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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15829/1560-4071-2014-9-43-47</article-id><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-142</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>НАРУШЕНИЯ СНА И РИСК РАЗВИТИЯ ИНФАРКТА МИОКАРДА И ИНСУЛЬТА У МУЖЧИН Г. НОВОСИБИРСКА</article-title><trans-title-group xml:lang="en"><trans-title>SLEEP DISORDERS AND THE RISK OF MYOCARDIAL INFARCTION AND STROKE IN MEN OF NOVOSIBIRSK CITY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., профессор, руководитель межведомственной лаборатории эпидемиологии, лаборатории психологических и социологических проблем терапевтических заболеваний</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Громова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gromova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., н. с. межведомственной лаборатории эпидемиологии, лаборатории психологических и социологических проблем терапевтических заболеваний</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гагулин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gagulin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>с. н.с. межведомственной лаборатории эпидемиологии, лаборатории психологических и социологических проблем терапевтических заболеваний</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафарова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м.н., н. с. межведомственной лаборатории эпидемиологии, лаборатории психологических и социологических проблем терапевтических заболеваний</p></bio><email xlink:type="simple">valery.gafarov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панов</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Panov</surname><given-names>D. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м.н., н. с. межведомственной лаборатории эпидемиологии, лаборатории психологических и социологических проблем терапевтических заболеваний</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБУ Научно-исследовательский институт терапии и профилактической медицины Сибирского отделения РАМН, лаборатория социологических и психологических проблем терапевтических заболеваний; Межведомственная лаборатория эпидемиологии сердечно-сосудистых заболеваний Сибирского отделения РАМН, Новосибирск, Россия.<country>Россия</country></aff><aff xml:lang="en">FSBI Scientific-Research Institute of Therapy and Prevention of the SD RAMS, laboratory of sociology and psychology of internal diseases; Interdepartmental Laboratory of Cardiovascular Epidemiology of the SD RAMS, Novosibirsk, Russia.<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2014</year></pub-date><volume>0</volume><issue>9</issue><fpage>43</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гафаров В.В., Громова Е.А., Гагулин И.В., Гафарова А.В., Панов Д.О., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Гафаров В.В., Громова Е.А., Гагулин И.В., Гафарова А.В., Панов Д.О.</copyright-holder><copyright-holder xml:lang="en">Gafarov V.V., Gromova E.A., Gagulin I.V., Gafarova A.V., Panov D.O.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/142">https://russjcardiol.elpub.ru/jour/article/view/142</self-uri><abstract><sec><title>Цель</title><p>Цель. Определить риск развития инфаркта миокарда (ИМ) и инсульта у мужчин трудоспособного возраста (25–64 лет) с нарушениями сна в течение 14-летнего периода.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В рамках III скрининга программы ВОЗ “MONICApsychosocial” обследована случайная репрезентативная выборка мужчин 25–64 лет г. Новосибирска в 1994г (n=657, ср.возраст — 44,3±0,4 года, респонс — 82,1%). Программа скринирующего обследования включала регистрацию социально — демографических данных, определение нарушения сна (шкала Jenkins C. D.). За 14-летний период было выявлено 30 случаев ИМ и 22 случая инсульта. Статистический анализ проводился с помощью пакета программ SPSS версия 11,5. Использовали критерий χ2 Пирсона, для оценки Hazard ratio (HR) — Cox-regression. Достоверность во всех видах анализа была принята при уровне значимости p≤0,05.</p></sec><sec><title>Результаты</title><p>Результаты. Уровень нарушений сна в мужской популяции 25–64 лет составил 48,3%; оценка сна “удовлетворительно” — 39,6%, “плохо” — 7,6%, “очень плохо” — 1,1%. Дали оценку сна “хорошо” — 46,2%, “очень хорошо” — 5,6%. Среди мужчин с возникшим ИМ оценка сна “хорошо” составила 36,8%, “удовлетворительно” — 44,7%, “плохо” — 18,4% (χ2=2,402, n=4, р&gt;0,05). Среди лиц, перенесших инсульт, у 47,1% оценка сна — “хорошо”, у 23,5% — “удовлетворительно”, и 29,4% отмечают плохой сон (χ2=6,234, υ=2, р&lt;0,05). В регрессионном анализе Кокса риск ИМ в течение 5-летнего контрольного периода у лиц 25–64 лет с нарушением сна был HR=2,4, 10-летнего периода HR= 2,6 и в течение 14-летнего HR=2,3; риск инсульта в течение первых 5 лет был выше у мужчин с нарушением сна: HR=3,9, через 10 лет HR — 2,72, через 14 лет HR-1,5. Огромное влияние на риск ИМ и инсульта среди мужчин, испытывающих проблемы со сном, оказал семейный статус. Риск ИМ и инсульта был выше среди мужчин, никогда не состоявших в браке, разведённых и овдовевших. Наибольшему риску ИМ и инсульта были подвержены мужчины с нарушением сна, имеющие начальное образование, а также занимающиеся физическим трудом разной степени тяжести.</p></sec><sec><title>Заключение</title><p>Заключение. Нарушение сна представляет собой сильнодействующий психосоциальный фактор риска развития инфаркта миокарда и инсульта.</p></sec><sec><title> </title><p> </p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To estimate the risk of myocardial infarction (MI) and stroke in economically- active men (25-64 y.o.) with sleep disorders during 14-years period. Material and methods. In the 3rd screening for WHO program "MONICA- psychosocial" the random relevant selection was studied of the men 25-64 y.o. in Novosibirsk in the year 1994 (n=657, mean age 44,3±0,4, response — 82,1%). The program of screeing examination included the registration of social and demographic data, sleep disorders assessment with Jenkins C. D. score. During 14-year perion 30 MIs and 22 strokes registered. Statistical analysis was done with SPSS v. 11.5 software. We used Pirson %2 criteria, and for Hazard Ratio (HR) — Cox-regression. Reliability in all types of analysis was with the cut-off p&lt;0,05. Results. The prevalence of sleep disorders in men 25-64 y.o. was 48,3%; "satisfactory" self sleep assessment was in 39,6%; "bad" — 7,6%; "very bad" — 1,1%. As "good" their sleep marked 46,2% and as "very good" — 5,6%. In men with the MI developed "good" sleep mark was 36,8%, "satisfactory" — 44,7%, "bad" — 18,4% (x2=2,402, v=4, р&gt;0,05). In those developed stroke in 47,1% the mark was "good", in 23,5% — "satisfactory", and 29,4% marked bad sleep (x2=6,234, u=2, р&lt;0,05).</p><p>In Cox Regression the MI 5-year risk in persons of 25-64 y.o. with sleep disorders was HR=2,4, during 10 years — HR=2,6, and during 14 years HR=2,3; for stroke, respectively, 3,9; 2,72; 1,5.</p><p>A serious influence on the MI and stroke risk among men having sleep disorders, made family status. MI and stroke risk is much higher in single, divorced or widowed. The highest risk of MI and stroke had men with sleep disorders having low education level and on strenuous physical labour.</p></sec><sec><title>Conclusion</title><p>Conclusion. Sleep disorders is important an influencing psychosocial risk factor for MI and stroke.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>нарушение сна</kwd><kwd>риск</kwd><kwd>инфаркт миокарда</kwd><kwd>инсульт</kwd><kwd>мужская популяция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sleep disorders</kwd><kwd>risk</kwd><kwd>myocardial infarction</kwd><kwd>stroke</kwd><kwd>male cohort</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nagai M, Hoshide S, Kario K. Sleep Duration as a Risk Factor for Cardiovascular Disease- a Review of the Recent Literature. Curr Cardiol Rev. 2010; 6: 54-61.</mixed-citation><mixed-citation xml:lang="en">Nagai M, Hoshide S, Kario K. Sleep Duration as a Risk Factor for Cardiovascular Disease- a Review of the Recent Literature. 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