<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">russjcardiol</journal-id><journal-title-group><journal-title xml:lang="ru">Российский кардиологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Cardiology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1560-4071</issn><issn pub-type="epub">2618-7620</issn><publisher><publisher-name>«SILICEA-POLIGRAF» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">russjcardiol-1233</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>КОРРЕКЦИЯ ПОРАЖЕНИЙ СОСУДИСТОГО РУСЛА ПРИ АРТЕРИАЛЬНОЙ ГИПЕРТОНИИ С АКЦЕНТОМ НА ПЕРИНДОПРИЛ</article-title><trans-title-group xml:lang="en"><trans-title>VASCULAR INJURY CORRECTION IN ARTERIAL HYPERTENSION: FOCUS ON PERINDOPRIL</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беленков</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Belenkov</surname><given-names>Yu. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>член-корр. РАН, академик РАМН, профессор, д.м.н., зав. кафедрой</p></bio><email xlink:type="simple">shan84@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Привалова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Privalova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры</p></bio><email xlink:type="simple">shan84@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данилогорская</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Danilogorskaya</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры</p></bio><email xlink:type="simple">shan84@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Железных</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zheleznykh</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., ведущий научный сотрудник</p></bio><email xlink:type="simple">shan84@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щендрыгина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchendrygina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., ст.научный сотрудник</p></bio><email xlink:type="simple">shan84@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра госпитальной терапии № 1 л/ф Первого московского государственного медицинского университета им. И.М. Сеченова, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Hospital Therapy Department No. 1, Therapy Faculty, I.M. Sechenov First Moscow State Medical University, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>лаборатория «Хрономедицина и новые технологии в клинике внутренних болезней» НИЦ Первого Московского государственного медицинского университета им. И.М. Сеченова, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Chronomedicine and New Technologies in Internal Medicine, Research Centre, I.M. Sechenov First Moscow State Medical University, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2012</year></pub-date><volume>0</volume><issue>3</issue><fpage>85</fpage><lpage>87</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Беленков Ю.Н., Привалова Е.В., Данилогорская Ю.А., Железных Е.А., Щендрыгина А.А., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Беленков Ю.Н., Привалова Е.В., Данилогорская Ю.А., Железных Е.А., Щендрыгина А.А.</copyright-holder><copyright-holder xml:lang="en">Belenkov Y.N., Privalova E.V., Danilogorskaya Y.A., Zheleznykh E.A., Shchendrygina A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://russjcardiol.elpub.ru/jour/article/view/1233">https://russjcardiol.elpub.ru/jour/article/view/1233</self-uri><abstract><p>Факторы риска лежат в основе сердечно-сосудистого континуума. Артериальная гипертония является одним из наиболее значимых факторов риска и вносит существенный вклад в развитие сердечно – сосудистой заболеваемости и смертности от сердечнососудистых осложнений (ССО). Развитие последних обусловлено, в том числе, поражением сосудистого звена сердечно-сосудистой системы (ССС). В настоящее время цели антигипертензивной терапий заключаются не только в контроле цифр артериального давления, но также и в профилактике развития ССО. Препаратами выбора являются те лекарственные средства, которые, помимо антигипертензивных эффектов, обладают также проективным действием на сосудистую стенку.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>Risk factors are the cornerstone of the cardiovascular continuum concept. Arterial hypertension is one of major risk factors, which accounts for a substantial proportion of cardiovascular morbidity and mortality due to cardiovascular complications (CVC). The latter develop due to, among other reasons, the damage of the vascular component of cardiovascular system (CVS). Presently, the aims of antihypertensive treatment include not only control of blood pressure levels, but also CVC prevention. Antihypertensive medications of choice include the agents which also possess vasoprotective qualities.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>периндоприл</kwd><kwd>артериальная гипертензия</kwd><kwd>ремоделирование</kwd><kwd>микроциркуляция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ACE inhibitors</kwd><kwd>perindopril</kwd><kwd>arterial hypertension</kwd><kwd>remodeling</kwd><kwd>microcirculation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Shalnova S.A., Balanova J.A., Konstantinov B. D. et al. Hypertension: prevalence, awareness, reception of anti-hypertensive preparations and efficiency of treatment among the population of the Russian Federation RCJ 20064: 45–50. Russian (Шальнова С.А., Баланова Ю.А., Константинов В.В. и др. Артериальная гипертония: распространенность, осведомленность, прием антигипертензивных препаратов и эффективность лечения среди населения Российской Федерации. Российский кардиологический журнал 2006; 4: 45–50).</mixed-citation><mixed-citation xml:lang="en">Shalnova S.A., Balanova J.A., Konstantinov B. D. et al. Hypertension: prevalence, awareness, reception of anti-hypertensive preparations and efficiency of treatment among the population of the Russian Federation RCJ 20064: 45–50. Russian (Шальнова С.А., Баланова Ю.А., Константинов В.В. и др. Артериальная гипертония: распространенность, осведомленность, прием антигипертензивных препаратов и эффективность лечения среди населения Российской Федерации. Российский кардиологический журнал 2006; 4: 45–50).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Antonios T.F.T. et al. Rarefaction of Skin Capillaries in Borderline Essential Hypertension Suggests an Early Structural Abnormality. Hypertension 1999; 34:655–658</mixed-citation><mixed-citation xml:lang="en">Antonios T.F.T. et al. Rarefaction of Skin Capillaries in Borderline Essential Hypertension Suggests an Early Structural Abnormality. Hypertension 1999; 34:655–658</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ezzati M., Lopez A. D., et al. Comparative Risk Assessment Collaborating Group. Selected major risk factors and global and regional burden of disease. Lancet. 2002;360 (9343):1347–60.</mixed-citation><mixed-citation xml:lang="en">Ezzati M., Lopez A. D., et al. Comparative Risk Assessment Collaborating Group. Selected major risk factors and global and regional burden of disease. Lancet. 2002;360 (9343):1347–60.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Hypertension: management of hypertension in adults in primary care. NICE clinical guideline 34. www.nice.org.uk/CG034NICEguideline.</mixed-citation><mixed-citation xml:lang="en">Hypertension: management of hypertension in adults in primary care. NICE clinical guideline 34. www.nice.org.uk/CG034NICEguideline.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ceconi C, Fox K, Remme WJ et al. ACE inhibition with perindopril and endothelial dysfunction. Results of a substudy of the EUROPA study: PERTINENT. Cardiovasc Res 2007; 73: 237–46.</mixed-citation><mixed-citation xml:lang="en">Ceconi C, Fox K, Remme WJ et al. ACE inhibition with perindopril and endothelial dysfunction. Results of a substudy of the EUROPA study: PERTINENT. Cardiovasc Res 2007; 73: 237–46.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
