhythm retention.

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The authors declare that there are no conflicts of interest present.