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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2014-12-85-95</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-165</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>ВОЗМОЖНОСТЬ ПРИМЕНЕНИЯ НОВЫХ ПЕРОРАЛЬНЫХ АНТИКОАГУЛЯНТОВ У ПАЦИЕНТОВ ПРИ ПРОВЕДЕНИИ АБЛАЦИИ ПО ПОВОДУ ФИБРИЛЛЯЦИИ ПРЕДСЕРДИЙ</article-title><trans-title-group xml:lang="en"><trans-title>POSSIBILITY OF NOVEL ORAL ANTICOAGULANTS USAGE DURING ABLATION IN ATRIAL FIBRILLATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Татарский</surname><given-names>Б. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tatarsky</surname><given-names>B. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, руководитель НИЛ нарушений ритма сердца</p></bio><email xlink:type="simple">romancer@cardio.tsu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баталов</surname><given-names>Р. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Batalov</surname><given-names>R. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Старший научный сотрудник отделения хирургического лечения сложных нарушений ритма сердца и электрокардиостимуляции</p></bio><email xlink:type="simple">romancer@cardio.tsu.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доктор медицинских наук, профессор, чл.-корр. РАН, руководитель отделения хирургического лечения сложных нарушений ритма сердца и электрокардиостимуляции, заместитель директора по научной и лечебной работе</p></bio><email xlink:type="simple">romancer@cardio.tsu.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральный медицинский исследовательский центр им. В. А. Алмазова, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Medical Research Centre named after. V. A. Almazov, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт кардиологии, Томск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific-Research Institute of Cardiology, Tomsk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2014</year></pub-date><volume>0</volume><issue>12</issue><fpage>85</fpage><lpage>95</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Татарский Б.А., Баталов Р.Е., Попов С.В., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Татарский Б.А., Баталов Р.Е., Попов С.В.</copyright-holder><copyright-holder xml:lang="en">Tatarsky B.A., Batalov R.E., Popov S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/165">https://russjcardiol.elpub.ru/jour/article/view/165</self-uri><abstract><p>В обзоре представлены современные подходы к антикоагулянтной терапии при проведении катетерной радиочастотной аблации фибрилляции предсердий. Обсуждаются возможности различных вариантов перипроцедурального использования варфарина, показаны некоторые результаты исследований, эффективность и безопасность ряда новых пероральных антикоагулянтов при катетерной аблации.</p></abstract><trans-abstract xml:lang="en"><p>The review provides the data on contemporary approaches to anticoagulant therapy during catheter radiofrequency ablation of atrial fibrillation. The opportunities are discussed for various types of periprocedural use of warfarin, and the results mentioned for the efficacy and safety of novel oral anticoagulants in catheter ablation.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>катетерная аблация</kwd><kwd>фибрилляция предсердий</kwd><kwd>варфарин</kwd><kwd>новые пероральные антикоагулянты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>catheter ablation</kwd><kwd>atrial fibrillation</kwd><kwd>warfarin</kwd><kwd>novel oral anticoagulants</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wolf P, Abbott R, Kannel W. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:983–88.</mixed-citation><mixed-citation xml:lang="en">Wolf P, Abbott R, Kannel W. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:983–88.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Camm J, Up G, De Caterina R, et al. Atrial fibrillation (management of) 2010 and focused update (2012), ESC clinical practice guidelines. Eur Heart J 2012;33:2719-47.</mixed-citation><mixed-citation xml:lang="en">Camm J, Up G, De Caterina R, et al. Atrial fibrillation (management of) 2010 and focused update (2012), ESC clinical practice guidelines. Eur Heart J 2012;33:2719-47.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Calkins H, Kuck K, Cappato R, et al. 2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. Europace 2012;14:528–606.</mixed-citation><mixed-citation xml:lang="en">Calkins H, Kuck K, Cappato R, et al. 2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. Europace 2012;14:528–606.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kneeland P, Fang M. Trends in catheter ablation for atrial fibrillation in the United States. J Hosp Med. 2009;4:E1–E5.</mixed-citation><mixed-citation xml:lang="en">Kneeland P, Fang M. Trends in catheter ablation for atrial fibrillation in the United States. J Hosp Med. 2009;4:E1–E5.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Hart R, Benavente O, McBride R. Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis. Ann Intern Med. 1999;131:492.</mixed-citation><mixed-citation xml:lang="en">Hart R, Benavente O, McBride R. Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis. Ann Intern Med. 1999;131:492.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Smerli G, Lynch S, Fertel S, et al. The difficulties in anticoagulation therapy with warfarin. J Thromb Thrombolysis 2009;27(3):293-9.</mixed-citation><mixed-citation xml:lang="en">Smerli G, Lynch S, Fertel S, et al. The difficulties in anticoagulation therapy with warfarin. J Thromb Thrombolysis 2009;27(3):293-9.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Capodanno D, Capranzano P, Giacchi G, et al. Novel oral anticoagulants versus warfarin in non-valvular atrial fibrillation: A meta-analysis of 50,578 patients. International journal of Cardiology 2012;34(5):176-185.</mixed-citation><mixed-citation xml:lang="en">Capodanno D, Capranzano P, Giacchi G, et al. Novel oral anticoagulants versus warfarin in non-valvular atrial fibrillation: A meta-analysis of 50,578 patients. International journal of Cardiology 2012;34(5):176-185.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Dentali F, Riva N, Crowther M, et al. Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature. Circulation 2012;126:2381-91.</mixed-citation><mixed-citation xml:lang="en">Dentali F, Riva N, Crowther M, et al. Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature. Circulation 2012;126:2381-91.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mardigyan V, Verma A, Birnie D, et al. Anticoagulation Management Preand Post-AF ablation: A survey of Canadian centers. Can J Cardiol. 2012;29:219–23.</mixed-citation><mixed-citation xml:lang="en">Mardigyan V, Verma A, Birnie D, et al. Anticoagulation Management Preand Post-AF ablation: A survey of Canadian centers. Can J Cardiol. 2012;29:219–23.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Tapanainen J, Braunschweig R, Schwieler J, et al. Continuous warfarin therapy is sate and feasible in catheter ablation of atrial fibrillation. Scand Cardiovasc J 2013;47(2):109-13.</mixed-citation><mixed-citation xml:lang="en">Tapanainen J, Braunschweig R, Schwieler J, et al. Continuous warfarin therapy is sate and feasible in catheter ablation of atrial fibrillation. Scand Cardiovasc J 2013;47(2):109-13.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Birnie D, Healey J, Wells G, et al. BRUISE CONTROL Investigators. Pacemaker or defibrillator surgery without interruption of anticoagulation. N Engl J Med. 2013;368:2084–93.</mixed-citation><mixed-citation xml:lang="en">Birnie D, Healey J, Wells G, et al. BRUISE CONTROL Investigators. Pacemaker or defibrillator surgery without interruption of anticoagulation. N Engl J Med. 2013;368:2084–93.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Di Biase L, Bunkhardt J, Mohanty P, et al. Periprocedural stroke and management of major bleeding complications in patients undergoing catheter ablation of atrial fibrillation: the impact of periprocedural therapeutic international normalized ratio. Circulation 2010;121:2550–56.</mixed-citation><mixed-citation xml:lang="en">Di Biase L, Bunkhardt J, Mohanty P, et al. Periprocedural stroke and management of major bleeding complications in patients undergoing catheter ablation of atrial fibrillation: the impact of periprocedural therapeutic international normalized ratio. Circulation 2010;121:2550–56.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Santangeli P, Di Biase L, Horton R, et al. Ablation of atrial fibrillation under therapeutic warfarin reduces periprocedural complications: Evidence from a meta-analysis. Circ Arrhythm Electrophysiol 2012;5:302–11.</mixed-citation><mixed-citation xml:lang="en">Santangeli P, Di Biase L, Horton R, et al. Ablation of atrial fibrillation under therapeutic warfarin reduces periprocedural complications: Evidence from a meta-analysis. Circ Arrhythm Electrophysiol 2012;5:302–11.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Periprocedural stroke and bleeding complications in patents undergoing catheter ablation of atrial fibrillation with different anticoagulation management: results from the Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation (COMPARE) randomized trial. Circulation 2014;129{25):2638-44.</mixed-citation><mixed-citation xml:lang="en">Periprocedural stroke and bleeding complications in patents undergoing catheter ablation of atrial fibrillation with different anticoagulation management: results from the Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation (COMPARE) randomized trial. Circulation 2014;129{25):2638-44.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Healey J, Eikelboom J, Douketis J. Investigators. Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial. Circulation. 2012:126:343-348.</mixed-citation><mixed-citation xml:lang="en">Healey J, Eikelboom J, Douketis J. Investigators. Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial. Circulation. 2012:126:343-348.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Diagnostics and treatment of atrial fibrillation. In: The Recommendations of the Russian Society of Cardiology, Pan-Russian Scientific Society of Clinical Electrophysiology, Arrhythmology and Cardiac Pacing, and the Association of Cardiovascular Surgeons of Russia. Moscow. 2012. 100 pp. Russian (Диагностика и лечение фибрилляции предсердий: рекомендации РКО. ВНОА и АССХ. М., 2012. 100 с.)</mixed-citation><mixed-citation xml:lang="en">Diagnostics and treatment of atrial fibrillation. In: The Recommendations of the Russian Society of Cardiology, Pan-Russian Scientific Society of Clinical Electrophysiology, Arrhythmology and Cardiac Pacing, and the Association of Cardiovascular Surgeons of Russia. Moscow. 2012. 100 pp. Russian (Диагностика и лечение фибрилляции предсердий: рекомендации РКО. ВНОА и АССХ. М., 2012. 100 с.)</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Heidbuchel H, Verhamme R, Alings M, et al. EHRA Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation: executive summary. Eur Heart J 2013; 34(27):2094-106.</mixed-citation><mixed-citation xml:lang="en">Heidbuchel H, Verhamme R, Alings M, et al. EHRA Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation: executive summary. Eur Heart J 2013; 34(27):2094-106.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Lakkireddy D, Reddy Y, Di Biase L, et al. Feasibility and safety of dabigatran versus warfarin for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective registry. J Am Coll Cardiol 2012;59(13):1168-74.</mixed-citation><mixed-citation xml:lang="en">Lakkireddy D, Reddy Y, Di Biase L, et al. Feasibility and safety of dabigatran versus warfarin for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective registry. J Am Coll Cardiol 2012;59(13):1168-74.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Winkle R, Mead H, Engel G et al. Safety of Dabigatran Versus Warfarin for Periprocedural Anticoagulation in Patients Undergoing Ablation for Atrial Fibrillation. J Am Coll Cardiol 2012;60(12): 1118-19.</mixed-citation><mixed-citation xml:lang="en">Winkle R, Mead H, Engel G et al. Safety of Dabigatran Versus Warfarin for Periprocedural Anticoagulation in Patients Undergoing Ablation for Atrial Fibrillation. J Am Coll Cardiol 2012;60(12): 1118-19.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Kim J, She F, Jongnarangsin K, et al. Dabigatran vs. warfarin for radiofrequency catheter ablation of atrial fibrillation. Heart Rhythm. 2012;10:483–9.</mixed-citation><mixed-citation xml:lang="en">Kim J, She F, Jongnarangsin K, et al. Dabigatran vs. warfarin for radiofrequency catheter ablation of atrial fibrillation. Heart Rhythm. 2012;10:483–9.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Pandya B, Schwartz L, Shah N, et al. Does Pre-procedural Dabigatran The Need Of Higher Heparin Dosage During Atrial Fibrillation Ablation Procedure? Poster Session VI, Heart Rhythm,2013.</mixed-citation><mixed-citation xml:lang="en">Pandya B, Schwartz L, Shah N, et al. Does Pre-procedural Dabigatran The Need Of Higher Heparin Dosage During Atrial Fibrillation Ablation Procedure? Poster Session VI, Heart Rhythm,2013.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Nin T, Sairaku A, Yoshida Y et al. A randomized controlled trial of dabigatran versus warfarin for periablation anticoagulation in patients undergoing ablation of atrial fibrillation. Pacing Clin Electrophysiol. 2013;36:172–9.</mixed-citation><mixed-citation xml:lang="en">Nin T, Sairaku A, Yoshida Y et al. A randomized controlled trial of dabigatran versus warfarin for periablation anticoagulation in patients undergoing ablation of atrial fibrillation. Pacing Clin Electrophysiol. 2013;36:172–9.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Bassiouny M, Saliba W, Rickard J, et al. Use of dabigatran for periprocedural anticoagulation in patients undergoing catheter ablation for atrial fibrillation. Circ Arrhythm Electrophysiol. 2013;6:460–6.</mixed-citation><mixed-citation xml:lang="en">Bassiouny M, Saliba W, Rickard J, et al. Use of dabigatran for periprocedural anticoagulation in patients undergoing catheter ablation for atrial fibrillation. Circ Arrhythm Electrophysiol. 2013;6:460–6.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Arshad A, Buch E, Hamam I, et al. Comparative safety of anticoagulation strategies periablation for atrial fibrillation: Data from a large multicenter study. Heart Rhythm 2013, Abstract #AB33-02.</mixed-citation><mixed-citation xml:lang="en">Arshad A, Buch E, Hamam I, et al. Comparative safety of anticoagulation strategies periablation for atrial fibrillation: Data from a large multicenter study. Heart Rhythm 2013, Abstract #AB33-02.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Providencia R, Albenque J, Combes S, et al. Safety and efficacy of dabigatran versus warfarin in patients undergoing catheter ablation of atrial fibrillation: a systematic review and meta-analysis. Heart 2014;100:324–35.</mixed-citation><mixed-citation xml:lang="en">Providencia R, Albenque J, Combes S, et al. Safety and efficacy of dabigatran versus warfarin in patients undergoing catheter ablation of atrial fibrillation: a systematic review and meta-analysis. Heart 2014;100:324–35.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Hohnloser S, Camm J. Safety and efficacy of dabigatran etexilate during catheter ablation of atrial fibrillation: a meta-analysis of the literature. Europace 2013;15(10):1407-11.</mixed-citation><mixed-citation xml:lang="en">Hohnloser S, Camm J. Safety and efficacy of dabigatran etexilate during catheter ablation of atrial fibrillation: a meta-analysis of the literature. Europace 2013;15(10):1407-11.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Di Biase L, Burkhardt D, Gilbert G, et al. Dabigratan Has a Higher Risk of Left Atrial Appendage Thrombus Formation in Patients With Af When Compared to Warfarin and Rivaroxaban. http://www.abstractsonline.com /Plan/ViewAbstract. Dallas, 2013.</mixed-citation><mixed-citation xml:lang="en">Di Biase L, Burkhardt D, Gilbert G, et al. Dabigratan Has a Higher Risk of Left Atrial Appendage Thrombus Formation in Patients With Af When Compared to Warfarin and Rivaroxaban. http://www.abstractsonline.com /Plan/ViewAbstract. Dallas, 2013.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Steinberg B, Hasselblad V, Atwater B, et al. Dabigatran for periprocedural anticoagulation following radiofrequency ablation for atrial fibrillation: a meta-analysis of observational studies.J.Interv.Card. Electrophysiol. 2013; 37:213–21.</mixed-citation><mixed-citation xml:lang="en">Steinberg B, Hasselblad V, Atwater B, et al. Dabigatran for periprocedural anticoagulation following radiofrequency ablation for atrial fibrillation: a meta-analysis of observational studies.J.Interv.Card. Electrophysiol. 2013; 37:213–21.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Kaess B, Ammar S, Reents T, et al. Comparison of Safety of Left Atrial Catheter Ablation Procedures for Atrial Arrhythmias under Continuous Anticoagulation with Apixaban versus Phenprocoumon. Published Online: October 11, 2014.</mixed-citation><mixed-citation xml:lang="en">Kaess B, Ammar S, Reents T, et al. Comparison of Safety of Left Atrial Catheter Ablation Procedures for Atrial Arrhythmias under Continuous Anticoagulation with Apixaban versus Phenprocoumon. Published Online: October 11, 2014.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Lakkireddy D, Reddy M, Swarup V, et al. Uninterrupted rivaroxaban vs. warfarin for periprocedural anticoagulation during atrial fibrillation ablation: A multicentre experience. Heart Rhythm 2013, Abstract #AB33-01.</mixed-citation><mixed-citation xml:lang="en">Lakkireddy D, Reddy M, Swarup V, et al. Uninterrupted rivaroxaban vs. warfarin for periprocedural anticoagulation during atrial fibrillation ablation: A multicentre experience. Heart Rhythm 2013, Abstract #AB33-01.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Dillier R, Ammar S, Reents T et al. Safety and Efficacy of Continuous Periprocedural Rivaroxaban for Patients Undergoing Catheter Ablation Procedures: A Retrospective Registry Analysis. Heart Rhythm, 2013, Abstract #PO03-127.</mixed-citation><mixed-citation xml:lang="en">Dillier R, Ammar S, Reents T et al. Safety and Efficacy of Continuous Periprocedural Rivaroxaban for Patients Undergoing Catheter Ablation Procedures: A Retrospective Registry Analysis. Heart Rhythm, 2013, Abstract #PO03-127.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Lakkireddy D, Reddy Y, Di Biase L, et al. Feasibility and safety of uninterrupted rivaroxaban for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective study. J Am Coll Cardiol. 2014;63:982–8.</mixed-citation><mixed-citation xml:lang="en">Lakkireddy D, Reddy Y, Di Biase L, et al. Feasibility and safety of uninterrupted rivaroxaban for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective study. J Am Coll Cardiol. 2014;63:982–8.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Providencia R, Marijon E, Albenque J-P, et al. Rivaroxaban and Dabigatran in Patients Undergoing Catheter Ablation of Atrial Fibrillation. Europace. 2014;16(8):1137-44.</mixed-citation><mixed-citation xml:lang="en">Providencia R, Marijon E, Albenque J-P, et al. Rivaroxaban and Dabigatran in Patients Undergoing Catheter Ablation of Atrial Fibrillation. Europace. 2014;16(8):1137-44.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Siklody C, Deneke T, Hocini M, et al. Incidence of asymptomatic intracranial embolic events after pulmonary vein isolation: comparison of different atrial fibrillation ablation technologies in a multicenter study. J Am Coll Cardiol. 2011;58(7):681-8.</mixed-citation><mixed-citation xml:lang="en">Siklody C, Deneke T, Hocini M, et al. Incidence of asymptomatic intracranial embolic events after pulmonary vein isolation: comparison of different atrial fibrillation ablation technologies in a multicenter study. J Am Coll Cardiol. 2011;58(7):681-8.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Haines D, Stewart M, Dahlberg S, et al. Microembolism and catheter ablation I: A comparison of irrigated radiofrequency and multielectrode-phased radiofrequency catheter ablation of pulmonary vein ostia. Circ Arrhythm Electrophysiol 2013; 6:16–22.</mixed-citation><mixed-citation xml:lang="en">Haines D, Stewart M, Dahlberg S, et al. Microembolism and catheter ablation I: A comparison of irrigated radiofrequency and multielectrode-phased radiofrequency catheter ablation of pulmonary vein ostia. Circ Arrhythm Electrophysiol 2013; 6:16–22.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Bohnen M, Stevenson W, Tedrow U, et al. Incidence and predictors of major complications from contemporary catheter ablation to treat cardiac arrhythmias. Heart Rhythm. 2011;8:1661–66.</mixed-citation><mixed-citation xml:lang="en">Bohnen M, Stevenson W, Tedrow U, et al. Incidence and predictors of major complications from contemporary catheter ablation to treat cardiac arrhythmias. Heart Rhythm. 2011;8:1661–66.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Nagy-Balo E, Tint D, Clemens M, et al. Transcranial measurement of cerebral microembolic signals during pulmonary vein isolation: a comparison of two ablation techniques. Circ Arrhythm Electrophysiol. 2013;6:473–80.</mixed-citation><mixed-citation xml:lang="en">Nagy-Balo E, Tint D, Clemens M, et al. Transcranial measurement of cerebral microembolic signals during pulmonary vein isolation: a comparison of two ablation techniques. Circ Arrhythm Electrophysiol. 2013;6:473–80.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Ichiki H, Oketani N, Ishida S, et al. The incidence of asymptomatic cerebral microthromboembolism after atrial fibrillation ablation: comparison of warfarin and dabigatran. Pacing and Clinical Electrophysiology 2013;36(111):1328-35.</mixed-citation><mixed-citation xml:lang="en">Ichiki H, Oketani N, Ishida S, et al. The incidence of asymptomatic cerebral microthromboembolism after atrial fibrillation ablation: comparison of warfarin and dabigatran. Pacing and Clinical Electrophysiology 2013;36(111):1328-35.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
